Patents by Inventor Joseph L. Kissil

Joseph L. Kissil has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR THE TREATMENT AND PREVENTION OF CANCER
    Publication number: 20100008901
    Abstract: The present inventions features methods for treating or preventing cancer (e.g., cancer of the central nervous system) by administering a compound that inhibits PAK kinase activity and/or merlin phosphorylation to a mammal (e.g., a human). The invention also provides screening methods for identifying additional inhibitors of PAK kinase activity and/or merlin phosphorylation.
    Type: Application
    Filed: April 3, 2009
    Publication date: January 14, 2010
    Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: TYLER E. JACKS, JOSEPH L. KISSIL
  • Methods of screening for compounds that decrease phosphorylation of merlin and may be useful in cancer treatment
    Patent number: 7514207
    Abstract: The present inventions features methods for treating or preventing cancer (e.g., cancer of the central nervous system) by administering a compound that inhibits PAK kinase activity and/or merlin phosphorylation to a mammal (e.g., a human). The invention also provides screening methods for identifying additional inhibitors of PAK kinase activity and/or merlin phosphorylation.
    Type: Grant
    Filed: August 13, 2002
    Date of Patent: April 7, 2009
    Assignee: Massachusetts Institute of Technology
    Inventors: Tyler E. Jacks, Joseph L. Kissil