Abstract: Systems and methods for high bandwidth control of thrust response for turbofan or turboprop engines are provided. Such systems and methods include an engine control system that processes a rate command and a feedback signal from an engine to generate separate fuel and electric machine control signals that respectively control fuel and electric machine dynamics of the engine to produce engine dynamics that result in desired thrust response.

Abstract: The present disclosure provides PROTAC compounds represented by Formula (A): D-L-DSM (A), or an enantiomer, a diastereoisomer, and/or a pharmaceutically acceptable salt of any one of the foregoing, wherein: DSM is a degradation signaling compound {e.g., an E3 ubiquitin ligase recruitment ligand, such as a CRBN ligand or a VHL ligand) covalently attached to a linker L; L is a linker that covalently attaches DSM to D; and D is a Bcl-xL inhibitor compound of Formula (I) or Formula (II) covalently attached to the linker L: (I); (II) wherein the definitions for the variables are described herein. Also provided are pharmaceutical compositions comprising the PROTAC compounds of the present disclosure and methods of use and methods of making thereof.

Abstract: Data is received that identifies a medication comprising a concentration of a drug product in a background fluid and a composition of a surface of a receptacle for housing the medication. Thereafter, a drug substance adsorption behavior model executed by at least one computing device is used to predict a percent of dose lost and an interaction behavior between the medication and the receptacle. Thereafter, data is provided that characterizes the predicted percent of dose lost and the interaction behavior. The drug substance adsorption behavior model can be informed using quartz crystal microbalance (QCM) sensors that are exposed to medications and are coated with materials designed to mimic exemplary receptacles. Related apparatus, systems, techniques, and articles are also described.

Abstract: Shrimp processing apparatus to peel shrimp along with methods for peeling shrimp are described herein. The shrimp processing apparatus may be provided in systems including one or more processing stations configured to peel individual shrimp, where peeling may involve removal of shell segments on the dorsal surfaces of the shrimp abdomen and/or removal of pleopods/swimmerets on the ventral surfaces of the shrimp abdomen and, optionally, separation of shell segments. The processing systems and methods may, in one or more embodiments, include apparatus for and methods of measuring the shrimp.

Abstract: Systems and methods for high bandwidth control of thrust response for turbofan or turboprop engines are provided. Such systems and methods include an engine control system that processes a rate command and a feedback signal from an engine to generate separate fuel and electric machine control signals that respectively control fuel and electric machine dynamics of the engine to produce engine dynamics that result in desired thrust response.

Abstract: A smart leash system is disclosed, which includes a handheld system configured to be held by a user, a harness system configured to be worn by an animal, a leash coupled to and extended between the handheld system and the harness system, and a load measuring sensor coupled to the handheld system and configured to measure force applied to the leash, wherein one of the handheld system, the harness system, and both the handheld system and the harness system is configured to receive a force signal representing the force applied to the leash and signal the harness system to provide a feedback to the animal when the force exceeds a predetermined threshold.

Abstract: A smart leash system is disclosed, which includes a handheld system configured to be held by a user, a collar system configured to be worn by an animal, a leash coupled to and extended between the handheld system and the collar system, and a load measuring sensor coupled to the handheld system and configured to measure force applied to the leash, wherein one of the handheld system, the collar system, and both the handheld system and the collar system is configured to receive a force signal representing the force applied to the leash and signal the collar system to provide a feedback to the animal when the force exceeds a predetermined threshold.

Abstract: Consent management between a client and a network server. In response to a request for consent, a central server determines if requested user information is included in a user profile associated with a user and if the user has granted consent to share the requested user information. A user interface is provided to the user via a browser of the client to collect the requested user information that is not included in the user profile and the consent to share the requested user information from the user. After receiving the user information provided by the user via the user interface, the service provided by the network server is allowed access to the received user information, and the central server updates the user profile. Other aspects of the invention are directed to computer-readable media for use with profile and consent accrual.

Abstract: Pellet compositions for sealing a leak include (a) a fibrillated fibrous material, (b) a particulate material, and (c) a compound that by itself and/or in combination with at least one additional compound is configured to generate effervescence. Systems for sealing a leak include (a) a pellet composition, and (b) a first fluid configured for combination with the pellet composition, wherein the first fluid includes water. Methods for sealing a leak in a heat exchange system are described.

