Abstract: Systems and methods herein relate to an easy assemble centrifugal juicer. The centrifugal juicer includes a top section having a juice spout and pulp spout, wherein the top section defines a cavity with a first mating surface and a second mating surface; a strainer section having a strainer, a drive member, and a projection, the projection structured to engage with the first mating surface to couple the strainer section to the top section; and a motor housing structured to house a motor, wherein the motor is operatively coupled to a motor adapter structured to engage with the drive member.

Abstract: Anti-peptide antibodies (APAs) are extremely important tools for biomedical research. Many important techniques, such as immunoblots, ELISA immunoassays, immunocytochemistry, and protein microarrays are intrinsically linked to APA function and completely dependent on APA quality. Unfortunately, not all commercially-available APAs have good antigen binding characteristics; as a result, researchers are often unable to perform high quality protein analysis experiments. This disclosure describes a new method for the scalable production of polyclonal APAs using recombinant antigens. These recombinant peptide antigens have several advantages over traditional peptide antigens which improve the ease and speed of antibody production. The recombinant antigens can be scalably produced and purified much faster than traditional synthetic peptide-conjugates.

Abstract: Systems and methods herein relate to an easy assemble centrifugal juicer. The centrifugal juicer includes a top section having a juice spout and pulp spout, wherein the top section defines a cavity with a first mating surface and a second mating surface; a strainer section having a strainer, a drive member, and a projection, the projection structured to engage with the first mating surface to couple the strainer section to the top section; and a motor housing structured to house a motor, wherein the motor is operatively coupled to a motor adapter structured to engage with the drive member.

Abstract: Systems and methods herein relate to an easy assemble centrifugal juicer. The centrifugal juicer includes a top section having a juice spout and pulp spout, wherein the top section defines a cavity with a first mating surface and a second mating surface; a strainer section having a strainer, a drive member, and a projection, the projection structured to engage with the first mating surface to couple the strainer section to the top section; and a motor housing structured to house a motor, wherein the motor is operatively coupled to a motor adapter structured to engage with the drive member.

Abstract: A chopping system generally includes a container having a bottom wall and a sidewall together defining a cavity. The sidewall has a rim, and the bottom wall has an upper surface with a central area having an entirely smooth contour. The system also includes a drive assembly configured for mounting on the rim to cover the cavity, and the system further includes a working assembly comprising at least one working member configured for operative attachment to the drive assembly such that, when the drive assembly is mounted on the rim, the working member is disposed within the cavity. The system further includes a base attached to the working assembly such that the working member is rotatable relative to the base. The base has a bottom surface that substantially mirrors the contour of the upper surface within the central area so as to be seated substantially flush thereagainst.

Abstract: Anti-peptide antibodies (APAs) are extremely important tools for biomedical research. Many important techniques, such as immunoblots, ELISA immunoassays, immunocytochemistry, and protein microarrays are intrinsically linked to APA function and completely dependent on APA quality. Unfortunately, not all commercially-available APAs have good antigen binding characteristics; as a result, researchers are often unable to perform high quality protein analysis experiments. This disclosure describes a new method for the scalable production of polyclonal APAs using recombinant antigens. These recombinant peptide antigens have several advantages over traditional peptide antigens which improve the ease and speed of antibody production. The recombinant antigens can be scalably produced and purified much faster than traditional synthetic peptide-conjugates.

Abstract: Anti-peptide antibodies (APAs) are extremely important tools for biomedical research. Many important techniques, such as immunoblots, ELISA immunoassays, immunocytochemistry, and protein microarrays are intrinsically linked to APA function and completely dependent on APA quality. Unfortunately, not all commercially-available APAs have good antigen binding characteristics; as a result, researchers are often unable to perform high quality protein analysis experiments. This disclosure describes a new method for the scalable production of polyclonal APAs using recombinant antigens. These recombinant peptide antigens have several advantages over traditional peptide antigens which improve the ease and speed of antibody production. The recombinant antigens can be scalably produced and purified much faster than traditional synthetic peptide-conjugates.

Abstract: A pump includes a housing defining an interior volume, a diaphragm partitioning the interior volume into a pumping chamber and an actuating chamber, a diaphragm support associated with the actuating chamber and configured to limit movement of the diaphragm, and a dispersion element coupled to the housing. The dispersion element includes a network of channels that is configured to distribute a fluid within the pump.

Abstract: Systems and methods herein relate to an easy assemble centrifugal juicer. The centrifugal juicer includes a top section having a juice spout and pulp spout, wherein the top section defines a cavity with a first mating surface and a second mating surface; a strainer section having a strainer, a drive member, and a projection, the projection structured to engage with the first mating surface to couple the strainer section to the top section; and a motor housing structured to house a motor, wherein the motor is operatively coupled to a motor adapter structured to engage with the drive member.

