Patents by Inventor Joseph Milano

Joseph Milano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for the recombination of genetic elements
    Patent number: 7879582
    Abstract: A method for the recombination of a gene is disclosed. The method involves the design of unpaired forward and reverse primers having homology to the 5? end of one template and to the 3? end of another template. Short primer extension periods results in a recombined template having paired 5? and 3? ends that can then be amplified. The amplified sample is devoid of any parental template.
    Type: Grant
    Filed: February 26, 2003
    Date of Patent: February 1, 2011
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: Joseph Milano, Xiao-Song Tang
  • Biomarker Detection Assays
    Publication number: 20090253126
    Abstract: A method for identifying compounds capable of modulating the Notch pathway. The test compound is either administered to an animal or is brought into contact with a cell in culture, after which the expression of the basic helix-loop-helix transcription factor Math1 in a sample from said animal or cell is directed. A change in Math1 expression in the presence of said test compound as compared to in the absence of said compound indicates that said compound modulates the Notch pathway.
    Type: Application
    Filed: February 21, 2005
    Publication date: October 8, 2009
    Applicant: ASTRAZENECA AB
    Inventors: Paul Ciaccio, Joseph Milano, Francois Pognan
  • Method for the recombination of genetic elements
    Publication number: 20040014085
    Abstract: A method for the recombination of a gene is disclosed. The method involves the design of unpaired forward and reverse primers having homology to the 5′ end of one template and to the 3′ end of another template. Short primer extension periods results in a recombined template having paired 5′ and 3′ ends that can then be amplified. The amplified sample is devoid of any parental template.
    Type: Application
    Filed: February 26, 2003
    Publication date: January 22, 2004
    Inventors: Joseph Milano, Xiao-Song Tang