Abstract: Aspirin (2-Acetoxybenzoic Acid) and Benadryl (diphenhydramine HCL) are widely known medications used for different medical problems. Each of these medications has been studied extensively however, a review did not identify any histologic investigation into combining the two entities together for any intended use such as for the management of |Benadryl-induced CNS-related adverse effects specifically, poor sleep quality, lingering drowsiness or difficulty concentrating, especially when enough sleep (about 7 hours) was not obtained. In these situations, patients often try several agents and practices to counteract Benadryl-induced aftereffects often with limited success.

Abstract: Provided is a method for depleting host nucleic acid in a biological sample, said sample having been previously obtained from an animal host, said method comprising the steps of (a) adding a cytolysin, or an active variant thereof, to said sample; and (b) carrying-out a process to physically deplete nucleic acid released from host cells within said sample or otherwise render such nucleic acid unidentifiable.

Abstract: Systems for performing methods which include receiving by a VPN server, from a VPN client operating on a computing device, over a VPN connection a first message including a first IP address. The VPN server determines a hostname based on the first IP address, resolves the hostname to a second IP address, and transmits the first message to a network device at the second IP address.

Abstract: A modular bidet attachment. The modular bidet attachment includes mounting discs that mount to a bidet chassis via a snap fit mechanism. The mounting discs include openings that are less than half the length of the diameter of the mounting discs. The mounting discs are configured to rotate after being mounted to the chassis.

Abstract: A sole for a shoe that includes a bottom sole platform for supporting a foot of a human. The bottom sole platform includes a top surface shaped to support the foot and a bottom surface spaced from and facing away from the top surface, wherein the bottom surface includes: a longitudinal axis intersecting a front end and a rear end of the bottom surface; and a lateral axis intersecting a curved instep portion of the bottom surface and perpendicular to the longitudinal axis. First, second, third, and fourth symmetric protrusions contacting the bottom surface including centers positioned to a right side of the longitudinal axis and forward or rear of the lateral axis and to a left side of the longitudinal axis and forward or rear of the lateral axis.

Abstract: Automated spatial feature engineering techniques may include (1) automatically deriving new features (e.g., spatial lags) based on spatial relationships between or among observations, (2) using parameter optimization techniques to optimize parameters of the spatial feature engineering process (e.g., parameters relating to the size of spatial neighborhoods and/or to the orders of spatial lags), (3) automatically deriving new spatial features representing geometric properties and/or spatial statistics associated with individual spatial observations, (4) determining the feature importance of location features, and/or (5) automatically partitioning spatial datasets such that spatial leakage is reduced, which generally leads to the development of more accurate spatial models. Such techniques may involve joint treatment of distinct location coordinate features as a single location feature for purposes of determining feature importance.

Abstract: An electrical steel strip that is less than 3 mm in thickness and is made from a molten electrical steel melt having a superheat temperature of at least 30° C. above the liquidus temperature Tliquidus of the melt comprising: by weight, up to 0.015% carbon, between 1.0% and 2.0% manganese, between 2.70% and 3.80% silicon, silicon killed containing less than 0.01% aluminum, and optionally any one or more of up Cu, Cr, Ni, Mo, Ti, Nb, V, Sb, and Sn; and the remainder iron, impurities and inclusions, is disclosed. A twin roll cast and hot rolled electrical steel strip is disclosed. A subsequently cold rolled and annealed electrical steel strip is also disclosed. Methods of producing these products via a twin roll strip caster are also disclosed.

Abstract: A battery pack assembly includes a header base of a header assembly. The header base is connectable to a battery pack enclosure. The header assembly further includes a grounding link that is contained within the header base. The grounding link establishes a ground path between the battery pack enclosure and one or more vehicle connectors that are coupled to the header assembly.

Abstract: An inductor is disclosed, including a first wire, a non-conductive material, and a shell. The non-conductive material may cover the first wire, with a portion of each end of the first wire uncovered. The shell may include a top portion and a bottom portion and include at least one magnetized layer and at least one gap between the first portion and the second portion. The shell may also surround a portion of the non-conductive material.