Abstract: A pump includes a housing defining an interior volume, a diaphragm partitioning the interior volume into a pumping chamber and an actuating chamber, a diaphragm support associated with the actuating chamber and configured to limit movement of the diaphragm, and a dispersion element coupled to the housing. The dispersion element includes a network of channels that is configured to distribute a fluid within the pump.

Abstract: A pump includes a housing defining an interior volume, a diaphragm partitioning the interior volume into a pumping chamber and an actuating chamber, a diaphragm support associated with the actuating chamber and configured to limit movement of the diaphragm, and a dispersion element coupled to the housing. The dispersion element is configured to laterally distribute a fluid within the pump.

Abstract: Anti-peptide antibodies (APAs) are extremely important tools for biomedical research. Many important techniques, such as immunoblots, ELISA immunoassays, immunocytochemistry, and protein microarrays are intrinsically linked to APA function and completely dependent on APA quality. Unfortunately, not all commercially-available APAs have good antigen binding characteristics; as a result, researchers are often unable to perform high quality protein analysis experiments. This disclosure describes a new method for the scalable production of polyclonal APAs using recombinant antigens. These recombinant peptide antigens have several advantages over traditional peptide antigens which improve the ease and speed of antibody production. The recombinant antigens can be scalably produced and purified much faster than traditional synthetic peptide-conjugates.

Abstract: A pump includes a housing defining an interior volume, and a diaphragm, where the diaphragm partitions the interior volume into a pumping chamber and an actuating chamber. The diaphragm is formed from a polymeric material, and the pump further includes a diaphragm support configured to limit a stroke of the diaphragm. The diaphragm support includes an array of apertures through which fluid passes to interface with the diaphragm during operation of the pump.

Abstract: A pump includes a housing defining an interior volume, a diaphragm partitioning the interior volume into a pumping chamber and an actuating chamber, a diaphragm support associated with the actuating chamber and configured to limit movement of the diaphragm, and a dispersion element coupled to the housing. The dispersion element is configured to laterally distribute a fluid within the pump.

Abstract: A pricing optimization system can solve a constrained optimization problem by generating one or more prices for one or more items that satisfy a maximum number of prioritized constraints. The one or more generated prices can be one or more prices that represent a minimal deviation between the generated one or more prices and one or more original prices for the one or more items. By satisfying a maximum number of prioritized constraints, and by minimizing a deviation from the one or more original prices for the one or more items, the generated one or more prices are one or more optimal prices.

Abstract: A pricing optimization system can solve a constrained optimization problem by generating one or more prices for one or more items that satisfy a maximum number of prioritized constraints. The one or more generated prices can be one or more prices that represent a minimal deviation between the generated one or more prices and one or more original prices for the one or more items. By satisfying a maximum number of prioritized constraints, and by minimizing a deviation from the one or more original prices for the one or more items, the generated one or more prices are one or more optimal prices.

Abstract: A pump includes a housing defining an interior volume, and a diaphragm, where the diaphragm partitions the interior volume into a pumping chamber and an actuating chamber. The diaphragm is formed from a polymeric material, and the pump further includes a diaphragm support configured to limit a stroke of the diaphragm. The diaphragm support includes an array of apertures through which fluid passes to interface with the diaphragm during operation of the pump.

Abstract: The present invention concerns an isolated siRNA of from about 5 to about 20 nucleotides that mediates RNA interference. Also disclosed are methods of reducing expression of a target gene in a cell comprising obtaining at least one siRNA of 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, or 20 basepairs in length; and delivering the siRNA into the cell. The siRNAs can be chemically synthesized RNA or an analog of a naturally occurring RNA.

Abstract: The present invention concerns an isolated siRNA of from about 5 to about 20 nucleotides that mediates RNA interference. Also disclosed are methods of reducing expression of a target gene in a cell comprising obtaining at least one siRNA of 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, or 20 basepairs in length; and delivering the siRNA into the cell. The siRNAs can be chemically synthesized RNA or an analog of a naturally occurring RNA.

Abstract: The present invention concerns an isolated siRNA of from about 5 to about 20 nucleotides that mediates RNA interference. Also disclosed are methods of reducing expression of a target gene in a cell comprising obtaining at least one siRNA of 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, or 20 basepairs in length; and delivering the siRNA into the cell. The siRNAs can be chemically synthesized RNA or an analog of a naturally occurring RNA.