Abstract: Human, swine and rat growth hormone secretagogue receptors have been isolated, cloned and sequenced. Growth hormone secretagogue receptors are new members of the G-protein family of receptors. The growth hormone secretagogue receptors may be used to screen and identify compounds which bind to the growth hormone secretagogue receptor. Such compounds may be used in the treatment of conditions which occur when there is a shortage of growth hormone, such as observed in growth hormone deficient children, elderly patients with musculoskeletal impairment and recovering from hip fracture and osteoporosis.

Abstract: Human, swine and rat growth hormone secretagogue receptors have been isolated, cloned and sequenced. Growth hormone secretagogue receptors are new members of the G-protein family of receptors. The growth hormone secretagogue receptors may be used to screen and identify compounds which bind to the growth hormone secretagogue receptor. Such compounds may be used in the treatment of conditions which occur when there is a shortage of growth hormone, such as observed in growth hormone deficient children, elderly patients with musculoskeletal impairment and recovering from hip fracture and osteoporosis.

Abstract: DNA encoding glutamate and avermectin-sensitive chloride channels have been cloned and characterized. The protein is capable of forming channels selectively opened with either avermectin or glutamate. The cDNA has been expressed in recombinant host cells which produce active recombinant protein. The recombinant protein is also purified from the recombinant host cells. In addition, the recombinant host cells are utilized to establish a method for identifying modulators of the receptor activity, and receptor modulators are identified. Receptor modulators active in the method disclosed herein are useful as ectoparasiticides, antiparasitic, anthelmenthic, acaracidal and insecticide agents.

Abstract: DNAs encoding voltage-activated cation channels have been cloned and characterized. The cDNA's have been expressed in recombinant host cells which produce active recombinant protein. The recombinant protein is also purified from the recombinant host cells.

Abstract: DNAs encoding voltage-activated cation channels have been cloned and characterized. The cDNA's have been expressed in recombinant host cells which produce active recombinant protein. The recombinant protein is also purified from the recombinant host cells.

Abstract: DNAs encoding glutamate and avermectin-sensitive chloride channels have been cloned and characterized. The individual alpha and beta subunits are capable of forming homomeric and heteromeric channels selectively opened with either avermectin or glutamate. The cDNA's have been expressed in recombinant host cells which produce active recombinant protein. The recombinant protein is also purified from the recombinant host cells. In addition, the recombinant host cells are utilized to establish a method for identifying modulators of the receptor activity, and receptor modulators are identified. Receptor modulators are useful as insecticides and anthelminthic agents.

Abstract: Vertical blinds having commonly housed and traversely movable controls for controlling the traverse and rotation of the vanes are disclosed. In a disclosed embodiment, the vanes are supported by carrier members, and a rotation rod extends through the carrier members. The carrier members are slideable along the rotation rod. A control assembly is mounted to slide along and also rotate the rotation rod. Sliding of the control assembly along the rotation rod slides the carrier members to thereby traverse the vanes, and actuation of the control assembly rotates the rotation rod and the vanes. The control assembly includes meshing bevel gears, one of which is coupled to an actuating rod or wand and the other to the rotation rod whereby rotation of the wand causes rotation of the vanes. The control assembly is slid by means of the wand which is universally connected to the control assembly. The wand is thus a unitary control for actuating both traverse and rotation of the vanes.

Abstract: A support member for horizontal members or elements in a traversable opening covering device is disclosed. In the preferred embodiment, the opening covering device is a vertical blind for a window opening. The vertical blind includes a plurality of vanes and carriers supporting the vanes, and a track structure for traversably supporting the carriers. The rod controls movement of the vanes, i.e. traversing or rotating of the vanes. In the preferred embodiment, the carriers are traversed by a cord arrangement and the support member also supports the cord.

Abstract: A unitary, one-piece vane carrier for vertical blinds is disclosed. The unitary carrier includes a carrier body and an elongated spacer link extending from one end of the body, the spacer link and body forming a single, unitary piece. In a disclosed embodiment, a tab is disposed at the distal end of the spacer link and a slotted opening is located in the end of the carrier body opposed to the end from which the spacer link extends. In that embodiment, the tab of one carrier cooperates with the slotted opening of an adjacently positioned carrier to limit the maximum spacing between the two carriers. The spacer link extends from the top of one end of the carrier body while the slotted opening is oppositely located at the top of the other end such that the spacer link of one carrier is slidable through the slotted opening of the adjacent carrier.