Abstract: A hypodermic syringe assembly includes a barrel having an open proximal end, a chamber for retaining fluid and a tip portion extending from a distal end of the barrel having a passageway therethrough communicating with the chamber. A needle cannula having a distal end extends outwardly from the tip portion and includes a lumen in fluid communication with the passageway. A needle shield assembly includes a resilient needle sheath having an open proximal end, a closed distal end, a sidewall defining a receptacle therein and is positioned within an elongate rigid shield having an open proximal end, a distal end and a sidewall therebetween. Structure for holding the sheath within the shield is provided so that the sheath cannot be removed from the shield during normal use of the syringe assembly. The sheath includes cannula sealing means at the distal end of the receptacle.

Abstract: A two-component syringe assembly includes an elongate barrel having a chamber for retaining fluid and a distal end having a passageway therethrough communicating with the chamber. A bypass stopper is slidably positioned in fluid-tight engagement inside the barrel. The barrel also includes a bypass defining a bypass zone positioned along the barrel for allowing fluid to flow around the bypass stopper when the bypass stopper is positioned intermediate the ends of the barrel in the bypass zone. A stopper is slidably positioned in fluid-tight engagement inside the barrel. A rigid plunger rod having an elongate body portion engages the stopper to facilitate its operation. A barrier flange is positioned on the body portion and intermediate the ends thereof.

Abstract: A syringe package includes a hollow barrel and a slidable plunger inside the barrel extending out of its proximal end. A needle cannula extends from a distal end of the barrel. A shield covers the cannula and is connected to the barrel to provide a seal thereto. The shield has a frangible portion adapted to be ruptured so that a first portion of the shield is removable and a second portion remains connected to the barrel as evidence of a broken seal. A cap covers the proximal end of the plunger and is connected to the barrel to provide a seal. The cap has a frangible portion adapted to be ruptured so that a first portion of the cap is removable and a second portion is adapted to remain connected to the barrel as evidence of a broken seal at this end of the syringe.