Patents by Inventor Joseph P. Giuffrida

Joseph P. Giuffrida has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11040198
    Abstract: The present invention relates to methods for remotely tuning treatment parameters in movement disorder therapy systems where the subject and clinician are located remotely from each other. The present invention still further provides methods of quantifying movement disorders for the treatment of patients who exhibit symptoms of such movement disorders including, but not limited to, Parkinson's disease and Parkinsonism, Dystonia, Chorea, and Huntington's disease, Ataxia, Tremor and Essential Tremor, Tourette syndrome, stroke, and the like. The present invention yet further relates to methods of remotely tuning a therapy device using objective quantified movement disorder symptom data to determine the therapy setting or parameters to be transmitted and provided to the subject via his or her therapy device. The present invention also provides treatment and tuning remotely, allowing for home monitoring of subjects.
    Type: Grant
    Filed: February 5, 2016
    Date of Patent: June 22, 2021
    Assignee: Great Lakes NeuroTechnologies Inc.
    Inventors: Joseph P Giuffrida, Dustin A Heldman, Thomas O Mera
  • Patent number: 11040203
    Abstract: The present invention relates to methods for remotely tuning treatment parameters in movement disorder therapy systems where the subject and clinician are located remotely from each other. The present invention still further provides methods of quantifying movement disorders for the treatment of patients who exhibit symptoms of such movement disorders including, but not limited to, Parkinson's disease and Parkinsonism, Dystonia, Chorea, and Huntington's disease, Ataxia, Tremor and Essential Tremor, Tourette syndrome, stroke, and the like. The present invention yet further relates to methods of remotely tuning a therapy device using objective quantified movement disorder symptom data to determine the therapy setting or parameters to be transmitted and provided to the subject via his or her therapy device. The present invention also provides treatment and tuning remotely, allowing for home monitoring of subjects.
    Type: Grant
    Filed: February 5, 2016
    Date of Patent: June 22, 2021
    Assignee: Great Lakes NeuroTechnologies Inc.
    Inventors: Joseph P Giuffrida, Dustin A Heldman, Thomas O Mera
  • Patent number: 10994132
    Abstract: The present invention relates to a system and methods for noninvasively providing therapy for movement disorder symptoms. The present invention provides such a therapy system which provides trans-cranial direct current stimulation (tDCS) in order to treat those symptoms and the disorders. The present invention further provides such tDCS therapy while the subject sleeps in order to minimize the time required and impact of the therapy on the subject's waking life. The system, methods, and devices of the present invention are intended to provide a low-dose electrical current, trans-cranially, to a specific area of the subject's brain while he or she sleeps in order to decrease the occurrence, severity, and duration of the symptoms of movement disorders. The present invention aims to reduce the amount of medication necessary, counteract the effects of medication wearing off during sleep, and to overall improve the quality of life of subjects suffering from movement disorders.
    Type: Grant
    Filed: April 4, 2019
    Date of Patent: May 4, 2021
    Assignee: Great Lakes NeuroTechnologies Inc.
    Inventors: Dustin A Heldman, Joseph P Giuffrida
  • Patent number: 10974049
    Abstract: The present invention relates to methods for remotely and intelligently tuning movement disorder of therapy systems. The present invention still further provides methods of quantifying movement disorders for the treatment of patients who exhibit symptoms of such movement disorders including, but not limited to, Parkinson's disease and Parkinsonism, Dystonia, Chorea, and Huntington's disease, Ataxia, Tremor and Essential Tremor, Tourette syndrome, stroke, and the like. The present invention yet further relates to methods of remotely and intelligently or automatically tuning a therapy device using objective quantified movement disorder symptom data to determine the therapy setting or parameters to be transmitted and provided to the subject via his or her therapy device. The present invention also provides treatment and tuning intelligently, automatically and remotely, allowing for home monitoring of subjects.
