Patents by Inventor Joseph MCNULTY

Joseph MCNULTY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROTEIN TYROSINE PHOSPHATASE INHIBITORS
    Publication number: 20250066357
    Abstract: Compounds of Formula I or a stereoisomer, tautomer, prodrug or pharmaceutically acceptable salt thereof are provided, which are useful for the treatment of hyperproliferative diseases.
    Type: Application
    Filed: November 13, 2024
    Publication date: February 27, 2025
    Applicant: Array BioPharma Inc.
    Inventors: James Francis BLAKE, Mark Laurence BOYS, Mark Joseph CHICARELLI, Adam Wade COOK, Mohamed S.A. ELSAYED, Jay Bradford FELL, John Peter FISCHER, Ronald Jay HINKLIN, Oren Teague MCNULTY, Macedonio J. MEJIA, Martha E. RODRIGUEZ, Christina Elizabeth WONG
  • THYMIDINE KINASE GENE
    Publication number: 20220401581
    Abstract: Nucleic acid sequences encoding improved Herpes Simplex Virus Thymidine Kinases are provided, including their use in diagnostic and therapeutic applications. The thymidine kinases may be mutated using conservative mutations, non-conservative mutations, or both. Also provided are gene therapeutic systems, including viral and retroviral particles.
    Type: Application
    Filed: June 17, 2022
    Publication date: December 22, 2022
    Inventors: John P. LEVY, Rebecca A. REED, Joseph McNULTY, Robert G. JOHNSON, JR.
  • Thymidine kinase gene
    Patent number: 11364307
    Abstract: Nucleic acid sequences encoding improved Herpes Simplex Virus Thymidine Kinases are provided, including their use in diagnostic and therapeutic applications. The thymidine kinases may be mutated using conservative mutations, non-conservative mutations, or both. Also provided are gene therapeutic systems, including viral and retroviral particles.
    Type: Grant
    Filed: February 21, 2020
    Date of Patent: June 21, 2022
    Assignee: GENVIVO, INC.
    Inventors: John P. Levy, Rebecca A Reed, Joseph McNulty, Robert G. Johnson, Jr.
  • Thymidine kinase diagnostic assay for gene therapy applications
    Patent number: 11253611
    Abstract: Nucleic acid sequences encoding improved Herpes Simplex Virus Thymidine Kinases are provided, including their use in diagnostic and therapeutic applications. The thymidine kinases may be mutated using conservative mutations, non-conservative mutations, or both. Also provided are gene therapeutic systems, including viral and retroviral particles.
    Type: Grant
    Filed: July 12, 2019
    Date of Patent: February 22, 2022
    Assignee: GENVIVO, INC.
    Inventors: John P. Levy, Rebecca A. Reed, Joseph McNulty, Robert G. Johnson, Jr.
  • THYMIDINE KINASE GENE
    Publication number: 20200179533
    Abstract: Nucleic acid sequences encoding improved Herpes Simplex Virus Thymidine Kinases are provided, including their use in diagnostic and therapeutic applications. The thymidine kinases may be mutated using conservative mutations, non-conservative mutations, or both. Also provided are gene therapeutic systems, including viral and retroviral particles.
    Type: Application
    Filed: February 21, 2020
    Publication date: June 11, 2020
    Inventors: John P. LEVY, Rebecca A. REED, Joseph McNULTY, Robert G. JOHNSON
  • Thymidine kinase gene
    Patent number: 10610603
    Abstract: Nucleic acid sequences encoding improved Herpes Simplex Virus Thymidine Kinases are provided, including their use in diagnostic and therapeutic applications. The thymidine kinases may be mutated using conservative mutations, non-conservative mutations, or both. Also provided are gene therapeutic systems, including viral and retroviral particles.
    Type: Grant
    Filed: February 8, 2018
    Date of Patent: April 7, 2020
    Assignee: GenVivo, Inc.
    Inventors: John P. Levy, Rebecca A. Reed, Joseph McNulty, Robert G. Johnson, Jr.
  • THYMIDINE KINASE DIAGNOSTIC ASSAY FOR GENE THERAPY APPLICATIONS
    Publication number: 20190328904
    Abstract: Nucleic acid sequences encoding improved Herpes Simplex Virus Thymidine Kinases are provided, including their use in diagnostic and therapeutic applications. The thymidine kinases may be mutated using conservative mutations, non-conservative mutations, or both. Also provided are gene therapeutic systems, including viral and retroviral particles.
    Type: Application
    Filed: July 12, 2019
    Publication date: October 31, 2019
    Inventors: John P. LEVY, Rebecca A. REED, Joseph MCNULTY, Robert G. JOHNSON, Jr.
