Patents by Inventor Joseph L. Calderon

Joseph L. Calderon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210290961
    Abstract: Systems for treating obstructive sleep apnea having an implanted stimulator with an internal sensor configured to generate sensory data corresponding to movement of the thoracic or abdominal cavity of a patient during respiration. The system includes a wireless communications link between the stimulator and at least one external sensor for sensing a patient's physiological parameter and is used to augment the sensory data from the internal sensor. The stimulator includes a stimulation system configured to deliver electrical stimulation to a nerve which innervates an upper airway muscle, such as the hypoglossal nerve to treat sleep apnea.
    Type: Application
    Filed: March 23, 2021
    Publication date: September 23, 2021
    Inventors: Robert J. Greenberg, HARSHIT R. SURI, JOSEPH L. CALDERON, BRIAN R. DEARDEN
  • Publication number: 20210187288
    Abstract: An electrode lead comprises a lead body, connector contacts affixed to the proximal end of the lead body, and a cuff body affixed to the distal end of the lead body. The cuff body is pre-shaped to transition from an unfurled state to a furled state, wherein the cuff body, when in the furled state has an inner surface for contacting a nerve and an overlapping inner cuff region and an outer cuff region. The electrode lead further comprise electrode contacts circumferentially disposed along the cuff body when in the furled state, such that at least one of the electrode contacts is located on the inner surface of the cuff body, and at least another of the electrode contacts is located between the overlapping inner and outer cuff regions. The electrode lead further comprises electrical conductors extending through the lead body respectively between the connector contacts and the electrode contacts.
    Type: Application
    Filed: March 3, 2021
    Publication date: June 24, 2021
    Applicant: THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH
    Inventors: Boon Khai Ng, Joseph L. Calderon
  • Patent number: 10967178
    Abstract: An electrode lead comprises a lead body, connector contacts affixed to the proximal end of the lead body, and a cuff body affixed to the distal end of the lead body. The cuff body is pre-shaped to transition from an unfurled state to a furled state, wherein the cuff body, when in the furled state has an inner surface for contacting a nerve and an overlapping inner cuff region and an outer cuff region. The electrode lead further comprise electrode contacts circumferentially disposed along the cuff body when in the furled state, such that at least one of the electrode contacts is located on the inner surface of the cuff body, and at least another of the electrode contacts is located between the overlapping inner and outer cuff regions. The electrode lead further comprises electrical conductors extending through the lead body respectively between the connector contacts and the electrode contacts.
    Type: Grant
    Filed: August 30, 2018
    Date of Patent: April 6, 2021
    Assignee: THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH
    Inventors: Boon Khai Ng, Joseph L. Calderon
  • Publication number: 20210038889
    Abstract: An electrode lead comprises an electrically insulative cuff body and at least three axially aligned electrode contacts circumferentially disposed along the inner surface of the cuff body when in the furled state. The electrode contacts may be circumferentially disposed around a nerve, and an electrical pulse train may be delivered to the electrode contacts thereby stimulating the nerve to treat obstructive sleep apnea. The electrical pulse train may be one that pre-conditions peripherally located nerve fascicles to not be stimulated, while stimulating centrally located nerve fascicles. A feedback mechanism can be used to titrate electrode contacts and electrical pulse train to the patient. A sensor that is affixed to the case of a neurostimulator can be used to measure physiological artifacts of respiration, and a motion detector can be used to sense tapping of the neurostimulator to toggle the neurostimulator between an ON position and an OFF position.
    Type: Application
    Filed: October 29, 2020
    Publication date: February 11, 2021
    Applicant: THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH
    Inventors: Harshit Suri, Joseph L. Calderon, Gregory Frederick Molnar, George S. Goding, JR., Alanie Atyabi, Siegmar Schmidt, William Dai, Brian Dearden, Desmond B. Keenan
  • Publication number: 20200368526
    Abstract: An electrode lead comprises an electrically insulative cuff body and at least three axially aligned electrode contacts circumferentially disposed along the inner surface of the cuff body when in the furled state. The electrode contacts may be circumferentially disposed around a nerve, and an electrical pulse train may be delivered to the electrode contacts thereby stimulating the nerve to treat obstructive sleep apnea. The electrical pulse train may be one that pre-conditions peripherally located nerve fascicles to not be stimulated, while stimulating centrally located nerve fascicles. A feedback mechanism can be used to titrate electrode contacts and electrical pulse train to the patient. A sensor that is affixed to the case of a neurostimulator can be used to measure physiological artifacts of respiration, and a motion detector can be used to sense tapping of the neurostimulator to toggle the neurostimulator between an ON position and an OFF position.