    Type: Grant
    Filed: May 31, 2018
    Date of Patent: April 13, 2021
    Assignee: Great Lakes NeuroTechnologies Inc
    Inventors: Dustin A Heldman, Christopher L Pulliam, Joseph P Giuffrida, Thomas O Mera
  • Patent number: 10966652
    Abstract: A system and method for scoring movement disorder symptoms comprises a movement measurement data acquisition system and processing comprising kinematic feature extraction and an algorithm trained using Unified Parkinson's Disease Rating Scale (UPDRS) and Movement Disorder Society UPDRS (MDS-UPDRS) scores from skilled clinicians. The movement data acquisition system, or “movement measuring apparatus,” may comprise sensors such as accelerometers or gyroscopes or may utilize motion capture and/or machine vision technology or various other methods to measure tremor, bradykinesia, gait and balance disturbances, dyskinesia, or other movement disorders in a subject afflicted with Parkinson's disease, essential tremor or the like. The method outputs, and system displays, a score that uses and inclusive 0-4 scale that correlates to the UPDRS and MDS-UPDRS, or to a particular component of the movement disorder such as speed, amplitude or rhythm, but has greater resolution and lower variability.
    Type: Grant
    Filed: June 3, 2011
    Date of Patent: April 6, 2021
    Assignee: Great Lakes NeuroTechnologies Inc.
    Inventors: Joseph P. Giuffrida, Dustin A. Heldman, Thomas O. Mera
  • Publication number: 20210085976
    Abstract: The present invention relates to methods for remotely and intelligently tuning movement disorder of therapy systems. The present invention still further provides methods of quantifying movement disorders for the treatment of patients who exhibit symptoms of such movement disorders including, but not limited to, Parkinson's disease and Parkinsonism, Dystonia, Chorea, and Huntington's disease, Ataxia, Tremor and Essential Tremor, Tourette syndrome, stroke, and the like. The present invention yet further relates to methods of remotely and intelligently or automatically tuning a therapy device using objective quantified movement disorder symptom data to determine the therapy setting or parameters to be transmitted and provided to the subject via his or her therapy device. The present invention also provides treatment and tuning intelligently, automatically and remotely, allowing for home monitoring of subjects.
    Type: Application
    Filed: October 13, 2020
    Publication date: March 25, 2021
    Applicant: Great Lakes NeuroTechnologies Inc.
    Inventors: Dustin A. Heldman, Christopher L. Pulliam, Joseph P. Giuffrida, Thomas O. Mera
  • Patent number: 10881856
    Abstract: The present invention relates to systems adapted for remotely and intelligently tuning movement disorder of therapy systems. The present invention still further provides systems adapted for quantifying movement disorders for the treatment of patients who exhibit symptoms of such movement disorders including, but not limited to, Parkinson's disease and Parkinsonism, Dystonia, Chorea, and Huntington's disease, Ataxia, Tremor and Essential Tremor, Tourette syndrome, stroke, and the like. The present invention yet further relates to systems adapted for remotely and intelligently or automatically tuning a therapy device using objective quantified movement disorder symptom data to determine the therapy setting or parameters to be transmitted and provided to the subject via his or her therapy device. The systems of the present invention also are adapted to provide treatment and tuning intelligently, automatically and remotely, allowing for home monitoring of subjects.
    Type: Grant
    Filed: August 22, 2018
    Date of Patent: January 5, 2021
    Assignee: Great Lakes NeuroTechnologies Inc.
    Inventors: Dustin A. Heldman, Christopher L. Pulliam, Joseph P. Giuffrida, Thomas O. Mera
  • Patent number: 10786625
    Abstract: The present invention relates to a movement disorder monitor with high sensitivity, and a method of measuring the severity of a subject's movement disorder. The present invention additionally relates to a drug delivery system for dosing a subject in response to the increased severity of a subject's symptoms. The present invention provides for a system and method, which can accurately and repeatably quantify symptoms of movements disorders, accurately quantifies symptoms utilizing both kinetic information and/or electromyography (EMG) data, that can be worn continuously to provide continuous information to be analyzed as needed by the clinician, that can provide analysis in real-time, that allows for home monitoring of symptoms in subject's with these movement disorders to capture the complex fluctuation patterns of the disease over the course of days, weeks or months, that maximizes subject safety, and that provides substantially real-time remote access to data by the clinician or physician.
