Patents by Inventor Joseph L. Bryant

Joseph L. Bryant has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9040100
    Abstract: A method of treating prostate cancer by administering a pharmaceutically-acceptable amount of a crude extract of the indigenous Jamaican plant Ball Moss (Tillandsia Recurvata) comprising one or more cycloartane isolates, and the isolates used in the method for eliciting thereby a kinase inhibitory response of prostate cancer cells by selectively inhibiting MRCK? kinase and angiogenesis of (growth of new blood vessels) to reduce the viability of prostate cancer cells. The method and compounds holds promise as a chemopreventive agent, without causing excessive damage to normal cells.
    Type: Grant
    Filed: May 6, 2014
    Date of Patent: May 26, 2015
    Inventors: Henry Lowe, Joseph L. Bryant
  • Publication number: 20150004260
    Abstract: A method of treating prostate cancer by administering a pharmaceutically-acceptable amount of a crude extract of the indigenous Jamaican plant Ball Moss (Tillandsia Recurvata) comprising one or more cycloartane isolates, and the isolates used in the method for eliciting thereby a kinase inhibitory response of prostate cancer cells by selectively inhibiting MRCK? kinase and angiogenesis of (growth of new blood vessels) to reduce the viability of prostate cancer cells. The method and compounds holds promise as a chemopreventive agent, without causing excessive damage to normal cells.
    Type: Application
    Filed: May 6, 2014
    Publication date: January 1, 2015
    Inventors: Henry Lowe, Joseph L. Bryant
  • Patent number: 8907117
    Abstract: Synthetic dicinnamate compounds and their analogs are disclosed that exhibit anti-tumor activity and/or an anti-inflammatory activity, and have beneficial activity principally in destroying cancer cells. Furthermore, methods for the extraction of the extracts are disclosed.
    Type: Grant
    Filed: September 10, 2012
    Date of Patent: December 9, 2014
    Inventors: Henry Lowe, Joseph L. Bryant
  • Patent number: 8715748
    Abstract: A method of treating prostate cancer by administering a pharmaceutically-acceptable amount of a crude extract of the indigenous Jamaican plant Ball Moss (Tillandsia Recurvata) comprising one or more cycloartane isolates, and the isolates used in the method for eliciting thereby a kinase inhibitory response of prostate cancer cells by selectively inhibiting MRCK? kinase and angiogenesis of (growth of new blood vessels) to reduce the viability of prostate cancer cells. The method and compounds holds promise as a chemopreventive agent, without causing excessive damage to normal cells.
    Type: Grant
    Filed: June 5, 2013
    Date of Patent: May 6, 2014
    Inventors: Henry Lowe, Joseph L. Bryant
  • Publication number: 20130210913
    Abstract: Synthetic dicinnamate compounds and their analogues are disclosed that exhibit anti-tumor activity and/or an anti-inflammatory activity, and have beneficial activity principally in destroying cancer cells. Furthermore, methods for the extraction of the extracts are disclosed.
    Type: Application
    Filed: September 10, 2012
    Publication date: August 15, 2013
    Inventors: Henry Lowe, Joseph L. Bryant
  • Publication number: 20040177393
    Abstract: The invention provides transgenic animals comprising a lentiviral transgene, such as an HIV transgene. Also within the scope of the invention are cells and eggs from the transgenic animal. Further included are methods for identifying therapeutic compounds for preventing lentiviral infection and treating associated disease (e.g. AIDS).
    Type: Application
    Filed: August 21, 2003
    Publication date: September 9, 2004
    Inventors: Joseph L. Bryant, William C. Reid, Harry G. Davis
  • Patent number: 6660904
    Abstract: The invention provides transgenic animals comprising a lentiviral transgene, such as an HIV transgene. Also within the scope of the invention are cells and eggs from the transgenic animal. Further included are methods for identifying therapeutic compounds for preventing lentiviral infection and treating associated disease (e.g. AIDS).
    Type: Grant
    Filed: October 10, 2000
    Date of Patent: December 9, 2003
    Assignee: University of Maryland Biotechnology Institute
    Inventors: Joseph L. Bryant, William C. Reid, Harry G. Davis, Jr.
  • Patent number: 6156952
    Abstract: The invention provides transgenic animals comprising a lentiviral transgene, such as an HIV transgene. Also within the scope of the invention are cells and eggs from the transgenic animal. Further included are methods for identifying therapeutic compounds for preventing lentiviral infection and treating associated disease (e.g. AIDS).
    Type: Grant
    Filed: April 9, 1998
    Date of Patent: December 5, 2000
    Assignee: Constituent Institution of the University of Maryland System
    Inventors: Joseph L. Bryant, William C. Reid, Harry G. Davis, Jr.
  • Patent number: 5877148
    Abstract: Methods useful for treating cancers are disclosed. The methods involve administering human chorionic gonadotropin (hCG) or human luteinizing hormone (hLH) to patients having cancers. Articles of manufacture that are useful for carrying out the described methods are also described. The claimed methods are effective against breast, prostate, ovary, and stomach carcinomas, as well as neuroblastomas, and Kaposi's sarcoma, among others.
    Type: Grant
    Filed: June 6, 1997
    Date of Patent: March 2, 1999
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Yanto Lunardi-Iskandar, Robert C. Gallo, Joseph L. Bryant
  • Patent number: 5770563
    Abstract: This invention identifies a biologically active group of peptide sequences from Type I repeat units of the extracellular matrix protein, human thrombospondin-1, identical or homologous to the sequence, KRFKQDGGWSHWSPWSSC (SEQ ID NO:30). The biological activities residing with the full sequences, portions thereof, and variants of the full or partial sequences are disclosed. The invention describes how biological activity may be enhanced by covalently linking these peptides to suitable carriers, preferably a branched, water-soluble polymer of low (or absent) toxicity and immunogenicity, such as polysucrose (Ficoll.TM.). The invention describes (1) a method for preparing such conjugates, (2) the use of the defined peptides or their conjugates in blocking or modifying the action on cellular processes of heparin (e.g.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: June 23, 1998
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: David D. Roberts, Philip J. Browning, Joseph L. Bryant, John K. Inman, Henry C. Krutzsch, Nenghua Guo
  • Patent number: 5677275
    Abstract: Methods useful for treating cancers are disclosed. The methods involve administering human chorionic gonadotropin (hCG) or human luteinizing hormone (hLH) to patients having cancers. Articles of manufacture that are useful for carrying out the described methods are also described. The claimed methods are effective against breast, prostate, ovary, and stomach carcinomas, as well as neuroblastomas, and Kaposi's sarcoma, among others.
    Type: Grant
    Filed: August 5, 1994
    Date of Patent: October 14, 1997
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Yanto Lunardi-Iskandar, Robert C. Gallo, Joseph L. Bryant