Patents by Inventor Joseph J. Noble

Joseph J. Noble has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CAR T CELL THERAPIES WITH ENHANCED EFFICACY
    Publication number: 20240076372
    Abstract: The invention provides methods for manufacturing optimized CAR T cell therapies and uses thereof. Specifically, the invention provides parameters that can be measured, e.g., evaluated, to manufacture CAR T cell therapies with optimized properties. The invention further provides methods of use in connection with said optimized CAR T cells.
    Type: Application
    Filed: March 6, 2023
    Publication date: March 7, 2024
    Inventors: Christopher Loren Nobles, Frederic Dixon Bushman, Joseph A. Fraietta, Simon Lacey, Jan J. Melenhorst, Carl H. June
  • Insert molding apparatus and method
    Publication number: 20040078998
    Abstract: An apparatus for making a molded article containing an insert includes an upper mold half and a lower mold half for mating with the upper mold half to provide a mold cavity therein. Either mold half can include a recess, an elevator opening in a lower portion of the recess, and an inwardly directed lip at an upper portion of the elevator opening. An elevator mechanism is provided which includes a lifter for supporting an insert to be secured to the article during a molding operation, and a lifting arrangement for raising and lowering the lifter through the elevator opening such that a peripheral edge of the insert supported on the lifter is clamped between the lifter and the lip when the lifting arrangement raises the lifter.
    Type: Application
    Filed: October 15, 2003
    Publication date: April 29, 2004
    Inventors: John W. Davis, Randall K. Fisher, Joseph J. Noble
  • Insert molding apparatus
    Patent number: 6699028
    Abstract: An apparatus for making a molded article containing an insert includes an upper mold half and a lower mold half for mating with the upper mold half to provide a mold cavity therein. Either mold half can include a recess, an elevator opening in a lower portion of the recess, and an inwardly directed lip at an upper portion of the elevator opening. An elevator mechanism is provided which includes a lifter for supporting an insert to be secured to the article during a molding operation, and a lifting arrangement for raising and lowering the lifter through the elevator opening such that a peripheral edge of the insert supported on the lifter is clamped between the lifter and the lip when the lifting arrangement raises the lifter.
    Type: Grant
    Filed: October 16, 2001
    Date of Patent: March 2, 2004
    Assignee: Schering-Plough HealthCare Products, Inc.
    Inventors: John W. Davis, Randall K. Fisher, Joseph J. Noble, Jr.
  • Insert molding apparatus and method
    Publication number: 20030070321
    Abstract: An apparatus for making a molded article containing an insert includes an upper mold half and a lower mold half for mating with the upper mold half to provide a mold cavity therein. Either mold half can include a recess, an elevator opening in a lower portion of the recess, and an inwardly directed lip at an upper portion of the elevator opening. An elevator mechanism is provided which includes a lifter for supporting an insert to be secured to the article during a molding operation, and a lifting arrangement for raising and lowering the lifter through the elevator opening such that a peripheral edge of the insert supported on the lifter is clamped between the lifter and the lip when the lifting arrangement raises the lifter.
    Type: Application
    Filed: October 16, 2001
    Publication date: April 17, 2003
    Inventors: John W. Davis, Randall K. Fisher, Joseph J. Noble