    Type: Grant
    Filed: February 28, 2014
    Date of Patent: September 29, 2020
    Assignee: Great Lakes NeuroTechnologies Inc.
    Inventors: Joseph P Giuffrida, Dustin A Heldman
  • Patent number: 10786199
    Abstract: The present invention relates to a movement disorder monitor, and a method of measuring the severity of a subject's movement disorder. The present invention additionally relates to a treatment delivery system for treating a subject in response to changes in the severity of a subject's symptoms. The present invention further provides for a system and method, which can accurately quantify symptoms of movement disorders, utilizing continuously obtained kinetic information to be analyzed, accurately distinguishing between symptoms of movement disorders and activities of daily living, relating quantified symptoms to a standard clinical rating scale, and correlating a subject's symptoms with certain physiological and environmental factors. The present invention still further provides for home monitoring of symptoms in subjects with these movement disorders in order to capture the complex fluctuation patterns of the disease over the course of days, weeks, months, or years.
    Type: Grant
    Filed: December 20, 2017
    Date of Patent: September 29, 2020
    Assignee: Great Lakes NeuroTechnologies Inc.
    Inventors: Joseph P Giuffrida, Dustin A Heldman, Thomas O Mera
  • Patent number: 10694992
    Abstract: The present invention is directed to a device and method for monitoring and assessment of movement disorder symptoms. The device and method disclosed herein are particularly amenable to remote monitoring of a subject's movement disorder symptoms. Briefly stated, in certain preferred embodiments of the present invention the movement disorder monitoring device accompanies a subject to a remote location where the device is used to record data relating to the severity of a subject's movement disorder symptoms over a period of time. This data is then subsequently used by physicians or other clinicians in optimizing and assessing treatment options directed at alleviating a subject's movement disorder symptoms. The method and device of the present invention can be used to monitor symptoms of a number of movement disorders including but not limited to dystonia, essential tremor, Huntington's disease, various ataxias, multiple sclerosis, psychogenic tremor, and Parkinson's disease.
    Type: Grant
    Filed: August 22, 2018
    Date of Patent: June 30, 2020
    Assignee: Great Lakes NeuroTechnologies Inc.
    Inventors: Joseph P. Giuffrida, Dustin A. Heldman, Thomas O. Mera
  • Patent number: 10478626
    Abstract: The present invention relates to methods for tuning treatment parameters in movement disorder therapy systems. The present invention further relates to a system for screening patients to determine viability as candidates for certain therapy modalities, such as deep brain stimulation (DBS). The present invention still further provides methods of quantifying movement disorders for the treatment of patients who exhibit symptoms of such movement disorders including, but not limited to, Parkinson's disease and Parkinsonism, Dystonia, Chorea, and Huntington's disease, Ataxia, Tremor and Essential Tremor, Tourette syndrome, stroke, and the like. The present invention yet further relates to methods of tuning a therapy device using objective quantified movement disorder symptom data acquired by a movement disorder diagnostic device to determine the therapy setting or parameters to be provided to the subject via his or her therapy device.
    Type: Grant
    Filed: June 26, 2017
    Date of Patent: November 19, 2019
    Assignee: Great Lakes NeuroTechnologies Inc.
    Inventors: Dustin A Heldman, Christopher L Pulliam, Joseph P Giuffrida, Thomas O Mera
  • Patent number: 10383571
    Abstract: The present invention relates to systems, devices and methods for acquiring, measuring, monitoring, processing and analyzing physiological signals. More particularly, the present invention relates to using physiological signals to determine a subject's response to various conditions, variables or constraints. Still more particularly, the present invention relates to monitoring the subject's external body motion and/or environmental factors and determining the amount of pain a subject is suffering as a result of the motion and factors. Still more particularly, the present invention relates to a system, device and methods of quantifying a subject's pain to provide an objective measurement of the subject's pain. The present invention further relates to establishing and improving pain management protocols and therapy or treatment for the subject's pain based on the quantified pain measurement.
