Patents by Inventor Joseph Leon
Joseph Leon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240316564Abstract: An analysis system assembly and method for analyzing a plurality of samples and handling the cryogenically cooled samples from a shipping dewar into a position for analysis by an x-ray based analysis system. The system and method include a basket component containing a plurality of sample magazines each containing a plurality of samples, all covered by a volume of cryogenic liquid. The basket is transported from the shipping dewar to a transfer dewar. Cover components of the magazines are removed while the basket and magazines are submerged in a cryogenic liquid of the transfer dewar. The basket is removed from the transfer dewar and placed into a staging dewar of the analysis system. A robotic manipulator of the analysis system can then locate and transport individual samples to a sample stage of the analysis system.Type: ApplicationFiled: March 22, 2023Publication date: September 26, 2024Applicant: RIGAKU AMERICAS CORPORATIONInventors: Michael HICKMAN, John Dzung Tien TRUONG, Thomas Leon HENDRIXSON, Kevin Douglas LA BLUE, Joseph David FERRARA
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Publication number: 20240100744Abstract: A system and method for recycling and repurposing used tires. The system includes a plurality of modules for automatically repurposing used tires into fabrication of structural members or devices including but not limited to tie-downs, attachment cables, speed bumps, tire chocks, pet scratching posts, fencing, safety barriers, and more. The treads of the tires are used for making elongated strips which are joined using adhesive(s) for forming structures. In some embodiments, the temperature and pressure for the repurposing process can be adjusted using an interface. The used tires are cleaned and waste material is removed after treads are separated.Type: ApplicationFiled: September 20, 2023Publication date: March 28, 2024Inventor: Joseph Leon
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Patent number: 11909422Abstract: A deep neural network (“DNN”) module compresses and decompresses neuron-generated activation data to reduce the utilization of memory bus bandwidth. The compression unit receives an uncompressed chunk of data generated by a neuron in the DNN module. The compression unit generates a mask portion and a data portion of a compressed output chunk. The mask portion encodes the presence and location of the zero and non-zero bytes in the uncompressed chunk of data. The data portion stores truncated non-zero bytes from the uncompressed chunk of data. A decompression unit receives a compressed chunk of data from memory in the DNN processor or memory of an application host. The decompression unit decompresses the compressed chunk of data using the mask portion and the data portion.Type: GrantFiled: November 11, 2022Date of Patent: February 20, 2024Assignee: Microsoft Technology Licensing, LLCInventors: Joseph Leon Corkery, Benjamin Eliot Lundell, Larry Marvin Wall, Chad Balling McBride, Amol Ashok Ambardekar, George Petre, Kent D. Cedola, Boris Bobrov
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Publication number: 20230071352Abstract: A deep neural network (“DNN”) module can compress and decompress neuron-generated activation data to reduce the utilization of memory bus bandwidth. The compression unit can receive an uncompressed chunk of data generated by a neuron in the DNN module. The compression unit generates a mask portion and a data portion of a compressed output chunk. The mask portion encodes the presence and location of the zero and non-zero bytes in the uncompressed chunk of data. The data portion stores truncated non-zero bytes from the uncompressed chunk of data. A decompression unit can receive a compressed chunk of data from memory in the DNN processor or memory of an application host. The decompression unit decompresses the compressed chunk of data using the mask portion and the data portion. This can reduce memory bus utilization, allow a DNN module to complete processing operations more quickly, and reduce power consumption.Type: ApplicationFiled: November 11, 2022Publication date: March 9, 2023Inventors: Joseph Leon CORKERY, Benjamin Eliot LUNDELL, Larry Marvin WALL, Chad Balling McBRIDE, Amol Ashok AMBARDEKAR, George PETRE, Kent D. CEDOLA, Boris BOBROV
