Abstract: Systems and methods facilitate sensing and tallying defecation events of subjects, such as participants in clinical trials for treatments for treating digestive diseases, such as irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and chronic constipation. Systems and methods may also be used by individual patients for sensing and tallying defecation events, and resulting data may be reviewed by a healthcare provider when evaluating patient gastrointestinal health and/or treatments.

Abstract: A method includes receiving, with a processor in communication with a first exercise machine, a first request for an exercise class, the first request being provided by a first user of the first exercise machine. The method also includes providing a video file associated with the exercise class to the first exercise machine, providing a notification to a second user indicating that the first user has chosen to participate in the exercise class, and receiving a second request for the exercise class provided by the second user. The method further includes providing the video file to a second exercise machine of the second user via the network. In such a method, display of the video file via a display of the second exercise machine is synchronized with display of the video file via a display of the first exercise machine.

Abstract: A method and system for removing a slurry from a surface impoundment to create a dewatered particulate cake on a filter bed is disclosed.

Abstract: Systems and methods for testing, evaluating, and scoring IT products (e.g., software) and product updates from a technology provider are disclosed herein. More specifically, organizational assessment may be performed to evaluate the provider's development lifecycle processes and generate organization maturity scores. Architecture assessment may be performed to evaluate the system-level and software-level architectures associated with the application and generate architecture maturity scores. Product verification may be performed via automated testing and penetration testing to generate verification maturity scores. The organization maturity scores, architecture maturity scores, and verification maturity scores may be used to provide recommendations to the provider and also combined into an overall maturity score, which may serve as a comprehensive summary of the evaluation. These generated scores inform and expedite testing of future iterations of the product.

Abstract: A humidification system can include a heater base, a chamber, and a breathing circuit. The heater base includes a heater plate positioned in a recessed region, and a heat conductive portion of the chamber is configured to contact the heater plate. The heater base includes a guard configured to control movement of the chamber into and out of the recessed region. The guard includes an anti-racking mechanism. The chamber includes an inlet port, an outlet port. A downward extension extends into the chamber from the inlet port, and a baffle is disposed at a lower end of the downward extension. A component of the breathing circuit can include a conduit hanging end cap for shipping and storage. The end cap can include a hanging component to allow the breathing circuit component to be hung from a medical stand. The system can detect when breathing circuits are connected in reverse.

Abstract: The invention relates to anti-VLA-4 antibodies and binding fragments thereof. The invention further includes polynucleotides encoding said antibodies and binding fragments thereof and methods of manufacturing said antibodies and binding fragments thereof. The invention further includes methods of treating patients suffering from multiple sclerosis and/or epilepsy by administration of said antibodies and binding fragments thereof. The invention further includes methods of reducing the susceptibility to scrambling of a recombinant anti-alpha 4 antibody or a binding fragment thereof.

Abstract: Described herein are systems and methods of processing immobilization molds for application of treatment, A computing system may generate a three-dimensional mold model of immobilization mold within with a subject is to be positioned for application of a treatment. The computing system may subtract a three-dimensional scan of at least a portion of the subject from the three-dimensional mold model to define an opening therein. The computing system may remove, from the three-dimensional mold model, a first portion to define an imprint in the opening from a first axis along which the subject is to enter. The computing system may remove, from a second portion of the three-dimensional mold model remaining with the removal of the first portion, inward protrusions into the imprint of relative to the second axis intersecting the first axis.

Abstract: Described herein are systems and methods of processing immobilization molds for application of treatment, A computing system may generate a three-dimensional mold model of immobilization mold within with a subject is to be positioned for application of a treatment. The computing system may subtract a three-dimensional scan of at least a portion of the subject from the three-dimensional mold model to define an opening therein. The computing system may remove, from the three-dimensional mold model, a first portion to define an imprint in the opening from a first axis along which the subject is to enter. The computing system may remove, from a second portion of the three-dimensional mold model remaining with the removal of the first portion, inward protrusions into the imprint of relative to the second axis intersecting the first axis.

Abstract: An apparatus for mooring a boat may include a mount body including a plurality of sidewalls forming a channel. A cleat may extend from a first of the plurality of sidewalls. A plate may be removably coupled to the mount body. The apparatus may include a clamping structure comprising a movable jaw coupled to a second of the plurality of sidewalls and configured to clamp the mount to a dock rail.

Abstract: A system and process for selecting, reserving, and purchasing mausoleum cemetery property and services via cloud application service is disclosed. The system and process for selecting, reserving, and purchasing mausoleum cemetery property and services via cloud application service provides an online e-commerce solution for selecting, reserving and purchasing mausoleum cemetery property and services.