    Type: Grant
    Filed: September 8, 2017
    Date of Patent: August 20, 2019
    Assignee: Great Lakes NeuroTechnologies Inc.
    Inventors: Christopher L. Pulliam, Joseph P Giuffrida
  • Publication number: 20180361153
    Abstract: The present invention relates to methods for remotely and intelligently tuning movement disorder of therapy systems. The present invention still further provides methods of quantifying movement disorders for the treatment of patients who exhibit symptoms of such movement disorders including, but not limited to, Parkinson's disease and Parkinsonism, Dystonia, Chorea, and Huntington's disease, Ataxia, Tremor and Essential Tremor, Tourette syndrome, stroke, and the like. The present invention yet further relates to methods of remotely and intelligently or automatically tuning a therapy device using objective quantified movement disorder symptom data to determine the therapy setting or parameters to be transmitted and provided to the subject via his or her therapy device. The present invention also provides treatment and tuning intelligently, automatically and remotely, allowing for home monitoring of subjects.
    Type: Application
    Filed: August 22, 2018
    Publication date: December 20, 2018
    Applicant: Great Lakes NeuroTechnologies Inc.
    Inventors: Dustin A. Heldman, Christopher L. Pulliam, Joseph P. Giuffrida, Thomas O. Mera
  • Patent number: 10092754
    Abstract: The present invention relates to methods for remotely and intelligently tuning movement disorder of therapy systems. The present invention still further provides methods of quantifying movement disorders for the treatment of patients who exhibit symptoms of such movement disorders including, but not limited to, Parkinson's disease and Parkinsonism, Dystonia, Chorea, and Huntington's disease, Ataxia, Tremor and Essential Tremor, Tourette syndrome, stroke, and the like. The present invention yet further relates to methods of remotely and intelligently or automatically tuning a therapy device using objective quantified movement disorder symptom data to determine the therapy setting or parameters to be transmitted and provided to the subject via his or her therapy device. The present invention also provides treatment and tuning intelligently, automatically and remotely, allowing for home monitoring of subjects.
    Type: Grant
    Filed: September 29, 2016
    Date of Patent: October 9, 2018
    Assignee: Great Lakes NeuroTechnologies Inc.
    Inventors: Dustin A Heldman, Christopher L Pulliam, Joseph P Giuffrida, Thomas O Mera
  • Patent number: 10085689
    Abstract: The present invention is directed to a device and method for monitoring and assessment of movement disorder symptoms. The device and method disclosed herein are particularly amenable to remote monitoring of a subject's movement disorder symptoms. Briefly stated, in certain preferred embodiments of the present invention the movement disorder monitoring device accompanies a subject to a remote location where the device is used to record data relating to the severity of a subject's movement disorder symptoms over a period of time. This data is then subsequently used by physicians or other clinicians in optimizing and assessing treatment options directed at alleviating a subject's movement disorder symptoms. The method and device of the present invention can be used to monitor symptoms of a number of movement disorders including but not limited to dystonia, essential tremor, Huntington's disease, various ataxias, multiple sclerosis, psychogenic tremor, and Parkinson's disease.
    Type: Grant
    Filed: July 15, 2016
    Date of Patent: October 2, 2018
    Assignee: Great Lakes NeuroTechnolgies Inc.
    Inventors: Joseph P. Giuffrida, Dustin A. Heldman, Thomas O. Mera
  • Patent number: 9974478
    Abstract: The present invention relates to systems and methods for helping subjects improve safety and efficiency of their movements; particularly subjects who have suffered an injury or suffer from a movement or other such disorder. More particularly, the present invention relates to such a system and method for monitoring a subject's movement to detect or predict unsafe, undesirable, or impaired movements, or symptoms of movement disorders, and also a system for providing possible treatment methods for such conditions. The present invention further relates to a method and system of providing cues or stimuli to the subject when such unsafe or undesirable movements, instabilities or symptoms are detected or predicted. Most particularly, the present invention relates to a subject-customized and adaptive movement recovery system, and method of providing therapy and training to improve functional motor recovery and safety of movement of a subject suffering from an injury or from movement disorder(s).
