Patents by Inventor Joseph O. Falkinham

Joseph O. Falkinham has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9879048
    Abstract: In one aspect, the invention relates to isolated compounds useful as antifungal agents, for example, compounds having a structure represented by a formula: wherein R1 is hydrogen or hydroxyl; wherein R2 is hydrogen, a-xylose or ?-xylose; and wherein R3 and R4 are each hydrogen or together oxygen, or a pharmaceutically acceptable salt thereof; methods of isolating and purifying same; pharmaceutical compositions comprising same; agricultural compositions comprising same; and methods of treating and/or preventing fungal infections using same. In one aspect, R2 is not hydrogen or ?-xylose when R1 is hydroxyl and R3 and R4 are together oxygen. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Grant
    Filed: December 20, 2012
    Date of Patent: January 30, 2018
    Assignee: University of Utah Research Foundation
    Inventors: Eric W. Schmidt, Joseph O. Falkinham, Peter W. Jeffs
  • Patent number: 9139616
    Abstract: In one aspect, the invention relates to isolated compounds useful as antifungal agents, for example, compounds having a structure represented by a formula: wherein R1 is hydrogen or hydroxyl; wherein R2 is hydrogen or xylose; and wherein R3 and R4 are each hydrogen or together oxygen, or a pharmaceutically acceptable salt thereof; methods of isolating and purifying same; pharmaceutical compositions comprising same; agricultural compositions comprising same; and methods of treating and/or preventing fungal infections using same. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Grant
    Filed: July 17, 2014
    Date of Patent: September 22, 2015
    Assignee: University of Utah Research Foundation
    Inventors: Eric W. Schmidt, Joseph O. Falkinham, Peter W. Jeffs
  • Publication number: 20150024998
    Abstract: In one aspect, the invention relates to isolated compounds useful as antifungal agents, for example, compounds having a structure represented by a formula: wherein R1 is hydrogen or hydroxyl; wherein R2 is hydrogen, a-xylose or ?-xylose; and wherein R3 and R4 are each hydrogen or together oxygen, or a pharmaceutically acceptable salt thereof; methods of isolating and purifying same; pharmaceutical compositions comprising same; agricultural compositions comprising same; and methods of treating and/or preventing fungal infections using same. In one aspect, R2 is not hydrogen or ?-xylose when R1 is hydroxyl and R3 and R4 are together oxygen. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: December 20, 2012
    Publication date: January 22, 2015
    Applicant: UNIVERSITY OF UTAH RESEARCH FOUNDATION
    Inventors: Eric W. Schmidt, Joseph O. Falkinham, Peter W. Jeffs
  • Publication number: 20150018270
    Abstract: In one aspect, the invention relates to isolated compounds useful as antifungal agents, for example, compounds having a structure represented by a formula: wherein R1 is hydrogen or hydroxyl; wherein R2 is hydrogen or xylose; and wherein R3 and R4 are each hydrogen or together oxygen, or a pharmaceutically acceptable salt thereof; methods of isolating and purifying same; pharmaceutical compositions comprising same; agricultural compositions comprising same; and methods of treating and/or preventing fungal infections using same. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: July 17, 2014
    Publication date: January 15, 2015
    Inventors: Eric W. Schmidt, Joseph O. Falkinham, Peter W. Jeffs
  • Patent number: 8785376
    Abstract: In one aspect, the invention relates to isolated compounds useful as antifungal agents, for example, compounds having a structure represented by a formula: wherein R1 is hydrogen or hydroxyl; wherein R2 is hydrogen or xylose; and wherein R3 and R4 are each hydrogen or together oxygen, or a pharmaceutically acceptable salt thereof; methods of isolating and purifying same; pharmaceutical compositions comprising same; agricultural compositions comprising same; and methods of treating and/or preventing fungal infections using same. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Grant
    Filed: December 20, 2011
    Date of Patent: July 22, 2014
    Assignees: Virginia Tech Intellectual Properties, University of Utah Research Foundation
    Inventors: Eric W. Schmidt, Joseph O. Falkinham, Peter W. Jeffs
  • Publication number: 20130090284
    Abstract: In one aspect, the invention relates to isolated compounds useful as antifungal agents, for example, compounds having a structure represented by a formula: wherein R1 is hydrogen or hydroxyl; wherein R2 is hydrogen or xylose; and wherein R3 and R4 are each hydrogen or together oxygen, or a pharmaceutically acceptable salt thereof; methods of isolating and purifying same; pharmaceutical compositions comprising same; agricultural compositions comprising same; and methods of treating and/or preventing fungal infections using same. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: December 20, 2011
    Publication date: April 11, 2013
    Inventors: Eric W. Schmidt, Joseph O. Falkinham, Peter W. Jeffs
  • Patent number: 5527667
    Abstract: Viral contamination in water samples is detected using a medium which includes both a substrate for .beta.-galactosidase and E. coli with elevated levels of intracellular .beta.-galactosidase. The substrate is chosen to undergo a detectable change (e.g., colorimetric, fluorometric, photometric, etc.) upon cleavage by .beta.-galactosidase. A water sample to be tested for viral contamination is added to the medium. If coliphages are present in the water sample, they will infect, multiply within, and subsequently lyse the E. coli host. Lysis of the E. coli will allow the release of the intracellular .beta.-galactosidase into the media, whereupon the enzyme will cleave the substrate for a detectable reaction. In one particular application, a colorimetric reagent that serves as a substrate for .beta.-galactosidase is dissolved or dispersed within an agar medium, and in another particular application, a colorimetric reagent that serves as a substrate for .beta.
    Type: Grant
    Filed: May 25, 1993
    Date of Patent: June 18, 1996
    Assignees: Virginia Polytechnic Institute and State University, Virginia Tech Intellectual Properties, Inc., The Center for Innovative Technology
    Inventors: M. Marian Ijzerman, Charles Hagedorn, Joseph O. Falkinham