    Type: Application
    Filed: August 13, 2020
    Publication date: November 26, 2020
    Applicant: THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH
    Inventors: Harshit Suri, Joseph L. Calderon, Gregory Frederick Molnar, George S. Goding, JR., Alanie Atyabi, Siegmar Schmidt, William Dai, Brian Dearden, Desmond B. Keenan
  • Publication number: 20200206501
    Abstract: An electrode lead comprises an electrically insulative cuff body and at least three axially aligned electrode contacts circumferentially disposed along the inner surface of the cuff body when in the furled state. The electrode contacts may be circumferentially disposed around a nerve, and an electrical pulse train may be delivered to the electrode contacts thereby stimulating the nerve to treat obstructive sleep apnea. The electrical pulse train may be one that pre-conditions peripherally located nerve fascicles to not be stimulated, while stimulating centrally located nerve fascicles. A feedback mechanism can be used to titrate electrode contacts and electrical pulse train to the patient. A sensor that is affixed to the case of a neurostimulator can be used to measure physiological artifacts of respiration, and a motion detector can be used to sense tapping of the neurostimulator to toggle the neurostimulator between an ON position and an OFF position.
    Type: Application
    Filed: March 9, 2020
    Publication date: July 2, 2020
    Applicant: THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH
    Inventors: Harshit Suri, Joseph L Calderon, Gregory Frederick Molnar, George S. Goding, JR., Alanie Atyabi, Siegmar Schmidt, William Dai, Brian Dearden, Desmond B. Keenan
  • Publication number: 20190143110
    Abstract: An electrode lead comprises an electrically insulative cuff body and at least three axially aligned electrode contacts circumferentially disposed along the inner surface of the cuff body when in the furled state. The electrode contacts may be circumferentially disposed around a nerve, and an electrical pulse train may be delivered to the electrode contacts thereby stimulating the nerve to treat obstructive sleep apnea. The electrical pulse train may be one that pre-conditions peripherally located nerve fascicles to not be stimulated, while stimulating centrally located nerve fascicles. A feedback mechanism can be used to titrate electrode contacts and electrical pulse train to the patient. A sensor that is affixed to the case of a neurostimulator can be used to measure physiological artifacts of respiration, and a motion detector can be used to sense tapping of the neurostimulator to toggle the neurostimulator between an ON position and an OFF position.
    Type: Application
    Filed: January 11, 2019
    Publication date: May 16, 2019
    Applicant: THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH
    Inventors: Harshit Suri, Joseph L. Calderon, Gregory Frederick Molnar, George S. Goding, JR., Alanie Atyabi, Siegmar Schmidt, William Dai, Brian Dearden, Desmond B. Keenan
  • Publication number: 20190060646
    Abstract: An electrode lead comprises a lead body, connector contacts affixed to the proximal end of the lead body, and a cuff body affixed to the distal end of the lead body. The cuff body is pre-shaped to transition from an unfurled state to a furled state, wherein the cuff body, when in the furled state has an inner surface for contacting a nerve and an overlapping inner cuff region and an outer cuff region. The electrode lead further comprise electrode contacts circumferentially disposed along the cuff body when in the furled state, such that at least one of the electrode contacts is located on the inner surface of the cuff body, and at least another of the electrode contacts is located between the overlapping inner and outer cuff regions. The electrode lead further comprises electrical conductors extending through the lead body respectively between the connector contacts and the electrode contacts.
