Abstract: Electrical connectors and assemblies may include a housing and a contact member therein. The contact member includes electrical contacts. A contact barrier is connected to the housing and movable between a closed state and an open state. In the open state, the contact member is exposed and, in the closed state, the contact member is protected by the contact barrier. The contact barrier is biased into the closed state. Electrical connectors and assemblies may include a housing with a core assembly having at least one electrical contact. A rotatable coupling member is rotatably attached to an end of the housing and includes a coupling housing, at least one latching element coupled to an inner surface of the coupling housing, and at least one center biasing element configured to bias and self-center the rotatable coupling member relative to the housing into a ready-to-connect orientation.

Abstract: Optical interlayers, laminated composites and improved methods for manufacturing the optical interlayers and laminated composites are provided. An optical interlayer film comprises at least one surface having an embossed surface pattern having at least two channels extending in at least two non-parallel directions. The channels have a depth of greater than about 20 ?m. The surface pattern allows for the removal of air between the interlayer and the outer laminate sheets, thereby establishing the requisite seal therebetween while minimizing premature edge sealing. The laminated composites are particularly useful for safety glazing in a variety of applications, such as automobiles, airplanes, trains, or other modes of transportation, display devices, windows in homes and other buildings, building facades, cabinets, and/or weight bearing architectural structures such as stairs and floors.

Abstract: Optical interlayers, laminated composites and improved methods for manufacturing the optical interlayers and laminated composites are provided. An optical interlayer film comprises at least one surface having an embossed surface pattern having at least two channels extending in at least two non-parallel directions. The channels have a depth of greater than about 20 ?m. The surface pattern allows for the removal of air between the interlayer and the outer laminate sheets, thereby establishing the requisite seal therebetween while minimizing premature edge sealing. The laminated composites are particularly useful for safety glazing in a variety of applications, such as automobiles, airplanes, trains, or other modes of transportation, display devices, windows in homes and other buildings, building facades, cabinets, and/or weight bearing architectural structures such as stairs and floors.

Abstract: An intraocular lens (31) which may be used as a posterior lens in a lens train including a converging anterior lens (20) and diverging posterior lens (31) in which the optical/focal axes of the two lenses are not coincident such that the focal point (9) of the lens train is offset from the focal axis of the anterior lens. Light rays (50) incident upon the anterior lens parallel to its focal axis may thus be directed (51) to parts of the retina offset from the fovea where the macula may not have degenerated.

Abstract: An intraocular lens (31) which may be used as a posterior lens in a lens train including a converging anterior lens (20) and diverging posterior lens (31) in which the optical/focal axes of the two lenses are not coincident such that the focal point (9) of the lens train is offset from the focal axis of the anterior lens. Light rays (50) incident upon the anterior lens parallel to its focal axis may thus be directed (51) to parts of the retina offset from the fovea where the macula may not have degenerated.

Abstract: Described herein are fertilizers for enhancing the carbon sequestration properties of soil. The fertilizers described herein include algae comprising algaenan. In one aspect, the fertilizer includes (a) one or more organic nitrogen sources, (b) one or more synthetic nitrogen sources, and (c) algae comprising algaenan. The fertilizers and fertilizer compositions release nitrogen at a predictable rate over time, which can enhance growth of plants that are fertile with the composition described herein.

Abstract: N-heterocyclic compounds that block cytokine production via inhibition of p38 kinase are disclosed. In one embodiment, compounds of the present invention are represented by Formula I: Methods of production, pharmaceutical compositions and methods of treating conditions associated with inappropriate p38 kinase activity or TNF-? expression utilizing compounds of the present invention are also disclosed.

Abstract: This invention is directed to physiologically active compounds of formula (I) wherein represents a bicyclic ring system, of about 10 to about 13 ring members, in which the ring is an azaheterocycle, and the ring represents an azaheteroaryl ring, or an optionally halo substituted benzene ring; and N-oxides thereof, and pharmaceutically acceptable salts of the compounds of formula (I) and N-oxides thereof, Such compounds inhibit the production or physiological effects of TNF and inhibit cyclic AMP phosphodiesterase. The invention is also directed to pharmnaceutical compositions comprising compoundS of formula (I), their phatmaceUtical use and methods for their preparation.

