Patents by Inventor Joseph Matthew Colacino

Joseph Matthew Colacino has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antiviral method of use
    Publication number: 20040067965
    Abstract: The present invention provides a method for treating HCMV in a human requiring said treatment, which comprises administering to said human an effective amount of ALIMTA.
    Type: Application
    Filed: July 25, 2003
    Publication date: April 8, 2004
    Inventors: Douglas Wayne Balogh, Joseph Matthew Colacino
  • Phosphonate nucleotide and thiadiazole compounds for the treatment of smallpox
    Publication number: 20040023928
    Abstract: The present invention provides methods of treating smallpox and other poxvirus infections with a pharmaceutically effective amount of LY582563 or LY217896.
    Type: Application
    Filed: October 17, 2002
    Publication date: February 5, 2004
    Inventor: Joseph Matthew Colacino
  • Inhibition of viral replication
    Patent number: 6037348
    Abstract: The present invention provides a method of inhibiting influenza and flaviviral replication based on a mechanism of action in which HA-mediated fusion or E protein mediated fusion is inhibited by a fusion inhibiting agent which binds, complexes or otherwise becomes associated with HA or E protein during the translation of the target protein and/or its vesicular transport.
    Type: Grant
    Filed: February 5, 1997
    Date of Patent: March 14, 2000
    Assignee: Eli Lilly and Company
    Inventors: Joseph Matthew Colacino, Steven Duane Hatch, William Joseph Hornback, Mark Ayer Muesing, John Edwin Munroe, Kirk Alan Staschke, Joseph Chiou-Chung Tang
  • Anti-viral compound
    Patent number: 5891874
    Abstract: A series of benzimidazole compounds having the following general structure are provided which inhibit the growth of picornaviruses (e.g., rhinoviruses, enteroviruses, polioviruses, coxsackieviruses of the A and B groups, echo virus and Mengo virus) and flaviviruses (e.g., hepatitis C and bovine diarrheal virus). ##STR1## A method for inhibiting picornaviruses and flaviviruses is also provided which includes administering to a host an effective amount of the inventive benzimidazole compounds.
    Type: Grant
    Filed: June 4, 1997
    Date of Patent: April 6, 1999
    Assignee: Eli Lilly and Company
    Inventors: Joseph Matthew Colacino, Beverly Ann Heinz, Louis Nickolaus Jungheim, Shawn Christopher Miller, Wayne Alfred Spitzer, Joseph Chiou-chung Tang, Mark Joseph Tebbe, Frantz Victor
  • Anti-viral compounds
    Patent number: 5821242
    Abstract: The present application provides a series of benzimidazole compounds which inhibit the growth of picornaviruses, such as rhinoviruses, enteroviruses, polioviruses, coxsackieviruses of the A and B groups, echo virus and Mengo virus and flaviviruses such as hepatitis C and bovine diarrheal virus.
    Type: Grant
    Filed: June 4, 1997
    Date of Patent: October 13, 1998
    Assignee: Eli Lilly and Company
    Inventors: Joseph Matthew Colacino, Beverly Ann Heinz, Louis Nickolaus Jungheim, Shawn Christopher Miller, Wayne Alfred Spitzer, Joseph Chiou-chung Tang, Mark Joseph Tebbe, Frantz Victor