Abstract: A membrane-based separation device comprises multiple interconnected flat sheets of membrane bonded to a flexible film. The bonded films are bonded in a way to create an accordion or zig-zag shape. In certain embodiments, the first or upstream layer is affixed to a suitable housing, and the last or most downstream layer is also affixed to the suitable housing. The housing may contain an inlet port for the introduction of sample, and an outlet port for the removal of filtered sample. Flow through the segments is in parallel. Since the membranes are not folded or pleated, higher performance membranes (e.g., polysulfone based membranes with some degree of asymmetry) than those usable in pleated or folded systems can be used.

Abstract: A filtration cartridge is provided comprising one or a stack of filtration units sealed to each other at their inner periphery and their outer periphery and to end caps thereby eliminating the need for a housing surrounding the stack. Fluid pathways are provided so that filtration of all incoming feed is assured prior to passing from the cartridge as filtrate.

Abstract: A sterile to sterile connection device comprising a connector and one or more coupling devices. The connector has body portion which has two openings sealed from the environment so as to form a sterile environment within the connector. At least one of the openings being sealed from the environment by a sterile barrier plug. The connector also has a port capable movement within the body of the connector to at least an open and a closed position. The coupling device is formed of a body having two openings and a stem having a bore through at least a portion of the stem. The stem is contained within the body and capable of moving at least linearly through the body between a first and second stem position. One of the openings of the stem is sealed from the environment by a sterile barrier plug and the other is sealed to a presterilized component. The coupling device opening containing the sterile barrier plug is attached to either the inlet or outlet of the connector.

Abstract: The present invention relates to a stand for holding disposable filter capsules and is formed of three or more legs, a base above the legs and to which the leg as are attached and three or more arms that are attached to an opposite surface of the base from that of the legs. The arms and legs have at least curved or angled portion that allows for the arms and legs to spread out from the diameter of the base. Preferably, the arms have a second curved or angled portion that then allows the upper portion of the arms to become substantially vertical.

Abstract: The present invention relates to a stand for holding disposable filter capsules and is formed of three or more legs, a base above the legs and to which the leg as are attached and three or more arms that are attached to an opposite surface of the base from that of the legs. The arms and legs have at least curved or angled portion that allows for the arms and legs to spread out from the diameter of the base. Preferably, the arms have a second curved or angled portion that then allows the upper portion of the arms to become substantially vertical.

Abstract: A seal, a vent for a filter housing and a system for using them. The seal is designed a first outer seal having a closed outer periphery that divides and isolates a first inner area from the outside environment and a second inner seal formed along a portion of the inner surface of the first outer seal and forming a second inner area within the first inner area and which is isolated from both the first inner area and the outside environment. The seal is incorporated into a vent for a filter housing having opening is contained within a vent area and the opening is offset from the center of the vent area. The opening establishes a fluid pathway from the interior to the exterior of the filter device. The inner seal surrounds the vent opening. The outer seal also surrounds the vent opening at one of its ends and surrounds the entire periphery of the vent area so as to isolate the vent area from the area outside of the vent area.