    Type: Application
    Filed: August 30, 2018
    Publication date: February 28, 2019
    Applicant: THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH
    Inventors: Boon Khai Ng, Joseph L. Calderon
  • Publication number: 20180221660
    Abstract: An electrode lead comprises an electrically insulative cuff body and at least three axially aligned electrode contacts circumferentially disposed along the inner surface of the cuff body when in the furled state. The electrode contacts may be circumferentially disposed around a nerve, and an electrical pulse train may be delivered to the electrode contacts thereby stimulating the nerve to treat obstructive sleep apnea. The electrical pulse train may be one that pre-conditions peripherally located nerve fascicles to not be stimulated, while stimulating centrally located nerve fascicles. A feedback mechanism can be used to titrate electrode contacts and electrical pulse train to the patient. A sensor that is affixed to the case of a neurostimulator can be used to measure physiological artifacts of respiration, and a motion detector can be used to sense tapping of the neurostimulator to toggle the neurostimulator between an ON position and an OFF position.
    Type: Application
    Filed: January 31, 2018
    Publication date: August 9, 2018
    Applicant: THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH
    Inventors: Harshit Suri, Joseph L. Calderon, Gregory Frederick Molnar, George S. Goding, Jr., Alanie Atyabi, Siegmar Schmidt, William Dai, Brian Dearden, Desmond B. Keenan
  • Patent number: 9724523
    Abstract: An interface for coupling with a percutaneously implantable lead is described. The interface includes a rotation based system to engage the terminal connector of the lead. The interface includes a brake which retains the lead in the lead port through friction, but allows the lead to exit the lead port if sufficient force is applied. The interface can be coupled with the lead without removing a stylet or stiffening wire from the lead.
    Type: Grant
    Filed: November 12, 2015
    Date of Patent: August 8, 2017
    Assignee: ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH
    Inventors: Joseph L. Calderon, Edward Hillery, Joseph Lockhart
  • Patent number: 9623220
    Abstract: Suture tracking dilators and methods for removing implanted medical devices such as microstimulators or microsensors from living tissue are described. A suture tracking dilator has a slit running along its axial length. The slit can have a curved portion. A suture is attached to a medical device prior to its implantation. To remove the implanted medical device, the free end of the suture is exposed and inserted in the slit in the suture tracking dilator. The suture is held under tension at its free end, the dilator is inserted in the living tissue and the dilator follows the suture to the implanted medical device. The medical device is removed by pulling on the free end of the suture.
    Type: Grant
    Filed: March 12, 2014
    Date of Patent: April 18, 2017
    Assignee: The Alfred E. Mann Foundation For Scientific Research
    Inventors: Michael R. Perrin, Kenneth L. Ripley, Joseph L. Calderon
  • Patent number: 9623219
    Abstract: Surgical dilators with tips having curved tapers and with a minimal distance between the distal and proximal ends of the dilator tips provide for precision placement of miniature medical devices at a target area in a body with reduced insertion force. A contour of a longitudinal cross section of the dilator tip comprises a first convex portion extending from the distal end to a first interface; a concave portion extending from the first interface to a second interface; and a second convex portion extending from the second interface to a third interface at the proximal end. The first convex portion and the second convex portion are convex relative to an interior of the tip and the concave portion is concave relative to the interior of the tip.
    Type: Grant
    Filed: February 6, 2014
    Date of Patent: April 18, 2017
    Assignee: The Alfred E. Mann Foundation For Scientific Research
    Inventor: Joseph L. Calderon
  • Publication number: 20160136435
    Abstract: An interface for coupling with a percutaneously implantable lead is described. The interface includes a rotation based system to engage the terminal connector of the lead. The interface includes a brake which retains the lead in the lead port through friction, but allows the lead to exit the lead port if sufficient force is applied. The interface can be coupled with the lead without removing a stylet or stiffening wire from the lead.
    Type: Application
    Filed: November 12, 2015
    Publication date: May 19, 2016
    Inventors: Joseph L. Calderon, Edward Hillery, Joseph Lockhart
  • Patent number: 9101753
    Abstract: The invention is a hollow electrode implantation device for inserting a flexible electrode, such as a Memberg electrode, in living tissue. The inserter has a longitudinal slot that accepts the electrode into the hollow center of the electrode implantation device. The slot is offset at least once forming one or more offset slots, where retainer tabs define the slots and assure retention of the electrode in the implantation device during insertion of the electrode into living tissue.
