Patents by Inventor Joseph Leon

Joseph Leon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240316564
    Abstract: An analysis system assembly and method for analyzing a plurality of samples and handling the cryogenically cooled samples from a shipping dewar into a position for analysis by an x-ray based analysis system. The system and method include a basket component containing a plurality of sample magazines each containing a plurality of samples, all covered by a volume of cryogenic liquid. The basket is transported from the shipping dewar to a transfer dewar. Cover components of the magazines are removed while the basket and magazines are submerged in a cryogenic liquid of the transfer dewar. The basket is removed from the transfer dewar and placed into a staging dewar of the analysis system. A robotic manipulator of the analysis system can then locate and transport individual samples to a sample stage of the analysis system.
    Type: Application
    Filed: March 22, 2023
    Publication date: September 26, 2024
    Applicant: RIGAKU AMERICAS CORPORATION
    Inventors: Michael HICKMAN, John Dzung Tien TRUONG, Thomas Leon HENDRIXSON, Kevin Douglas LA BLUE, Joseph David FERRARA
  • Publication number: 20240100744
    Abstract: A system and method for recycling and repurposing used tires. The system includes a plurality of modules for automatically repurposing used tires into fabrication of structural members or devices including but not limited to tie-downs, attachment cables, speed bumps, tire chocks, pet scratching posts, fencing, safety barriers, and more. The treads of the tires are used for making elongated strips which are joined using adhesive(s) for forming structures. In some embodiments, the temperature and pressure for the repurposing process can be adjusted using an interface. The used tires are cleaned and waste material is removed after treads are separated.
    Type: Application
    Filed: September 20, 2023
    Publication date: March 28, 2024
    Inventor: Joseph Leon
  • Patent number: 11909422
    Abstract: A deep neural network (“DNN”) module compresses and decompresses neuron-generated activation data to reduce the utilization of memory bus bandwidth. The compression unit receives an uncompressed chunk of data generated by a neuron in the DNN module. The compression unit generates a mask portion and a data portion of a compressed output chunk. The mask portion encodes the presence and location of the zero and non-zero bytes in the uncompressed chunk of data. The data portion stores truncated non-zero bytes from the uncompressed chunk of data. A decompression unit receives a compressed chunk of data from memory in the DNN processor or memory of an application host. The decompression unit decompresses the compressed chunk of data using the mask portion and the data portion.
    Type: Grant
    Filed: November 11, 2022
    Date of Patent: February 20, 2024
    Assignee: Microsoft Technology Licensing, LLC
    Inventors: Joseph Leon Corkery, Benjamin Eliot Lundell, Larry Marvin Wall, Chad Balling McBride, Amol Ashok Ambardekar, George Petre, Kent D. Cedola, Boris Bobrov
  • Publication number: 20230071352
    Abstract: A deep neural network (“DNN”) module can compress and decompress neuron-generated activation data to reduce the utilization of memory bus bandwidth. The compression unit can receive an uncompressed chunk of data generated by a neuron in the DNN module. The compression unit generates a mask portion and a data portion of a compressed output chunk. The mask portion encodes the presence and location of the zero and non-zero bytes in the uncompressed chunk of data. The data portion stores truncated non-zero bytes from the uncompressed chunk of data. A decompression unit can receive a compressed chunk of data from memory in the DNN processor or memory of an application host. The decompression unit decompresses the compressed chunk of data using the mask portion and the data portion. This can reduce memory bus utilization, allow a DNN module to complete processing operations more quickly, and reduce power consumption.
    Type: Application
    Filed: November 11, 2022
    Publication date: March 9, 2023
    Inventors: Joseph Leon CORKERY, Benjamin Eliot LUNDELL, Larry Marvin WALL, Chad Balling McBRIDE, Amol Ashok AMBARDEKAR, George PETRE, Kent D. CEDOLA, Boris BOBROV
  • Publication number: 20230010079
    Abstract: A pressure transducer assembly is disclosed for directly monitoring pressure in a fluid which flows through the assembly. The pressure transducer can include a housing comprising a flow restrictor, an inlet port, and an outlet port. A poppet can be coupled with the housing. The flow restrictor can be defined by a valve seat of the housing between the inlet port and the outlet port.