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: May 22, 2018
    Assignee: Great Lakes NeuroTechnologies Inc.
    Inventors: Elizabeth Brokaw, Dustin A. Heldman, Christopher L. Pulliam, Joseph P. Giuffrida
  • Patent number: 9877680
    Abstract: The present invention relates to a movement disorder monitor, and a method of measuring the severity of a subject's movement disorder. The present invention additionally relates to a treatment delivery system for treating a subject in response to changes in the severity of a subject's symptoms. The present invention further provides for a system and method, which can accurately quantify symptoms of movement disorders, utilizing continuously obtained kinetic information to be analyzed, accurately distinguishing between symptoms of movement disorders and activities of daily living, relating quantified symptoms to a standard clinical rating scale, and correlating a subject's symptoms with certain physiological and environmental factors. The present invention still further provides for home monitoring of symptoms in subjects with these movement disorders in order to capture the complex fluctuation patterns of the disease over the course of days, weeks, months, or years.
    Type: Grant
    Filed: February 15, 2016
    Date of Patent: January 30, 2018
    Assignee: Great Lakes NeuroTechnologies Inc.
    Inventors: Joseph P Giuffrida, Dustin A Heldman, Thomas O Mera
  • Patent number: 9782122
    Abstract: The present invention relates to systems, devices and methods for acquiring, measuring, monitoring, processing and analyzing physiological signals. More particularly, the present invention relates to using physiological signals to determine a subject's response to various conditions, variables or constraints. Still more particularly, the present invention relates to monitoring the subject's external body motion and/or environmental factors and determining the amount of pain a subject is suffering as a result of the motion and factors. Still more particularly, the present invention relates to a system, device and methods of quantifying a subject's pain to provide an objective measurement of the subject's pain. The present invention further relates to establishing and improving pain management protocols and therapy or treatment for the subject's pain based on the quantified pain measurement.
    Type: Grant
    Filed: February 4, 2015
    Date of Patent: October 10, 2017
    Assignee: Great Lakes NeuroTechnologies Inc
    Inventors: Christopher L Pulliam, Joseph P Giuffrida
  • Patent number: 9717920
    Abstract: The present invention relates to methods for tuning treatment parameters in movement disorder therapy systems. The present invention further relates to a system for screening patients to determine viability as candidates for certain therapy modalities, such as deep brain stimulation (DBS). The present invention still further provides methods of quantifying movement disorders for the treatment of patients who exhibit symptoms of such movement disorders including, but not limited to, Parkinson's disease and Parkinsonism, Dystonia, Chorea, and Huntington's disease, Ataxia, Tremor and Essential Tremor, Tourette syndrome, stroke, and the like. The present invention yet further relates to methods of tuning a therapy device using objective quantified movement disorder symptom data acquired by a movement disorder diagnostic device to determine the therapy setting or parameters to be provided to the subject via his or her therapy device.
    Type: Grant
    Filed: November 5, 2015
    Date of Patent: August 1, 2017
    Assignee: Great Lakes NeuroTechnologies Inc.
    Inventors: Dustin A Heldman, Christopher L Pulliam, Joseph P Giuffrida, Thomas O Mera
  • Patent number: 9662502
    Abstract: A system and method for tuning the parameters of a therapeutic medical device comprises a movement measurement data acquisition system capable of wireless transmission; processing comprising kinematic feature extraction, a scoring algorithm trained using scores from expert clinicians, a therapeutic device parameter setting adjustment suggestion algorithm preferably trained using the parameter setting adjustment judgments of expert clinicians; and a display and/or means of updating the parameter settings of the treatment device. The invention facilitates the treatment of movement disorders including Parkinson's disease, essential tremor and the like by optimizing deep brain stimulation (DBS) parameter settings, eliminating as much as possible motor symptoms and reducing time and costs of surgical and outpatient procedures and improving patient outcomes.
    Type: Grant
    Filed: June 3, 2011
    Date of Patent: May 30, 2017
    Assignee: Great Lakes Neurotechnologies Inc.
    Inventors: Joseph P. Giuffrida, Dustin A. Heldman, Thomas O. Mera