    Type: Grant
    Filed: September 8, 2009
    Date of Patent: August 11, 2015
    Assignee: Alfred E. Mann Foundation For Scientific Research
    Inventors: Joseph L. Calderon, Ross Davis, Delta Mishler
  • Publication number: 20140277022
    Abstract: Suture tracking dilators and methods for removing implanted medical devices such as microstimulators or microsensors from living tissue are described. A suture tracking dilator has a slit running along its axial length. The slit can have a curved portion. A suture is attached to a medical device prior to its implantation. To remove the implanted medical device, the free end of the suture is exposed and inserted in the slit in the suture tracking dilator. The suture is held under tension at its free end, the dilator is inserted in the living tissue and the dilator follows the suture to the implanted medical device. The medical device is removed by pulling on the free end of the suture.
    Type: Application
    Filed: March 12, 2014
    Publication date: September 18, 2014
    Applicant: ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH
    Inventors: MICHAEL R. PERRIN, KENNETH L. RIPLEY, JOSEPH L. CALDERON
  • Publication number: 20140277073
    Abstract: Surgical dilators with tips having curved tapers and with a minimal distance between the distal and proximal ends of the dilator tips provide for precision placement of miniature medical devices at a target area in a body with reduced insertion force. A contour of a longitudinal cross section of the dilator tip comprises a first convex portion extending from the distal end to a first interface; a concave portion extending from the first interface to a second interface; and a second convex portion extending from the second interface to a third interface at the proximal end. The first convex portion and the second convex portion are convex relative to an interior of the tip and the concave portion is concave relative to the interior of the tip.
    Type: Application
    Filed: February 6, 2014
    Publication date: September 18, 2014
    Applicant: ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH
    Inventor: Joseph L. Calderon
  • Publication number: 20080097519
    Abstract: A medical instrument, particularly a surgical instrument with a displaceable push/pull activation tube arranged on the proximal end of a hand manipulator, that also contains an inner tube for retaining a fixed jaw, for activating remote tool parts on the distal end, in which a force-limiting device limits the transmission of force to the remote tool parts from the hand manipulator via an extendable coil spring. The medical instrument optionally features a fiber scope to enable optical viewing to locate the implanted device for removal as well as a saline flush capability. The instrument has jaws that are cylindrical in shape to facilitate grasping an implanted cylindrical device.
    Type: Application
    Filed: October 20, 2006
    Publication date: April 24, 2008
    Applicant: ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH
    Inventors: Joseph L. Calderon, Joseph H. Schulman, Edward Hillery
  • Patent number: 6629011
    Abstract: Disclosed are a method and apparatus for initializing an additive process computer-controlled three-dimensional modeling machine which builds models on a modeling platform. The method, without operator intervention, senses the top surface of a substrate or other object mounted on the platform at a variety of preselected x, y locations and records the z-axis positions of the platform corresponding to the sensing of the object. Using the recorded z-axis positions, a z-start position for the modeling platform is calculated. The platform can be automatically placed at the calculated z-start position. The recorded z-axis positions can further be used to define a plane fitted to the substrate top surface. Optionally, the model can be built in a coordinate system defined by the plane.
    Type: Grant
    Filed: July 17, 2000
    Date of Patent: September 30, 2003
    Assignee: Stratasys, Inc.
    Inventors: Joseph L. Calderon, David L. Pollard, J. Samuel Batchelder
  • Patent number: 6367791
    Abstract: A system for mounting a slab substrate in a three-dimensional modeling machine includes two parallel rails positioned on opposite sides of a modeling platform. A blade extends along each rail, each blade having an inward-facing knife edge. A slab substrate having a width which approximates the distance between the two rails and having slits in its sides is loaded in the machine by lining up the slits, respectively, with each blade and pushing the substrate towards the rear of the platform as the knife edges cut into the substrate. Preferably, the platform includes a rear stopper to stop rearward motion of the substrate. The platform preferably also includes a retaining means at its front edge that is actuated to lock the substrate into place on the platform during modeling. The substrate is removed from the platform by deactuating the retaining means, if any, grasping the substrate, and sliding the substrate towards the front of the platform.
    Type: Grant
    Filed: July 7, 2000
    Date of Patent: April 9, 2002
    Assignee: Stratasys, Inc.
    Inventors: Joseph L. Calderon, Andrew M. Hahn