Abstract: Presystemic metabolism in intestine of bioactives such as phenylephrine is avoided by administering a subject (human or animal) the bioactive (e.g., phenylephrine) in combination with one or more inhibitors of sulfation (e.g., sulfotransferase enzymes aka SULTs). This can also be enhanced be co-administering inhibitors of monoamine oxidases aka, MAOs, and uridine diphosphate glucoronysl transferases, aka UGTs. Preferably the inhibitors are GRAS compounds. The one or more inhibitor compounds inhibit the enzymes responsible for rapid presystemic metabolism, thus allowing the bioactives (e.g., phenylephrine) to be more readily absorbed intact into the circulatory system.

Abstract: Presystemic metabolism in intestine of bioactives such as phenylephrine is avoided by administering a subject (human or animal) the bioactive (e.g., phenylephrine) in combination with one or more inhibitors of sulfation (e.g., sulfotransferase enzymes aka SULTs). This can also be enhanced be co-administering inhibitors of monoamine oxidases aka, MAOs, and uridine diphosphate glucoronysl transferases, aka UGTs. Preferably the inhibitors are GRAS compounds. The one or more inhibitor compounds inhibit the enzymes responsible for rapid presystemic metabolism, thus allowing the bioactives (e.g., phenylephrine) to be more readily absorbed intact into the circulatory system.

Abstract: A leaf collection system for lawn blower/vacuums is disclosed. The collection system includes a port coupling fitted to the exhaust port of a blower/vacuum, a dust cover, and a unique disposable collection bag. The disposable collection bag is constructed of an environmentally friendly, bio-degradeable plastic that will quickly decompose along with the organic leaves and lawn debris collected therein. Both sides of the collection bag has several rows of T-shaped slits and two rows of straight or I-shaped slits that allow air to escape from the bag but retain the leaves and lawn debris deposited therein. The collection bag is shaped to fit inside the dust cover that is fixed to the port coupling. The port coupling includes an elastic lock ring that secures the collection bag to the coupling. The dust cover envelops of the collection bag and shields the operator from the dust that passes through the collection bag.

Abstract: A leaf collection system for lawn blower/vacuums is disclosed. The collection system includes a port coupling fitted to the exhaust port of a blower/vacuum, a dust cover, and a unique disposable collection bag. The disposable collection bag is constructed of an environmentally friendly, bio-degradeable plastic that will quickly decompose along with the organic leaves and lawn debris collected therein. Both sides of the collection bag has several rows of T-shaped slits and two rows of straight or I-shaped slits that allow air to escape from the bag but retain the leaves and lawn debris deposited therein. The collection bag is shaped to fit inside the dust cover that is fixed to the port coupling. The port coupling includes an elastic lock ring that secures the collection bag to the coupling. The dust cover envelops of the collection bag and shields the operator from the dust that passes through the collection bag.