Abstract: The present invention provides compositions comprising a recombinant AAV and one or more pharmaceutically acceptable excipients. The compositions have improved stability and shelf life as compared to other AAV compositions.

Abstract: Disclosed herein are systems and methods that collapse risk in connection with electronic trades. The method includes collecting electronic trades, each electronic trade comprising party information, buy/sell information; determining hedge amounts for buys/sells for the electronic trades based on buy/sell data; simultaneously determining net hedge amounts for market participants; simultaneously determining a net hedge percentage for electronic trades; determining an individual hedge size for one or more first market participants based on a unique umbrella hedge value, wherein the umbrella hedge value for each of the first market participants is the net hedge percentage of said first market participant's net hedge amount; and distributing instructions to the plurality of market participants to fill the plurality of electronic trades at prices controlled by each first market participant's unique umbrella hedge value and by a composite mid-price for a plurality of second market participants.

Abstract: An internet based automated wagering system allows many participant to wager on outcomes of certain events associated with a game. The wagering can occur in real time or can be delayed. Presentations are made to participants indicating various events associated with the game and participants can then send to the system proposed wagers based on possible outcomes of the event as selected by each participant. The system then finds a partner for each participant and an engagement is established between the participants interested in the same wager and event outcome. The system can monitor events and determine their outcomes, or can obtain event outcome information from external sources.

Abstract: An internet based automated wagering system allows many participant to wager on outcomes of certain events associated with a game. The wagering can occur in real time or can be delayed. Presentations are made to participants indicating various events associated with the game and participants can then send to the system proposed wagers based on possible outcomes of the event as selected by each participant. The system then finds a partner for each participant and an engagement is established between the participants interested in the same wager and event outcome. The system can monitor events and determine their outcomes, or can obtain event outcome information from external sources.