Abstract: Pellet compositions for sealing a leak include (a) a fibrillated fibrous material, (b) a particulate material, and (c) a compound that by itself and/or in combination with at least one additional compound is configured to generate effervescence. Systems for sealing a leak include (a) a pellet composition, and (b) a first fluid configured for combination with the pellet composition, wherein the first fluid includes water. Methods for sealing a leak in a heat exchange system are described.

Abstract: Pellet compositions for sealing a leak include (a) a fibrillated fibrous material, (b) a particulate material, and (c) a compound that by itself and/or in combination with at least one additional compound is configured to generate effervescence. Systems for sealing a leak include (a) a pellet composition, and (b) a first fluid configured for combination with the pellet composition, wherein the first fluid includes water. Methods for sealing a leak in a heat exchange system are described.

Abstract: Pellet compositions for sealing a leak include (a) a fibrillated fibrous material, (b) a particulate material, and (c) a compound that by itself and/or in combination with at least one additional compound is configured to generate effervescence. Systems for sealing a leak include (a) a pellet composition, and (b) a first fluid configured for combination with the pellet composition, wherein the first fluid includes water. Methods for sealing a leak in a heat exchange system are described.

Abstract: Consent management between a client and a network server. In response to a request for consent, a central server determines if requested user information is included in a user profile associated with a user and if the user has granted consent to share the requested user information. A user interface is provided to the user via a browser of the client to collect the requested user information that is not included in the user profile and the consent to share the requested user information from the user. After receiving the user information provided by the user via the user interface, the service provided by the network server is allowed access to the received user information, and the central server updates the user profile. Other aspects of the invention are directed to computer-readable media for use with profile and consent accrual.

Abstract: Consent management between a client and a network server. In response to a request for consent, a central server determines if requested user information is included in a user profile associated with a user and if the user has granted consent to share the requested user information. A user interface is provided to the user via a browser of the client to collect the requested user information that is not included in the user profile and the consent to share the requested user information from the user. After receiving the user information provided by the user via the user interface, the service provided by the network server is allowed access to the received user information, and the central server updates the user profile. Other aspects of the invention are directed to computer-readable media for use with profile and consent accrual.

Abstract: Consent management between a client and a network server. In response to a request for consent, a central server determines if requested user information is included in a user profile associated with a user and if the user has granted consent to share the requested user information. A user interface is provided to the user via a browser of the client to collect the requested user information that is not included in the user profile and the consent to share the requested user information from the user. After receiving the user information provided by the user via the user interface, the service provided by the network server is allowed access to the received user information, and the central server updates the user profile. Other aspects of the invention are directed to computer-readable media for use with profile and consent accrual.

Abstract: Consent management between a client and a network server. In response to a request for consent, a central server determines if requested user information is included in a user profile associated with a user and if the user has granted consent to share the requested user information. A user interface is provided to the user via a browser of the client to collect the requested user information that is not included in the user profile and the consent to share the requested user information from the user. After receiving the user information provided by the user via the user interface, the service provided by the network server is allowed access to the received user information, and the central server updates the user profile. Other aspects of the invention are directed to computer-readable media for use with profile and consent accrual.

Abstract: A governor configured to regulate the rotational velocity of one or more rotors of an aircraft by adjusting a collective blade pitch of the one or more rotors. In one embodiment, the governor comprises a control monitor, a maximum pitch module, a rotor module, and a pitch adjustment module. The control monitor is configured to monitor one or more flight control inputs that are controllable by an operator of the aircraft. The maximum pitch module is configured to dynamically determine a maximum collective blade pitch based on the one or more flight control inputs monitored by the control monitor. The rotor module is configured to monitor information related to the rotational velocity of the one or more rotors. The pitch adjustment module is configured to (i) receive information related to the rotational velocity of the one or more rotors from the rotor module and (ii) adjust the collective blade pitch of the one or more rotors to regulate the rotational velocity of the one or more rotors.

Abstract: Providing access to a resource via authorization data that conditionally defines the access by an expression that identifies the resource by name and by at least one property of the resource. An authorization service issues the authorization data (e.g., as a token) and evaluating authorization data received from a client. The authorization service evaluates the expression in the authorization data to identify the resource and determine the rights associated with the user for the resource. The authorization service implements role-based access control to control access to resources in a distributed, multi-site network.