Abstract: Equipment sets for the sequential administration of medical liquids wherein a primary liquid can be administered at a flow rate independent of the flow rate of a secondary liquid, and including a barrier substantially impervious to air to prevent the inadvertent administration of air when the secondary liquid is depleted. The equipment sets of this invention have a primary tube valve controlled by pilot liquid diverted from the secondary liquid flow path.

Abstract: Equipment sets for the sequential administration of medical liquids wherein a primary liquid can be administered at a flow rate independent of the flow rate of a secondary liquid, and including a barrier substantially impervious to air to prevent the inadvertent administration of air when the secondary liquid is depleted. The sets of this invention have a tube of reduced diameter to restrict the flow of primary liquid to a predetermined rate.

Abstract: Gravitational flow system and equipment sets for the sequential administration of medical liquids wherein a primary liquid can be administered at a flow rate independent of the flow rate of a secondary liquid, and including a barrier substantially impervious to air to prevent the inadvertent administration of air when the secondary liquid is depleted.

Abstract: Equipment sets for the sequential administration of medical liquids wherein a primary liquid can be administered at a flow rate independent of the flow rate of a secondary liquid, and including a barrier substantially impervious to air to prevent the inadvertent administration of air when the secondary liquid is depleted. The sets of this invention employ a novel flexible diaphragm valve as the air barrier.

Abstract: A pressure activated shut-off device which will prevent the flow of liquid in an intravenous administration set when the pressure in the system reaches a predetermined point. The shut-off device is utilized in an I.V. set wherein a pumping mechanism is utilized as the force for moving the liquid through a filter. The shut-off device has a biasing element which is set with a predetermined force so as to become activated and stop fluid flow so that the filter mechanism is not ruptured by excessive fluid pressure.

Abstract: Equipment sets for the sequential administration of medical liquids wherein a primary liquid can be administered at a flow rate independent of the flow rate of a secondary liquid, and including a barrier substantially impervious to air to prevent the inadvertent administration of air when the secondary liquid is depleted. The sets of this invention provide parallel flow paths for the secondary liquid to insure that the flow of primary liquid is interrupted while the secondary liquid is flowing. A 3-way valve is provided in the first parallel branch to facilitate priming of the set.

Abstract: Equipment sets for the sequential administration of medical liquids wherein a primary liquid can be administered at a flow rate independent of the flow rate of a secondary liquid, and including a barrier substantially impervious to air to prevent the inadvertent administration of air when the secondary liquid is depleted. The sets of this invention employ a combined air barrier and liquid sequencing valve controlled by a common flexible membrane.

Abstract: Gravitational flow system and equipment sets for the sequential administration of medical liquids wherein a primary liquid can be administered at a flow rate independent of the flow rate of a secondary liquid, and including a barrier substantially impervious to air to prevent the inadvertent administration of air when the secondary liquid is depleted. The sets of this invention provide parallel flow paths for the secondary liquid to insure that the flow of primary liquid is interrupted while the secondary liquid is flowing.

Abstract: A prefilled, readily activated syringe assembly wherein a fluid medicament and a diluent therefor can be intermixed in a syringe barrel with a venting thereof. A medical powder is sealed in a barrel by means of an intermediate slidable stopper and the diluent is sealed in the same barrel between the stopper and a plunger stopper. A bypass channel is provided in the syringe barrel which permits intermixing of the diluent and the medicament when the plunger stopper is moved toward the intermediate stopper. Movement of the plunger stopper inwardly in the barrel is afforded by means of a hydrophobic filter element associated with the nozzle portion. After intermixing of the diluent and the medicament the filter vent is pierced by means of a piercing tubular member to which is attached a hypodermic needle. Continued movement of the plunger stopper will expel the mixed medicament from the syringe.

Abstract: Equipment sets for the sequential administration of medical liquids wherein a primary liquid can be administered at a flow rate independent of the flow rate of a secondary liquid and prevent the inadvertent administration of air when the secondary liquid is depleted. The sets of this invention employ parallel flowpaths for the secondary liquid and a single liquid sequencing valve to control the flow of the primary liquid and the secondary liquid in one of the parallel flowpaths.