    Type: Application
    Filed: September 21, 2022
    Publication date: January 12, 2023
    Inventors: Christopher Arjun Khorana, Daniel M. Harps, Weiwei Hu, Jonathan Pierre Rey, Joseph Leon Lutgen
  • Patent number: 11528033
    Abstract: A deep neural network (“DNN”) module compresses and decompresses neuron-generated activation data to reduce the utilization of memory bus bandwidth. The compression unit receives an uncompressed chunk of data generated by a neuron in the DNN module. The compression unit generates a mask portion and a data portion of a compressed output chunk. The mask portion encodes the presence and location of the zero and non-zero bytes in the uncompressed chunk of data. The data portion stores truncated non-zero bytes from the uncompressed chunk of data. A decompression unit receives a compressed chunk of data from memory in the DNN processor or memory of an application host. The decompression unit decompresses the compressed chunk of data using the mask portion and the data portion.
    Type: Grant
    Filed: April 13, 2018
    Date of Patent: December 13, 2022
    Assignee: MICROSOFT TECHNOLOGY LICENSING, LLC
    Inventors: Joseph Leon Corkery, Benjamin Eliot Lundell, Larry Marvin Wall, Chad Balling McBride, Amol Ashok Ambardekar, George Petre, Kent D. Cedola, Boris Bobrov
  • Patent number: 11253512
    Abstract: A opioid taper regimen, and its method of manufacture, for use in a method of opioid reduction leading to abstinence. Said regimen is administered within the range of 2 to 4 years, or more. The regimen comprises novel approaches to common problems encountered during tapers of low dose opioid addiction. The reduction regimen is generally linear; reduces the dosage level once per week; doses every six hours; reduces doses by steps in the range of about 0.001 to 0.0500 mg; has, near the end, ten weeks of doses of about 0.0025 mg buprenorphine q.i.d.; followed by four or more weeks of placebos. Instructions for manufacture of doses that differ by 0.0025 mg and 0.0050 mg buprenorphine are specified.
    Type: Grant
    Filed: April 7, 2020
    Date of Patent: February 22, 2022
    Inventor: Joseph Leon Grossman
  • Patent number: 10906965
    Abstract: Disclosed herein is a method for identifying TREM-1's ligand and antibodies, or fragments thereof, which are capable of modifying the function of TREM-1's ligand. Antibodies that reduce or block TREM-1 activation may be identified and selected using this method. Antibodies that bind to TREM-1's ligand and reduce TREM-1 activity may be suitable for use as medicaments.
    Type: Grant
    Filed: October 25, 2018
    Date of Patent: February 2, 2021
    Assignee: NOVO NORDISK A/S
    Inventors: Vibeke Westphal Stennicke, Christine Brender Read, Joseph Leon Kuijper, Xiaoting Tang, Mark Heipel, Siv Annegrethe Hjorth
  • Publication number: 20200316058
    Abstract: A opioid taper regimen, and its method of manufacture, for use in a method of opioid reduction leading to abstinence. Said regimen is administered within the range of 2 to 4 years, or more. The regimen comprises novel approaches to common problems encountered during tapers of low dose opioid addiction. The reduction regimen is generally linear; reduces the dosage level once per week; doses every six hours; reduces doses by steps in the range of about 0.001 to 0.0500 mg; has, near the end, ten weeks of doses of about 0.0025 mg buprenorphine q.i.d.; followed by four or more weeks of placebos. Instructions for manufacture of doses that differ by 0.0025 mg and 0.0050 mg buprenorphine are specified.
    Type: Application
    Filed: April 7, 2020
    Publication date: October 8, 2020
    Inventor: Joseph Leon Grossman
  • Publication number: 20190119367
    Abstract: Disclosed herein is a method for identifying TREM-1's ligand and antibodies, or fragments thereof, which are capable of modifying the function of TREM-1's ligand. Antibodies that reduce or block TREM-1 activation may be identified and selected using this method. Antibodies that bind to TREM-1's ligand and reduce TREM-1 activity may be suitable for use as medicaments.