  • Thymidine kinase diagnostic assay for gene therapy applications
    Patent number: 10350302
    Abstract: Nucleic acid sequences encoding improved Herpes Simplex Virus Thymidine Kinases are provided, including their use in diagnostic and therapeutic applications. The thymidine kinases may be mutated using conservative mutations, non-conservative mutations, or both. Also provided are gene therapeutic systems, including viral and retroviral particles.
    Type: Grant
    Filed: May 31, 2018
    Date of Patent: July 16, 2019
    Assignee: GenVivo, Inc.
    Inventors: John P. Levy, Rebecca A. Reed, Joseph McNulty, Robert G. Johnson, Jr.
  • THYMIDINE KINASE DIAGNOSTIC ASSAY FOR GENE THERAPY APPLICATIONS
    Publication number: 20180264137
    Abstract: Nucleic acid sequences encoding improved Herpes Simplex Virus Thymidine Kinases are provided, including their use in diagnostic and therapeutic applications. The thymidine kinases may be mutated using conservative mutations, non-conservative mutations, or both. Also provided are gene therapeutic systems, including viral and retroviral particles.
    Type: Application
    Filed: May 31, 2018
    Publication date: September 20, 2018
    Inventors: John P. LEVY, Rebecca A. REED, Joseph MCNULTY, Robert G. JOHNSON, JR.
  • THYMIDINE KINASE GENE
    Publication number: 20180236101
    Abstract: Nucleic acid sequences encoding improved Herpes Simplex Virus Thymidine Kinases are provided, including their use in diagnostic and therapeutic applications. The thymidine kinases may be mutated using conservative mutations, non-conservative mutations, or both. Also provided are gene therapeutic systems, including viral and retroviral particles.
    Type: Application
    Filed: February 8, 2018
    Publication date: August 23, 2018
    Inventors: John P. LEVY, Rebecca A. REED, Joseph McNULTY, Robert G. JOHNSON, Jr.
  • Method for identifying and treating a patient having tumor lesions comprising administering a gene therapy retroviral vector particle comprising a mutated HSV-thymidine kinase (HSV-TK) polynucleotide
    Patent number: 9999683
    Abstract: Nucleic acid sequences encoding improved Herpes Simplex Virus Thymidine Kinases are provided, including their use in diagnostic and therapeutic applications. The thymidine kinases may be mutated using conservative mutations, non-conservative mutations, or both. Also provided are gene therapeutic systems, including viral and retroviral particles.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: June 19, 2018
    Assignee: EPEIUS BIOTECHNOLOGIES CORPORATION
    Inventors: John P. Levy, Rebecca A. Reed, Joseph McNulty, Robert G. Johnson, Jr.
  • Thymidine kinase gene
    Patent number: 9925276
    Abstract: Nucleic acid sequences encoding improved Herpes Simplex Virus Thymidine Kinases are provided, including their use in diagnostic and therapeutic applications. The thymidine kinases may be mutated using conservative mutations, non-conservative mutations, or both. Also provided are gene therapeutic systems, including viral and retroviral particles.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: March 27, 2018
    Assignee: EPEIUS BIOTECHNOLOGIES CORPORATION
    Inventors: John P. Levy, Rebecca A. Reed, Joseph McNulty, Robert G. Johnson, Jr.
  • THYMIDINE KINASE DIAGNOSTIC ASSAY FOR GENE THERAPY APPLICATIONS
    Publication number: 20140294772
    Abstract: Nucleic acid sequences encoding improved Herpes Simplex Virus Thymidine Kinases are provided, including their use in diagnostic and therapeutic applications. The thymidine kinases may be mutated using conservative mutations, non-conservative mutations, or both. Also provided are gene therapeutic systems, including viral and retroviral particles.
    Type: Application
    Filed: March 14, 2014
    Publication date: October 2, 2014
    Applicant: Epeius Biotechnologies Corporation
    Inventors: John P. LEVY, Rebecca A. REED, Joseph MCNULTY, Robert G. JOHNSON, JR.
  • THYMIDINE KINASE GENE
    Publication number: 20140288163
    Abstract: Nucleic acid sequences encoding improved Herpes Simplex Virus Thymidine Kinases are provided, including their use in diagnostic and therapeutic applications. The thymidine kinases may be mutated using conservative mutations, non-conservative mutations, or both. Also provided are gene therapeutic systems, including viral and retroviral particles.
    Type: Application
    Filed: March 14, 2014
    Publication date: September 25, 2014
    Inventors: John P. LEVY, Rebecca A. REED, Joseph MCNULTY, Robert G. JOHNSON, JR.