Abstract: The disclosure relates to double stranded ribonucleic acid (dsRNAi) agents and compositions targeting a SNCA gene, particularly in a CNS tissue, as well as methods of inhibiting expression of a SNCA gene and methods of treating subjects having a SNCA-associated neurodegenerative disease or disorder, e.g., Parkinson's Disease (PD), multiple system atrophy (MSA), Lewy body dementia (LBD), among other synucleinopathies, using such dsRNAi agents and compositions.

Abstract: A method and system for determining a path between nodes in a network are disclosed. In accordance with an embodiment of the present disclosure, a system for determining a path between nodes in a network comprises a destination node and a link aggregation group (LAG) that includes a first link and a second link. The system further comprises a source node communicatively coupled to the destination node by the LAG where the source node, the LAG and the destination node form a path. The source node is operable to determine a link availability status for each of the first and second links using a layer-2 protection scheme. The source node is further operable to monitor the path for connectivity based on the link availability status using a layer-3 protection scheme.

Abstract: According to a particular embodiment, a method for automatically assigning dynamic IP addresses without user interaction includes maintaining at least one pool of unused IP addresses. An advertisement message is transmitted from a first network element to at least one additional network element in a transport ring. The advertisement message identifies the first network element as providing IP address assignment services. The IP address request message from a second network element in the transport ring is received at the first network element. In response to the IP address request message, an IP address is dynamically assigned from the at least one pool of unused IP addresses. The dynamically assigned IP address is transmitted from the first network element to the second network element.

Abstract: A method and system for determining a path between nodes in a network are disclosed. In accordance with an embodiment of the present disclosure, a system for determining a path between nodes in a network comprises a destination node and a link aggregation group (LAG) that includes a first link and a second link. The system further comprises a source node communicatively coupled to the destination node by the LAG where the source node, the LAG and the destination node form a path. The source node is operable to determine a link availability status for each of the first and second links using a layer-2 protection scheme. The source node is further operable to monitor the path for connectivity based on the link availability status using a layer-3 protection scheme.

Abstract: According to a particular embodiment, a method for automatically assigning dynamic IP addresses without user interaction includes maintaining at least one pool of unused IP addresses. An advertisement message is transmitted from a first network element to at least one additional network element in a transport ring. The advertisement message identifies the first network element as providing IP address assignment services. The IP address request message from a second network element in the transport ring is received at the first network element. In response to the IP address request message, an IP address is dynamically assigned from the at least one pool of unused IP addresses. The dynamically assigned IP address is transmitted from the first network element to the second network element.