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Publication number: 20230010079Abstract: A pressure transducer assembly is disclosed for directly monitoring pressure in a fluid which flows through the assembly. The pressure transducer can include a housing comprising a flow restrictor, an inlet port, and an outlet port. A poppet can be coupled with the housing. The flow restrictor can be defined by a valve seat of the housing between the inlet port and the outlet port.Type: ApplicationFiled: September 21, 2022Publication date: January 12, 2023Inventors: Christopher Arjun Khorana, Daniel M. Harps, Weiwei Hu, Jonathan Pierre Rey, Joseph Leon Lutgen
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Patent number: 11528033Abstract: A deep neural network (“DNN”) module compresses and decompresses neuron-generated activation data to reduce the utilization of memory bus bandwidth. The compression unit receives an uncompressed chunk of data generated by a neuron in the DNN module. The compression unit generates a mask portion and a data portion of a compressed output chunk. The mask portion encodes the presence and location of the zero and non-zero bytes in the uncompressed chunk of data. The data portion stores truncated non-zero bytes from the uncompressed chunk of data. A decompression unit receives a compressed chunk of data from memory in the DNN processor or memory of an application host. The decompression unit decompresses the compressed chunk of data using the mask portion and the data portion.Type: GrantFiled: April 13, 2018Date of Patent: December 13, 2022Assignee: MICROSOFT TECHNOLOGY LICENSING, LLCInventors: Joseph Leon Corkery, Benjamin Eliot Lundell, Larry Marvin Wall, Chad Balling McBride, Amol Ashok Ambardekar, George Petre, Kent D. Cedola, Boris Bobrov
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Patent number: 11253512Abstract: A opioid taper regimen, and its method of manufacture, for use in a method of opioid reduction leading to abstinence. Said regimen is administered within the range of 2 to 4 years, or more. The regimen comprises novel approaches to common problems encountered during tapers of low dose opioid addiction. The reduction regimen is generally linear; reduces the dosage level once per week; doses every six hours; reduces doses by steps in the range of about 0.001 to 0.0500 mg; has, near the end, ten weeks of doses of about 0.0025 mg buprenorphine q.i.d.; followed by four or more weeks of placebos. Instructions for manufacture of doses that differ by 0.0025 mg and 0.0050 mg buprenorphine are specified.Type: GrantFiled: April 7, 2020Date of Patent: February 22, 2022Inventor: Joseph Leon Grossman
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Patent number: 10906965Abstract: Disclosed herein is a method for identifying TREM-1's ligand and antibodies, or fragments thereof, which are capable of modifying the function of TREM-1's ligand. Antibodies that reduce or block TREM-1 activation may be identified and selected using this method. Antibodies that bind to TREM-1's ligand and reduce TREM-1 activity may be suitable for use as medicaments.Type: GrantFiled: October 25, 2018Date of Patent: February 2, 2021Assignee: NOVO NORDISK A/SInventors: Vibeke Westphal Stennicke, Christine Brender Read, Joseph Leon Kuijper, Xiaoting Tang, Mark Heipel, Siv Annegrethe Hjorth
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Publication number: 20200316058Abstract: A opioid taper regimen, and its method of manufacture, for use in a method of opioid reduction leading to abstinence. Said regimen is administered within the range of 2 to 4 years, or more. The regimen comprises novel approaches to common problems encountered during tapers of low dose opioid addiction. The reduction regimen is generally linear; reduces the dosage level once per week; doses every six hours; reduces doses by steps in the range of about 0.001 to 0.0500 mg; has, near the end, ten weeks of doses of about 0.0025 mg buprenorphine q.i.d.; followed by four or more weeks of placebos. Instructions for manufacture of doses that differ by 0.0025 mg and 0.0050 mg buprenorphine are specified.Type: ApplicationFiled: April 7, 2020Publication date: October 8, 2020Inventor: Joseph Leon Grossman
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Publication number: 20190119367Abstract: Disclosed herein is a method for identifying TREM-1's ligand and antibodies, or fragments thereof, which are capable of modifying the function of TREM-1's ligand. Antibodies that reduce or block TREM-1 activation may be identified and selected using this method. Antibodies that bind to TREM-1's ligand and reduce TREM-1 activity may be suitable for use as medicaments.Type: ApplicationFiled: October 25, 2018Publication date: April 25, 2019Applicant: Novo Nordisk A/SInventors: Vibeke Westphal STENNICKE, Christine Brender READ, Joseph Leon KUIJPER, Xiaoting TANG, Mark HEIPEL, Siv Annegrethe HJORTH
