Patents by Inventor Joseph J. Lynch, Jr.

Joseph J. Lynch, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of treating heart failure with endothelin antagonists
    Patent number: 6380195
    Abstract: A composition for preventing and/or treating heart failure and ventricular dysfunction in a warm blooded animal comprising a therapeutically effective amount of an endothelin antagonist of the formula: is disclosed
    Type: Grant
    Filed: February 22, 2000
    Date of Patent: April 30, 2002
    Assignee: Banyu Pharmaceutical Co., Ltd.
    Inventors: Joseph J. Lynch, Jr., You-Tang Shen
  • Methods of treating or preventing cardiac arrhythmia
    Patent number: 6214809
    Abstract: A method of treating or preventing supraventricular tachyarrhythmias is disclosed which comprises the use of a compound which selectively blocks the ultra-rapidly-activating delayed rectifier K+ current (IKur) of the human atrium.
    Type: Grant
    Filed: April 19, 1999
    Date of Patent: April 10, 2001
    Assignee: Merck & Co., Inc.
    Inventors: Bernard Fermini, Joseph J. Lynch, Jr., Joseph J. Salata, Richard J. Swanson
  • Methods of treating or preventing cardiac arrhythmia
    Patent number: 6214810
    Abstract: This application discloses a method of treating or preventing atrial arrhythmias which utilizes compounds which are blockers of the ultra-rapidly-activating delayed rectifier K+ current (IKur) of the human atrium in a use-dependent and/or rate dependent manner, and which provide the selective block preferentially at fast heart rates so that the effect is realized or maximized when required.
    Type: Grant
    Filed: April 19, 1999
    Date of Patent: April 10, 2001
    Assignee: Merck & Co., Inc.
    Inventors: Bernard Fermini, Joseph J. Lynch, Jr., Joseph J. Salata, Richard J. Swanson
  • Method of treating heart failure with endothelin antagonists
    Patent number: 6087360
    Abstract: A method for preventing and/or treating heart failure and ventricular dysfunction in a warm blooded animal comprising administering to the warm blooded animal a therapeutically effective amount of an endothelin antagonist of the formula: as defined herein.
    Type: Grant
    Filed: August 11, 1998
    Date of Patent: July 11, 2000
    Assignee: Banyu Pharmaceutical Co., Ltd.
    Inventors: Joseph J. Lynch, Jr., You-Tang Shen
  • Methods of treating or preventing cardiac arrhythmia
    Patent number: 5969017
    Abstract: This application discloses a method of treating or preventing atrial arrhythmias which utilizes compounds which are blockers of the ultra-rapidly-activating delayed rectifier K.sup.+ current (I.sub.Kur) of the human atrium in a use-dependent and/or rate dependent manner, and which provide the selective block preferentially at fast heart rates so that the effect is realized or maximized when required.
    Type: Grant
    Filed: October 28, 1997
    Date of Patent: October 19, 1999
    Assignee: Merck & Co., Inc.
    Inventors: Joseph J. Lynch, Jr., Richard J. Swanson, Joseph J. Salata, Bernard Fermini
  • Methods of treating or preventing cardiac arrhythmia
    Patent number: 5935945
    Abstract: A method of treating or preventing supraventricular tachyarrhythmias is disclosed which comprises the use of a compound which selectively blocks the ultra-rapidly-activating delayed rectifier K.sup.+ current (I.sub.Kur) of the human atrium.
    Type: Grant
    Filed: October 28, 1997
    Date of Patent: August 10, 1999
    Assignee: Merck & Co., Inc.
    Inventors: Joseph J. Lynch, Jr., Richard J. Swanson, Joseph J. Salata, Bernard Fermini
  • Method of treating heart failure with endothelin antagonists
    Patent number: 5834483
    Abstract: A method for preventing and/or treating heart failure and ventricular dysfunction in a warm blooded animal comprising administering to the warm blooded animal a therapeutically effective amount of endothelin antagonists described herein.
    Type: Grant
    Filed: March 26, 1997
    Date of Patent: November 10, 1998
    Assignee: Merck & Co., Inc.
    Inventors: Joseph J. Lynch, Jr., You-Tang Shen
  • Pharmaceutical preparation
    Patent number: 5776930
    Abstract: A method of preventing, treating, terminating and protecting against cardiac arrhythmias, such as atrial, supraventricular and ventricular ectopy, tachycardia, flutter or fibrillation, including atrial, supraventricular and ventricular arrhythmias resulting from myocardial ischemic injury in a patient in need thereof, comprising administration of a selective I.sub.Ks antagonist and a beta-adrenergic receptor blocking agent, administered in combined therapy either simultaneously, separately or sequentially is presented. Additionally, a pharmaceutical preparation comprising a selective I.sub.Ks antagonist and a beta-adrenergic receptor blocking agent, wherein these compounds are administered simultaneously, separately or sequentially is presented.
    Type: Grant
    Filed: June 24, 1997
    Date of Patent: July 7, 1998
    Assignee: Merck & Company, Inc.
    Inventors: Joseph J. Lynch, Jr., Joseph J. Salata
  • Methods of treating cardiac arrhythmia
    Patent number: 5597818
    Abstract: Benzodiazepine analogs have been found to be useful in treating cardiac abnormalities.
    Type: Grant
    Filed: March 20, 1995
    Date of Patent: January 28, 1997
    Assignee: Merck & Co., Inc.
    Inventors: Michael C. Sanguinetti, Joseph J. Salata, Joseph J. Lynch, Jr.
  • Methods of treating cardiac arrhythmia
    Patent number: 5428031
    Abstract: Benzodiazepine analogs have been found to be useful in treating cardiac abnormalities.
    Type: Grant
    Filed: November 22, 1993
    Date of Patent: June 27, 1995
    Assignee: Merck & Co., Inc.
    Inventors: Michael C. Sanguinetti, Joseph J. Lynch, Jr., Joseph J. Salata