Patents by Inventor Joseph M. Carroll

Joseph M. Carroll has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of interleukin-11 to prevent immune-mediated cytotoxicity
    Publication number: 20010051600
    Abstract: The use of interleukin-11 to prevent, to ameliorate, and to treat an immune-mediated disease in a mammal in need of such treatment is disclosed.
    Type: Application
    Filed: March 9, 2000
    Publication date: December 13, 2001
    Inventors: James Keith, Joseph M. Carroll, Jordan S. Pober
  • Transgenic animals as model of psoriasis
    Patent number: 6187993
    Abstract: A nucleic acid construct comprising a promoter capable of directing expression in the suprabasal cells of the epidermis and means to cause expression of an integrin subunit in the suprabasal cells. Preferably the means to cause expression of an integrin subunit is an integrin subunit coding sequence. A transgenic animal which expresses an &agr; subunit and a &bgr; subunit of integrin in the suprabasal cells of the epidermis and methods for making the transgenic animals. At least some of the transgenic animals are useful models of human disease, especially psoriasis. A method of treating psoriasis comprising administering to the patient a compound which modulates integrin function.
    Type: Grant
    Filed: November 3, 1997
    Date of Patent: February 13, 2001
    Assignee: Imperial Cancer Research Technology Limited
    Inventors: Fiona M. Watt, Joseph M. Carroll