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Patent number: 10260620Abstract: One method for running in a worm gear of an electromechanical steering system may comprise preparing the electromechanical servo steering system in a preassembled state in which one end of a worm shaft close to a motor or an end remote from the motor is mounted rotatably in a bearing in the gear housing and the respective other end of the worm shaft is movable in a radial direction so as to form a free end; rotatably mounting the free end of the worm shaft in an adjustable pretensioning device that is configured to pretension the worm shaft in a direction of the worm wheel in the engagement; adjusting the pretensioning device by way of a control device for generating a defined pretensioning of the engagement; and driving the worm shaft as a function of the control device at a defined rotational speed for a determined period of time.Type: GrantFiled: December 11, 2014Date of Patent: April 16, 2019Assignees: THYSSENKRUPP PRESTA AG, THYSSENKRUPP AGInventors: Joseph-Léon Strobel, Paul Schwarzhans
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Patent number: 10150809Abstract: Disclosed herein is a method for identifying TREM-1's ligand and antibodies, or fragments thereof, which are capable of modifying the function of TREM-1's ligand. Antibodies that reduce or block TREM-1 activation may be identified and selected using this method. Antibodies that bind to TREM-1's ligand and reduce TREM-1 activity may be suitable for use as medicaments.Type: GrantFiled: April 10, 2017Date of Patent: December 11, 2018Assignee: Bristol-Myers Squibb CompanyInventors: Vibeke Westphal Stennicke, Christine Brender Read, Joseph Leon Kuijper, Xiaoting Tang, Mark Heipel, Siv Annegrethe Hjorth
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Publication number: 20180346584Abstract: Novel polypeptide combinations, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor17-containing multimeric or heterodimer cytokine receptors that may be used as novel cytokine antagonists, and within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. The present invention also includes methods for producing the multimeric or heterodimeric cytokine receptor, uses therefor and antibodies thereto.Type: ApplicationFiled: August 10, 2018Publication date: December 6, 2018Inventors: Cindy A. Sprecher, Joseph Leon Kuijper, Maria M. Dasovich, Francis J. Grant, Theodore E. Whitmore, Angela K. Hammond, Julia E. Novak, Jane A. Gross, Stacey R. Dillon
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Patent number: 10137926Abstract: A steering shaft for a motor vehicle steering system may be used in connection with a variety of power assistance mechanisms. The steering shaft may comprise a first shaft part and a second shaft part that are rotationally-elastically coupled by way of a torsion bar. In order to transmit torque, the torsion bar may be received in a bore of the first shaft part and coupled to both the first and second shaft parts. In many cases, a first end of the torsion bar is coupled to the first shaft part, and a second end of the torsion bar is coupled to the second shaft part. The torsion bar may be mounted in the bore such that it can be rotated with respect to the first shaft part via a bearing element. In some examples, the bearing element comprises a prestressing element.Type: GrantFiled: February 25, 2015Date of Patent: November 27, 2018Assignees: THYSSENKRUPP PRESTA AG, THYSSENKRUPP AGInventor: Joseph Léon Strobel
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Publication number: 20180300606Abstract: A deep neural network (“DNN”) module can compress and decompress neuron-generated activation data to reduce the utilization of memory bus bandwidth. The compression unit can receive an uncompressed chunk of data generated by a neuron in the DNN module. The compression unit generates a mask portion and a data portion of a compressed output chunk. The mask portion encodes the presence and location of the zero and non-zero bytes in the uncompressed chunk of data. The data portion stores truncated non-zero bytes from the uncompressed chunk of data. A decompression unit can receive a compressed chunk of data from memory in the DNN processor or memory of an application host. The decompression unit decompresses the compressed chunk of data using the mask portion and the data portion. This can reduce memory bus utilization, allow a DNN module to complete processing operations more quickly, and reduce power consumption.Type: ApplicationFiled: April 13, 2018Publication date: October 18, 2018Inventors: Joseph Leon CORKERY, Benjamin Eliot LUNDELL, Larry Marvin WALL, Chad Balling McBRIDE, Amol Ashok AMBARDEKAR, George PETRE, Kent D. CEDOLA, Boris BOBROV
