Patents by Inventor Joseph P. Mathew

Joseph P. Mathew has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for identifying altered effectiveness of beta blocker therapy
    Patent number: 10378056
    Abstract: The present invention provides a method of identifying a human subject as having an increased risk of altered effectiveness of beta blocker therapy, comprising detecting in the subject one or more single nucleotide polymorphism associated with increased risk of altered effectiveness of beta blocker therapy.
    Type: Grant
    Filed: June 30, 2016
    Date of Patent: August 13, 2019
    Assignee: Duke University
    Inventors: Miklos D. Kertai, Mihai V. Podgoreanu, Joseph P. Mathew, Yi-Ju Li
  • COMPOSITIONS AND METHODS FOR TREATING POST OPERATIVE COGNITIVE DYSFUNCTION AND NEUROINFLAMMATION WITH ANNEXIN A1 (ANXA1) PEPTIDES
    Publication number: 20180153952
    Abstract: The present disclosure provides compositions and methods for treating post-operative cognitive dysfunction with Annexin A1 (ANXA1) peptides.
    Type: Application
    Filed: December 1, 2017
    Publication date: June 7, 2018
    Inventors: Zhiquan Zhang, Niccolo Terrando, Qing Ma, Mihai V. Podgoreanu, Joseph P. Mathew, Mark F. Newman
  • Methods of identifying individuals at risk of perioperative bleeding, renal dysfunction or stroke
    Patent number: 9556486
    Abstract: The present invention relates, in general, to perioperative bleeding and, in particular, to methods of identifying individuals at risk of perioperative bleeding. The present invention relates, in general, to perioperative renal dysfunction and, in particular, to methods of identifying individuals at risk of perioperative renal dysfunction. The present invention relates, in general, to perioperative stroke and, in particular, to methods of identifying individuals at risk of perioperative stroke.
    Type: Grant
    Filed: December 6, 2013
    Date of Patent: January 31, 2017
    Assignee: Duke University
    Inventors: Debra A. Schwinn, Ian Welsby, Mihai V. Podgoreanu, Mark Stafford-Smith, Mark F. Newman, Hilary P. Grocott, William D. White, Richard W. Morris, Joseph P. Mathew
  • COMPOSITIONS AND METHODS FOR IDENTIFYING ALTERED EFFECTIVENESS OF BETA BLOCKER THERAPY
    Publication number: 20170002417
    Abstract: The present invention provides a method of identifying a human subject as having an increased risk of altered effectiveness of beta blocker therapy, comprising detecting in the subject one or more single nucleotide polymorphism associated with increased risk of altered effectiveness of beta blocker therapy.
    Type: Application
    Filed: June 30, 2016
    Publication date: January 5, 2017
    Inventors: Miklos D. Kertai, Mihai V. Podgoreanu, Joseph P. Mathew, Yi-Ju Li
  • METHODS OF IDENTIFYING INDIVIDUALS AT RISK OF PERIOPERATIVE BLEEDING, RENAL DYSFUNCTION OR STROKE
    Publication number: 20140141429
    Abstract: The present invention relates, in general, to perioperative bleeding and, in particular, to methods of identifying individuals at risk of perioperative bleeding. The present invention relates, in general, to perioperative renal dysfunction and, in particular, to methods of identifying individuals at risk of perioperative renal dysfunction. The present invention relates, in general, to perioperative stroke and, in particular, to methods of identifying individuals at risk of perioperative stroke.
    Type: Application
    Filed: December 6, 2013
    Publication date: May 22, 2014
    Applicant: DUKE UNIVERSITY
    Inventors: Debra A. SCHWINN, Ian Welsby, Mihai V. Podgoreanu, Mark Stafford-Smith, Mark F. Newman, Hilary P. Grocott, William D. White, Richard W. Morris, Joseph P. Mathew
  • METHODS OF IDENTIFYING INDIVIDUALS AT RISK OF PERIOPERATIVE BLEEDING, RENAL DYSFUNCTION OR STROKE
    Publication number: 20120322667
    Abstract: The present invention relates, in general, to perioperative bleeding and, in particular, to methods of identifying individuals at risk of perioperative bleeding. The present invention relates, in general, to perioperative renal dysfunction and, in particular, to methods of identifying individuals at risk of perioperative renal dysfunction. The present invention relates, in general, to perioperative stroke and, in particular, to methods of identifying individuals at risk of perioperative stroke.
