Abstract: A system for fractionating multiple fractions of particles from a sample includes a fractionation unit including a flow channel divided into two or more compartments by one or more porous membranes of known pore size and a flow module system in fluid connection with the fractionation unit. The flow module system further includes a sample container for the sample, a backwash container for a backwash fluid, and two or more collection containers for collection of fractionated portions of the sample, each of the collection containers being in fluid connection with a different one of the compartments. The system further includes a control system in operative connection with the flow module system to control flow.

Abstract: In certain aspects, the disclosure relates to an immune cell that has been engineered to comprise one or more heterologous polynucleotides that promote thanotransmission by the immune cell. The immune cell may also comprise one or more nucleic acid sequences that encode a chimeric antigen receptor (CAR). Methods of promoting thanotransmission, promoting immune response, and treating cancer using the engineered immune cells are also disclosed.

Abstract: In some examples, a system receives a representation of a lattice cell and information representing a target modified behavior of the lattice cell. The representation of the lattice cell including an arrangement of beams of the lattice cell. The system generates a modified lattice cell based on the representation of the lattice cell and the information, where the modified lattice cell includes the arrangement of the beams and an added behavior adjustment structure that is connected to a selected beam of the arrangement of the beams.

Abstract: An aroma dispensing system is provided. The aroma dispensing system includes an aroma blending device adapted to deliver at least one aroma substance to the nasal cavities of a consumer; a user interface configured for inputting and displaying information regarding the at least one aroma substance, and a memory component that stores a computer algorithm, the computer algorithm causing the system to analyze the input information in real-time in order to classify aroma preferences of the consumer, including recommending one or more in-store consumer products suitable to the consumer's aroma preferences.

Abstract: In certain aspects, the disclosure relates to a virus engineered to comprise one or more polynucleotides that promote thanotransmission by a target cell. Thanotransmission is communication between cells that is a result of activation of a cell turnover pathway in a target cell, which signals a responding cell to undergo a biological response. Methods of promoting thanotransmission by a target cell, methods of promoting an immune response in a subject, and methods of treating cancer in a subject are also disclosed.

Abstract: An aroma dispensing system is provided. The aroma dispensing system includes an aroma blending device adapted to deliver at least one aroma substance to the nasal cavities of a consumer; a user interface configured for inputting and displaying information regarding the at least one aroma substance, and a memory component that stores a computer algorithm, the computer algorithm causing the system to analyze the input information in real-time in order to classify aroma preferences of the consumer, including recommending one or more in-store consumer products suitable to the consumer's aroma preferences.

Abstract: A system comprising a respirator, a biochip, and an atomizer for studying respiratory pathogens. The respirator of the system is configured to create breathe-mimicking air movement, the biochip comprises an airway lumen in fluid communication with the respirator, and the atomizer is in fluid communication with the airway lumen of the biochip, according to various embodiments. The atomizer may be configured to generate droplets of a respiratory pathogen (e.g., from liquid inoculum). In various embodiments, the breath-mimicking air movement comprises air volume as a function of time, wherein the respirator is configured to generate breathing cycles.

Abstract: In certain aspects, the disclosure relates to a nucleic acid molecule encoding two or more different thanotransmission polypeptides. Thanotransmission is communication between cells that is a result of activation of a cell turnover pathway in a target cell, which signals a responding cell to undergo a biological response. Vectors (e.g., engineered viruses, plasmids and transposons), cells and pharmaceutical compositions comprising one or more nucleic acid molecules encoding two or more thanotransmision polypeptides are also disclosed. Methods of promoting thanotransmission by a target cell, methods of promoting an immune response in a subject, and methods of treating cancer in a subject are further disclosed.

Abstract: An aroma dispensing system is provided. The aroma dispensing system includes an aroma blending device adapted to deliver at least one aroma substance to the nasal cavities of a consumer; a user interface configured for inputting and displaying information regarding the at least one aroma substance, and a memory component that stores a computer algorithm, the computer algorithm causing the system to analyze the input information in real-time in order to classify aroma preferences of the consumer, including recommending one or more in-store consumer products suitable to the consumer's aroma preferences.

Abstract: A computing system configured to gather social media content includes a memory; a content collection and ingestion system, stored in the memory and configured, when executed on a computer processor, to communicate with one or more computing systems to direct a search of a content source using a received collection to request and to ingest the results of the directed search into a data store; and a content management system, stored in the memory and configured, when executed on a computer processor, to display the ingested results on a display.