Abstract: Compounds that selectively inhibit the binding of ligands to ?4?1 integrin (VLA-4) and methods for their preparation are disclosed. In one embodiment, compounds of the invention are represented by Formula I: As selective inhibitors of VLA-4 mediated cell adhesion, compounds of the present invention are useful in the treatment of conditions associated with such adhesion, including, but not limited to, such conditions as inflammatory and autoimmune responses, diabetes, asthma, psoriasis, inflammatory bowel disease, transplantation rejection, and tumor metastasis. Also disclosed are methods of inhibiting VLA-4 mediated cell adhesion and methods of treating conditions associated with LA-4 mediated cell adhesion.

Abstract: Finishing a seal assembly as a unit is proposed, which prevents alignment of the end gaps of the annular body and the annular ring of the seal assembly, provides the ability to manufacture the seal assembly to very low tolerances, and establishes virtually perfect parallelism between the upper and lower surfaces of the seal assembly. A finishing process is characterized by lapping a seal assembly as an assembled unit with a lapper using gritted oil as a polishing medium.

Abstract: N-heterocyclic compounds that block cytokine production via inhibition of p38 kinase are disclosed. In one embodiment, compounds of the present invention are represented by Formula I: Methods of production, pharmaceutical compositions and methods of treating conditions associated with inappropriate p38 kinase activity or TNF-? expression utilizing compounds of the present invention are also disclosed.

Abstract: A rotary crop processing unit for a combine is shown having a generally cylindrical rotor within a frusto-conical housing. The rotor is arranged in the housing with a generally constant gap between the rotor and the bottom of the housing along the housing length and with an increasing gap between the rotor and the top of the housing in the crop flow direction.

Abstract: Compounds that selectively inhibit the binding of ligands to &agr;4&bgr;1 integrin (VLA-4) and methods for their preparation are disclosed.

Abstract: This invention is directed to physiologically active compounds of formula (I) wherein represents a bicyclic ring system, of about 10 to about 13 ring members, in which the ring is an azaheterocycle, and the ring represents an azaheteroaryl ring, or an optionally halo substituted benzene ring; R1 represents hydrogen or a straight- or branched-chain alkyl group of 1 to about 4 carbon atoms, optionally substituted by hydroxy or one or more halogen atoms, or when Z1 represents a direct bond R1 may also represent a lower alkenyl or lower alkynyl group, or a formyl group; R2 represents hydrogen, alkenyl, alkoxy, alkyl, alkylsulphinyl, alkylsulphonyl, alkylthio, aryl, arylalkyloxy, arylalkylsulphinyl, arylalkylsulphonyl, arylalkylthio, aryloxy, arylsulphinyl, arylsulphonyl, arylthio, cyano, cycloalkenyl, cycloalkenyloxy, cycloalkyl, cycloalkyloxy, heteroaryl, heteroarylalkyloxy, heteroaryloxy, hydroxy, —SO2NR4R5, —NR4SO2R5, —

Abstract: Compounds that selectively inhibit the binding of ligands to &agr;4&bgr;1 integrin (VLA-4) and methods for their preparation are disclosed. In one embodiment, compounds of the invention are represented by Formula I: As selective inhibitors of VLA-4 mediated cell adhesion, compounds of the present invention are useful in the treatment of conditions associated with such adhesion, including, but not limited to, such conditions as inflammatory and autoimmune responses, diabetes, asthma, psoriasis, inflammatory bowel disease, transplantation rejection, and tumor metastasis. Also disclosed are pharmaceutical compositions, methods of inhibiting VLA-4 mediated cell adhesion and methods of treating conditions associated with LA-4 mediated cell adhesion, which involve compounds of Formula I.

Abstract: Compounds that selectively inhibit the binding of ligands to &agr;4&bgr;1 integrin (VLA-4) and methods for their preparation are disclosed.

Abstract: A rotary crop processing unit for a combine is shown having a generally cylindrical rotor within a frusto-conical housing. The rotor is arranged in the housing with a generally constant gap between the rotor and the bottom of the housing along the housing length and with an increasing gap between the rotor and the top of the housing in the crop flow direction.

Abstract: A rotary crop processing unit for a combine is having a generally cylindrical rotor within a frusto-conical housing. The rotor is arranged in the housing with a generally constant gap between the rotor and the bottom of the housing along the housing length and with an increasing gap between the rotor and the top of the housing in the crop flow direction.

Abstract: N-heterocyclic compounds that block cytokine production via inhibition of p38 kinase are disclosed.

Abstract: A rotary crop processing unit for a combine is shown having a generally cylindrical rotor within a frusto-conical housing. The rotor is arranged in the housing with a generally constant gap between the rotor and the bottom of the housing along the housing length and with an increasing gap between the rotor and the top of the housing in the crop flow direction.