    Type: Application
    Filed: April 24, 2012
    Publication date: December 20, 2012
    Applicant: DUKE UNIVERSITY
    Inventors: Debra A. Schwinn, Ian Welsby, Mihai V. Podgoreanu, Mark Stafford-Smith, Mark F. Newman, Hilary P. Grocott, William D. White, Richard W. Morris, Joseph P. Mathew
  • Methods of identifying individuals at risk of perioperative bleeding, renal dysfunction or stroke
    Patent number: 8187807
    Abstract: The present invention relates, in general, to perioperative bleeding and, in particular, to methods of identifying individuals at risk of perioperative bleeding. The present invention relates, in general, to perioperative renal dysfunction and, in particular, to methods of identifying individuals at risk of perioperative renal dysfunction. The present invention relates, in general, to perioperative stroke and, in particular, to methods of identifying individuals at risk of perioperative stroke.
    Type: Grant
    Filed: February 29, 2008
    Date of Patent: May 29, 2012
    Assignee: Duke University
    Inventors: Debra A. Schwinn, Ian Welsby, Mihai V. Podgoreanu, Mark Stafford-Smith, Mark F. Newman, Hilary P. Grocott, William D. White, Richard W. Morris, Joseph P. Mathew
  • Predictors of long-term mortality following coronary artery bypass graft surgery
    Patent number: 8105781
    Abstract: The present invention relates, in general, to perioperative depression and, in particular, to methods of identifying individuals at risk of perioperative depression.
    Type: Grant
    Filed: October 14, 2008
    Date of Patent: January 31, 2012
    Assignee: Duke University
    Inventors: Mihal V. Podgoreanu, Joseph P. Mathew, Robert L. Lobato, Mark F. Newman, Mark Stafford-Smith, William D. White
  • Method of identifying individuals at risk of perioperative myocardial injury, major adverse cardiac events, cognitive decline, arrhythmias, depression or bleeding
    Publication number: 20100047775
    Abstract: The present invention relates to methods of identifying individuals at risk of perioperative myocardial injury, major adverse cardiac events, cognitive decline, arrhythmias, depression and bleeding.
    Type: Application
    Filed: April 24, 2006
    Publication date: February 25, 2010
    Inventors: Debra A Schwinn, Mihai V. Podgoreanu, Joseph P. Mathew, Hilary P. Grocott, William D. White, Richard W. Morris, Mark F. Newman, Barbara Phillips-Bute, Ian Welsby
  • PREDICTORS OF LONG-TERM MORTALITY FOLLOWING CORONARY ARTERY BYPASS GRAFT SURGERY
    Publication number: 20090155792
    Abstract: The present invention relates, in general, to perioperative depression and, in particular, to methods of identifying individuals at risk of perioperative depression.
    Type: Application
    Filed: October 14, 2008
    Publication date: June 18, 2009
    Inventors: Mihai V. Podgoreanu, Joseph P. Mathew, Robert L. Lobato, Mark F. Newman, Mark Stafford-Smith, William D. White
  • Methods of identifying individuals at risk of perioperative bleeding, renal dysfunction or stroke
    Publication number: 20090075271
    Abstract: The present invention relates, in general, to perioperative bleeding and, in particular, to methods of identifying individuals at risk of perioperative bleeding. The present invention relates, in general, to perioperative renal dysfunction and, in particular, to methods of identifying individuals at risk of perioperative renal dysfunction. The present invention relates, in general, to perioperative stroke and, in particular, to methods of identifying individuals at risk of perioperative stroke.
    Type: Application
    Filed: February 29, 2008
    Publication date: March 19, 2009
    Applicant: DUKE UNIVERSITY
    Inventors: Debra A. Schwinn, Ian Welsby, Mihai V. Podgoreanu, Mark Stafford-Smith, Mark F. Newman, Hilary P. Grocott, William D. White, Richard W. Morris, Joseph P. Mathew