    Type: Application
    Filed: October 25, 2018
    Publication date: April 25, 2019
    Applicant: Novo Nordisk A/S
    Inventors: Vibeke Westphal STENNICKE, Christine Brender READ, Joseph Leon KUIJPER, Xiaoting TANG, Mark HEIPEL, Siv Annegrethe HJORTH
  • Patent number: 10260620
    Abstract: One method for running in a worm gear of an electromechanical steering system may comprise preparing the electromechanical servo steering system in a preassembled state in which one end of a worm shaft close to a motor or an end remote from the motor is mounted rotatably in a bearing in the gear housing and the respective other end of the worm shaft is movable in a radial direction so as to form a free end; rotatably mounting the free end of the worm shaft in an adjustable pretensioning device that is configured to pretension the worm shaft in a direction of the worm wheel in the engagement; adjusting the pretensioning device by way of a control device for generating a defined pretensioning of the engagement; and driving the worm shaft as a function of the control device at a defined rotational speed for a determined period of time.
    Type: Grant
    Filed: December 11, 2014
    Date of Patent: April 16, 2019
    Assignees: THYSSENKRUPP PRESTA AG, THYSSENKRUPP AG
    Inventors: Joseph-Léon Strobel, Paul Schwarzhans
  • Patent number: 10150809
    Abstract: Disclosed herein is a method for identifying TREM-1's ligand and antibodies, or fragments thereof, which are capable of modifying the function of TREM-1's ligand. Antibodies that reduce or block TREM-1 activation may be identified and selected using this method. Antibodies that bind to TREM-1's ligand and reduce TREM-1 activity may be suitable for use as medicaments.
    Type: Grant
    Filed: April 10, 2017
    Date of Patent: December 11, 2018
    Assignee: Bristol-Myers Squibb Company
    Inventors: Vibeke Westphal Stennicke, Christine Brender Read, Joseph Leon Kuijper, Xiaoting Tang, Mark Heipel, Siv Annegrethe Hjorth
  • Publication number: 20180346584
    Abstract: Novel polypeptide combinations, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor17-containing multimeric or heterodimer cytokine receptors that may be used as novel cytokine antagonists, and within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. The present invention also includes methods for producing the multimeric or heterodimeric cytokine receptor, uses therefor and antibodies thereto.
    Type: Application
    Filed: August 10, 2018
    Publication date: December 6, 2018
    Inventors: Cindy A. Sprecher, Joseph Leon Kuijper, Maria M. Dasovich, Francis J. Grant, Theodore E. Whitmore, Angela K. Hammond, Julia E. Novak, Jane A. Gross, Stacey R. Dillon
  • Patent number: 10137926
    Abstract: A steering shaft for a motor vehicle steering system may be used in connection with a variety of power assistance mechanisms. The steering shaft may comprise a first shaft part and a second shaft part that are rotationally-elastically coupled by way of a torsion bar. In order to transmit torque, the torsion bar may be received in a bore of the first shaft part and coupled to both the first and second shaft parts. In many cases, a first end of the torsion bar is coupled to the first shaft part, and a second end of the torsion bar is coupled to the second shaft part. The torsion bar may be mounted in the bore such that it can be rotated with respect to the first shaft part via a bearing element. In some examples, the bearing element comprises a prestressing element.
    Type: Grant
    Filed: February 25, 2015
    Date of Patent: November 27, 2018
    Assignees: THYSSENKRUPP PRESTA AG, THYSSENKRUPP AG
    Inventor: Joseph Léon Strobel
  • Publication number: 20180300606
    Abstract: A deep neural network (“DNN”) module can compress and decompress neuron-generated activation data to reduce the utilization of memory bus bandwidth. The compression unit can receive an uncompressed chunk of data generated by a neuron in the DNN module. The compression unit generates a mask portion and a data portion of a compressed output chunk. The mask portion encodes the presence and location of the zero and non-zero bytes in the uncompressed chunk of data. The data portion stores truncated non-zero bytes from the uncompressed chunk of data. A decompression unit can receive a compressed chunk of data from memory in the DNN processor or memory of an application host. The decompression unit decompresses the compressed chunk of data using the mask portion and the data portion. This can reduce memory bus utilization, allow a DNN module to complete processing operations more quickly, and reduce power consumption.