Abstract: The present invention relates to prostate cancer (PC), in particular the identification of certain bacteria in prostate cancer tissues or liquid biopsies and the use of such identification as a prognostic indicator of cancer progression. The present invention also relates to cultures of newly identified bacteria and means for identifying such bacteria in biological samples.

Abstract: The present application provides stable peptide-based Akt capture agents and methods of use as detection and diagnosis agents and in the treatment of diseases and disorders. The application further provides methods of manufacturing Akt capture agents using iterative on-bead in situ click chemistry.

Abstract: The present invention provides a method for depleting host nucleic acid in a biological sample, said sample having been previously obtained from an animal host and having been subjected to treatment to lyse host cells present in the sample, and optionally having been subjected to a treatment to deplete nucleic acid released from host cells within said sample or otherwise to render such nucleic acid unidentifiable, the method comprising: (a) depleting host mitochondria or host mitochondrial NA (mtDNA and/or mtRNA) present in the treated sample; and (b) extracting and/or analysing remaining nucleic acid from the treated sample. Also provided is a related kit comprising reagents for performing the method.

Abstract: Presented herein are techniques associated with replicating an OpenRoaming™ policy federation in a Third Generation Partnership Project (3GPP) network environment. For example, techniques herein provide a roaming policy federation architecture for a 3GPP network environment.

Abstract: A method of dicing a wafer includes positioning the wafer with its top side on a tape material. The wafer includes a plurality of die separated by scribe streets. A first pass being a first infrared (IR) laser beam is directed at the bottom side with a point of entry within the scribe streets. The first IR laser beam is focused with a focus point embedded within a thickness of the wafer, and has parameters selected to form an embedded crack line within the wafer. The embedded crack line does not reach the top side surface. A second pass being a second IR laser beam is directed at the bottom side having parameters selected to form a second crack line that that has a spacing relative to the embedded crack line, and the second IR laser beam causes the embedded crack line to be extended to the top side surface.

Abstract: Systems and methods for improved radiation treatment planning can employ hierarchical constrained optimization with relaxed constraints also referred to herein after as expedited hierarchical constrained optimization (ECHO). The systems and methods described herein employ a combination of constrained optimization and a correction loop involving unconstrained optimization to enhance the speed and efficiency of the radiation treatment planning process and improve the accuracy and quality of resulting radiation treatment plans. The use of a hierarchical constrained optimization approach leads to less complex and faster to solve optimization problems. The correction loop allows for compensating for optimization error associated with the sequence of constrained optimizations by incorporating such error in an unconstrained optimization. Hard and soft dose volume constraints can be efficiently incorporated.

Abstract: The present invention provides a method for depleting host nucleic acid in a biological sample, said sample having been previously obtained from an animal host and having been subjected to treatment to lyse host cells present in the sample, and having been subjected to a treatment to deplete nucleic acid released from host cells within said sample or otherwise to render such nucleic acid unidentifiable, the method comprising: (a) depleting host mitochondria or host mitochondrial DNA (mtDNA) present in the treated sample; and (b) extracting and/or analysing remaining nucleic acid from the treated sample. Also provided is a related kit comprising reagents for performing the method. Further claimed is a method for isolating mitochondrial DNA after host cells have been lysed and host cell nucleic acids have been removed from the sample.

Abstract: A computer-program product, computer-implemented method, and computer-implemented system includes obtaining a raw dataset; executing an outlier filtration process based on obtaining the raw dataset; training a model using a refined outlier-reduced dataset; and predicting, via the trained model, a value of the target entity at a future time.

Abstract: In examples, a method for manufacturing a semiconductor die comprises, prior to forming circuitry on a semiconductor wafer, forming a horizontal array of cracks in an interior of the wafer using a laser. The method also includes, after forming the horizontal array of cracks, forming circuitry on a device side of the wafer. The method includes forming conductive bumps on the device side of the wafer.

Abstract: The embodiments presented within provide methods, devices, and computer readable medium involving generation of power within a device, using this power to activate the device, measuring a physical characteristic of the power indicative of an external event, and then waking the device fully based on the external event. The device remains in a low-power sleep state until being woken based on the external event.