Abstract: An additive transfer device for storing and transferring of a medicament to a solution container such as an I.V. bag having an exposed port. The transfer device is accommodated in the neck of an additive container having a pierceable sealing element. A piercing guide member has a projecting tubular portion which extends into the tubular neck and affords a guide passageway for a piercing member with interlocking means being disposed in conjunction with the piercing guide member and the piercing member whereupon after their interlocking, the sealing element in the neck of the additive container is pierced. Wall means are provided from either the piercing guide member or the piercing member and fits over the tubular port of the I.V. bag. In the preferred embodiment, a needle guard member is utilized to actuate the interlocking means and afford the piercing of the pierceable sealing element. When the opposing pointed end of the piercing element is pierced through the I.V.

Abstract: A needle-inside, catheter placement assembly including a spliced, two-part needle and a catheter unit comprising a catheter, winged catheter insertion means, flexible tubing and tube hub, wherein axial and rotational alignment of the needle and catheter unit are maintained by mechanically interlocked complementary portions of the needle and lumen of the winged catheter insertion means.

Abstract: A preloaded, readily activated, disposable syringe wherein a first fluid diluent is sealed in a vial and is adapted to be received by a holding means in a syringe barrel. A second vial containing a fluid medicament is adapted to be engaged by a second holding means in the form of an adapter which is movable over the outside of the syringe barrel. A double-pointed cannula is positioned in the syringe barrel and has a hub with two frictional stop portions in conjunction with the syringe barrel. Upon movement of the adapter in the direction of the syringe barrel, one end of the cannula will pierce through the stopper secured to the adapter. Upon further movement of the adapter, it will contact the cannula hub and move it from a first retentive position to a second to thereby pierce the second stopper and provide fluid communication between the two vials. After mixing, the vial secured to the adapter will be emptied by moving it in a direction toward the syringe.

Abstract: A prefilled, ready to use, disposable syringe wherein a fluid medicament and a diluent therefor are sealed in two separate telescoping syringe barrels. A medicinal powder is sealed in an outer barrel adjacent the nozzle section by means of a pierceable stopper and the diluent is sealed in an inner barrel between another pierceable stopper and a plunger stopper. A double-pointed cannula is positioned between the two pierceable stoppers by means of a telescoping guide arrangement. Movement of the plunger stopper inwardly in the inner barrel initially effects a piercing of both pierceable stoppers and intermixing of the medicinal powder with the diluent. Continued movement of the plunger stopper will expel the mixed medicament from the syringe.

Abstract: An additive transfer device for storing and transferring of a medicament to a solution container such as an I.V. bag having an exposed port. The transfer device includes a vial-type container having a slidable pierceable sealing element. A holder member secures a piercing cannular member and the holder has a guide means at one end to fit around th exposed port of the I.V. bag. A cover extends over the guide means and is in sealing contact with the vial. Activating means are provided in conjunction with the cover, the holder and the vial to effect movement of the holder member toward the vial and piercing of the vial stopper by one end of the cannula. With a piercing of the I.V. port by means of the other pointed end of the cannula, communication can be made between the additive container and the I.V. bag.

Abstract: An additive transfer device for storing and transferring of a medicament to a solution container such as an I.V. bag having an exposed port. The transfer device is accommodated in the neck of an additive container having a pierceable sealing element. A holder member for a doubled pointed end piercing member engages a cap covering the tubular neck and affords a movement of the piercing member toward the sealing element to pierce it. Guide means extend from the holder member and fit over the tubular port of the I.V. bag. When the opposing pointed end of the piercing element is pierced through the I.V. port, communication can be made between the additive container and the I.V. bag. In a preferred manner, the contents of the additive container are expelled by collapsing the walls which force the medicament into the I.V. bag by means of the piercing element.