Abstract: A system and apparatus for performing transforaminal therapy utilizes a cannula positioned in the foramen ovale and a probe that is operable through an actuator to access the brain via the cannula. According to one aspect, the actuator can be a manual mechanical actuator. According to another aspect, the actuator can be a robotic actuator. According to a further aspect, the actuator can be adapted for use in an imaging environment, such as a magnetic resonance imaging (MRI) system.