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Publication number: 20180016326Abstract: Disclosed herein is a method for identifying TREM-1's ligand and antibodies, or fragments thereof, which are capable of modifying the function of TREM-1's ligand. Antibodies that reduce or block TREM-1 activation may be identified and selected using this method. Antibodies that bind to TREM-1's ligand and reduce TREM-1 activity may be suitable for use as medicaments.Type: ApplicationFiled: April 10, 2017Publication date: January 18, 2018Inventors: Vibeke Westphal STENNICKE, Christine Brender Read, Joseph Leon Kuijper, Xiaoting Tang, Mark Heipel, Siv Annegrethe Hjorth
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Publication number: 20170369580Abstract: Novel polypeptide combinations, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor17-containing multimeric or heterodimer cytokine receptors that may be used as novel cytokine antagonists, and within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. The present invention also includes methods for producing the multimeric or heterodimeric cytokine receptor, uses therefor and antibodies thereto.Type: ApplicationFiled: September 11, 2017Publication date: December 28, 2017Inventors: Cindy A. Sprecher, Joseph Leon Kuijper, Maria M. Dasovich, Francis J. Grant, Theodore E. Whitmore, Angela K. Hammond, Julia E. Novak, Jane A Gross, Stacey R. Dillon
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Patent number: 9663568Abstract: Disclosed herein is a method for identifying TREM-1's ligand and antibodies, or fragments thereof, which are capable of modifying the function of TREM-1's ligand. Antibodies that reduce or block TREM-1 activation may be identified and selected using this method. Antibodies that bind to TREM-1's ligand and reduce TREM-1 activity may be suitable for use as medicaments.Type: GrantFiled: November 30, 2012Date of Patent: May 30, 2017Assignee: Novo Nordisk A/SInventors: Vibeke Westphal Stennicke, Christine Brender Read, Joseph Leon Kuijper, Xiaoting Tang, Mark Heipel, Siv Annegrethe Hjorth
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Publication number: 20170072988Abstract: A steering shaft for a motor vehicle steering system may be used in connection with a variety of power assistance mechanisms. The steering shaft may comprise a first shaft part and a second shaft part that are rotationally-elastically coupled by way of a torsion bar. In order to transmit torque, the torsion bar may be received in a bore of the first shaft part and coupled to both the first and second shaft parts. In many cases, a first end of the torsion bar is coupled to the first shaft part, and a second end of the torsion bar is coupled to the second shaft part. The torsion bar may be mounted in the bore such that it can be rotated with respect to the first shaft part via a bearing element. In some examples, the bearing element comprises a prestressing element.Type: ApplicationFiled: February 25, 2015Publication date: March 16, 2017Applicants: ThyssenKrupp Presta AG, ThyssenKrupp AGInventor: Joseph Léon STROBEL
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Publication number: 20160341304Abstract: One method for running in a worm gear of an electromechanical steering system may comprise preparing the electromechanical servo steering system in a preassembled state in which one end of a worm shaft close to a motor or an end remote from the motor is mounted rotatably in a bearing in the gear housing and the respective other end of the worm shaft is movable in a radial direction so as to form a free end; rotatably mounting the free end of the worm shaft in an adjustable pretensioning device that is configured to pretension the worm shaft in a direction of the worm wheel in the engagement; adjusting the pretensioning device by way of a control device for generating a defined pretensioning of the engagement; and driving the worm shaft as a function of the control device at a defined rotational speed for a determined period of time.Type: ApplicationFiled: December 11, 2014Publication date: November 24, 2016Applicants: ThyssenKrupp Presta AG, ThyssenKrupp AGInventors: Joseph-Léon STROBEL, Paul SCHWARZHANS