Abstract: A system comprising a respirator, a biochip, and an atomizer for studying respiratory pathogens. The respirator of the system is configured to create breathe-mimicking air movement, the biochip comprises an airway lumen in fluid communication with the respirator, and the atomizer is in fluid communication with the airway lumen of the biochip, according to various embodiments. The atomizer may be configured to generate droplets of a respiratory pathogen (e.g., from liquid inoculum). In various embodiments, the breath-mimicking air movement comprises air volume as a function of time, wherein the respirator is configured to generate breathing cycles.

Abstract: A computing system configured to gather social media content includes a memory; a content collection and ingestion system, stored in the memory and configured, when executed on a computer processor, to communicate with one or more computing systems to direct a search of a content source using a received collection request and to ingest the results of the directed search into a data store; and a content management system, stored in the memory and configured, when executed on a computer processor, to display the ingested results on a display.

Abstract: A computing system configured to gather social media content includes a memory; a content collection and ingestion system, stored in the memory and configured, when executed on a computer processor, to communicate with one or more computing systems to direct a search of a content source using a received collection to request and to ingest the results of the directed search into a data store; and a content management system, stored in the memory and configured, when executed on a computer processor, to display the ingested results on a display.

Abstract: A computing system configured to gather social media content includes a memory; a content collection and ingestion system, stored in the memory and configured, when executed on a computer processor, to communicate with one or more computing systems to direct a search of a content source using a received collection request and to ingest the results of the directed search into a data store; and a content management system, stored in the memory and configured, when executed on a computer processor, to display the ingested results on a display.

Abstract: A computing system configured so gather social media content includes a memory; a content collection and ingestion system, stored in the memory and configured, when executed on a computer processor, to communicate with, one or more computing systems to direct a search of a content source using a received collection request and to ingest the insults of the directed search into a data store; and a content management system, stored in the memory and configured, when executed on a computer processor, to display the ingested results on a display,

Abstract: A computing system configured to gather social media content includes a memory; a content collection and ingestion system, stored in the memory and configured, when executed on a computer processor, to communicate with one or more computing systems to direct a search of a content source using a received collection request and to ingest the results of the directed search into a data store; and a content management system, stored in the memory and configured, when executed on a computer processor, to display the ingested results on a display.

Abstract: A computer holder has a protective case and a conformable backing which is attached to the case. The case holds the computer, and the backing can be formed as a soft membrane or as an accordion-like bellows. The backing is preferably made of a sewn fabric, leather and other similar soft materials, and may alternatively be made of injection molded silicone. The space within the backing can be selectively filled with small filling materials, a low viscosity fluid or a gas such as air. A two way valve, cap or handle can be attached to the backing to allow for a variation of the backing's fill level and shape. The holder can also have a strap attached to the case and a pocket formed in the backing.

Abstract: A computing system configured to gather social media content includes a memory; a content collection and ingestion system, stored in the memory and configured, when executed on a computer processor, to communicate with one or more computing systems to direct a search of a content source using a received collection request and to ingest the results of the directed search into a data store; and a content management system, stored in the memory and configured, when executed on a computer processor, to display the ingested results on a display.

Abstract: A method is provided for optimizing workplace engagement for a plurality of employees performing a plurality of tasks. The method may include receiving productivity data for each of the plurality of employees relative to each of the plurality of tasks and receiving forecasted demands for each of the plurality of tasks. The method may also include assigning one or more of the plurality of employees to one or more of the plurality of tasks. The employee task assignments may be based upon productivity data, availability data, and the forecasted demands. The method may further include determining that the forecasted demand for one of the plurality of tasks for the period of time falls below a predetermined threshold, and assigning an inexperienced employee to that one of the plurality of tasks.

Abstract: A method is provided for providing access to data relating to a plurality of processes associated with a supply chain network. The method may include identifying a user from a plurality of users. The method may also include identifying data from a plurality of data, wherein the identified data includes a subset of the plurality of data. The method may further include providing the user with access to the identified data. Providing the user with access to the identified data may include defining a user profile by establishing at least one permission associated with the identified data. The established permission may allow the user to access the identified data, and the user profile may be based on one of employee characteristics, work assignments, or geographical locations.