Abstract: Described herein are systems and methods of processing immobilization molds for application of treatment, A computing system may generate a three-dimensional mold model of immobilization mold within with a subject is to be positioned for application of a treatment. The computing system may subtract a three-dimensional scan of at least a portion of the subject from the three-dimensional mold model to define an opening therein. The computing system may remove, from the three-dimensional mold model, a first portion to define an imprint in the opening from a first axis along which the subject is to enter. The computing system may remove, from a second portion of the three-dimensional mold model remaining with the removal of the first portion, inward protrusions into the imprint of relative to the second axis intersecting the first axis.

Abstract: Disclosed herein are methods, devices, and systems for manufacturing wind turbine blades which in some instances require using new blade joint designs. The blade joint designs described herein may allow for contact in places where welds will be made, which allows for existing manufacturing tolerances to be used while still enabling the use of thermal welding for wind turbine blades.

Abstract: An apparatus for mooring a boat may include a mount body including a plurality of sidewalls forming a channel. A cleat may extend from a first of the plurality of sidewalls. A plate may be removably coupled to the mount body. The apparatus may include a clamping structure comprising a movable jaw coupled to a second of the plurality of sidewalls and configured to clamp the mount to a dock rail.

Abstract: Described herein are systems and methods for synthetic CT image creation that allow MR-only radiotherapy of cancer patients, e.g., head and neck (H&N) cancer patients, prostate cancer patients, patients with cancer of the pelvis, abdomen cancer patients, patients with cancer of the extremities, brain cancer patients, or thorax cancer patients. The methods and systems described herein feature image processing techniques that improve the similarity between CT and MR images prior to CT-MR image registration, as well as standardization of the MR intensity histograms prior to MR-MR registration. Application of the techniques result in more accurate assignment of the Hounsfield unit to each point in the synthetic CT compared to other atlas-based methods, providing for more accurate dosing in MR-only radiotherapy simulation and planning.

Abstract: Described herein are systems and methods of processing immobilization molds for application of treatment, A computing system may generate a three-dimensional mold model of immobilization mold within with a subject is to be positioned for application of a treatment. The computing system may subtract a three-dimensional scan of at least a portion of the subject from the three-dimensional mold model to define an opening therein. The computing system may remove, from the three-dimensional mold model, a first portion to define an imprint in the opening from a first axis along which the subject is to enter. The computing system may remove, from a second portion of the three-dimensional mold model remaining with the removal of the first portion, inward protrusions into the imprint of relative to the second axis intersecting the first axis.

Abstract: A computer-implemented method includes generating a first list of products to recommend to a user. The following steps are then repeated: removing a first product from the first list and placing the first product in a second list wherein the order of the products in the second list determines the order that products appear on a user interface; and comparing each remaining product in the first list to the product placed on the second list and moving products that are similar to the product placed on the second list further down in the first list. A user interface is then generated from the second list to show suggested products to a user.

Abstract: The invention relates to methods of treating chronic intestinal inflammation and/or inflammatory bowel disease by administering an antagonist of oncostatin-M (OSM) and/or OSM receptor-? (OSMR). The invention also relates to methods for diagnosing or prognosing chronic intestinal inflammation and/or inflammatory bowel disease in an individual and for predicting whether or not an individual will respond to an anti-TNF? therapy. The methods comprise measuring OSM and/or OSMR in the individual.

Abstract: Disclosed herein are methods, devices, and systems for manufacturing wind turbine blades which in some instances require using new blade joint designs. The blade joint designs described herein may allow for contact in places where welds will be made, which allows for existing manufacturing tolerances to be used while still enabling the use of thermal welding for wind turbine blades.

Abstract: Described herein are systems and methods for synthetic CT image creation that allow MR-only radiotherapy of cancer patients, e.g., head and neck (H&N) cancer patients, prostate cancer patients, patients with cancer of the pelvis, abdomen cancer patients, patients with cancer of the extremities, brain cancer patients, or thorax cancer patients. The methods and systems described herein feature image processing techniques that improve the similarity between CT and MR images prior to CT-MR image registration, as well as standardization of the MR intensity histograms prior to MR-MR registration. Application of the techniques result in more accurate assignment of the Hounsfield unit to each point in the synthetic CT compared to other atlas-based methods, providing for more accurate dosing in MR-only radiotherapy simulation and planning.

Abstract: A system and related methods for securely processing financial transactions is described using a data communications network connecting a plurality of various types of nodes that transmit and receive encrypted data. User and vendor nodes are provided for purchasers and vendors to interact with the system. Communication nodes facilitate data transmission between the other nodes in the system.