    Type: Application
    Filed: April 13, 2018
    Publication date: October 18, 2018
    Inventors: Joseph Leon CORKERY, Benjamin Eliot LUNDELL, Larry Marvin WALL, Chad Balling McBRIDE, Amol Ashok AMBARDEKAR, George PETRE, Kent D. CEDOLA, Boris BOBROV
  • Publication number: 20180016326
    Abstract: Disclosed herein is a method for identifying TREM-1's ligand and antibodies, or fragments thereof, which are capable of modifying the function of TREM-1's ligand. Antibodies that reduce or block TREM-1 activation may be identified and selected using this method. Antibodies that bind to TREM-1's ligand and reduce TREM-1 activity may be suitable for use as medicaments.
    Type: Application
    Filed: April 10, 2017
    Publication date: January 18, 2018
    Inventors: Vibeke Westphal STENNICKE, Christine Brender Read, Joseph Leon Kuijper, Xiaoting Tang, Mark Heipel, Siv Annegrethe Hjorth
  • Publication number: 20170369580
    Abstract: Novel polypeptide combinations, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor17-containing multimeric or heterodimer cytokine receptors that may be used as novel cytokine antagonists, and within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. The present invention also includes methods for producing the multimeric or heterodimeric cytokine receptor, uses therefor and antibodies thereto.
    Type: Application
    Filed: September 11, 2017
    Publication date: December 28, 2017
    Inventors: Cindy A. Sprecher, Joseph Leon Kuijper, Maria M. Dasovich, Francis J. Grant, Theodore E. Whitmore, Angela K. Hammond, Julia E. Novak, Jane A Gross, Stacey R. Dillon
  • Patent number: 9663568
    Abstract: Disclosed herein is a method for identifying TREM-1's ligand and antibodies, or fragments thereof, which are capable of modifying the function of TREM-1's ligand. Antibodies that reduce or block TREM-1 activation may be identified and selected using this method. Antibodies that bind to TREM-1's ligand and reduce TREM-1 activity may be suitable for use as medicaments.
    Type: Grant
    Filed: November 30, 2012
    Date of Patent: May 30, 2017
    Assignee: Novo Nordisk A/S
    Inventors: Vibeke Westphal Stennicke, Christine Brender Read, Joseph Leon Kuijper, Xiaoting Tang, Mark Heipel, Siv Annegrethe Hjorth
  • Publication number: 20170072988
    Abstract: A steering shaft for a motor vehicle steering system may be used in connection with a variety of power assistance mechanisms. The steering shaft may comprise a first shaft part and a second shaft part that are rotationally-elastically coupled by way of a torsion bar. In order to transmit torque, the torsion bar may be received in a bore of the first shaft part and coupled to both the first and second shaft parts. In many cases, a first end of the torsion bar is coupled to the first shaft part, and a second end of the torsion bar is coupled to the second shaft part. The torsion bar may be mounted in the bore such that it can be rotated with respect to the first shaft part via a bearing element. In some examples, the bearing element comprises a prestressing element.
    Type: Application
    Filed: February 25, 2015
    Publication date: March 16, 2017
    Applicants: ThyssenKrupp Presta AG, ThyssenKrupp AG
    Inventor: Joseph Léon STROBEL
  • Publication number: 20160341304
    Abstract: One method for running in a worm gear of an electromechanical steering system may comprise preparing the electromechanical servo steering system in a preassembled state in which one end of a worm shaft close to a motor or an end remote from the motor is mounted rotatably in a bearing in the gear housing and the respective other end of the worm shaft is movable in a radial direction so as to form a free end; rotatably mounting the free end of the worm shaft in an adjustable pretensioning device that is configured to pretension the worm shaft in a direction of the worm wheel in the engagement; adjusting the pretensioning device by way of a control device for generating a defined pretensioning of the engagement; and driving the worm shaft as a function of the control device at a defined rotational speed for a determined period of time.
    Type: Application
    Filed: December 11, 2014
    Publication date: November 24, 2016
    Applicants: ThyssenKrupp Presta AG, ThyssenKrupp AG
    Inventors: Joseph-Léon STROBEL, Paul SCHWARZHANS