Patents by Inventor Joseph P. Nkolola

Joseph P. Nkolola has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biochemically stabilized HIV-1 Env trimer vaccine
    Patent number: 11229696
    Abstract: Stabilized trimers of a clade A strain and a clade C strain of HIV-1 are provided. Broadly neutralizing antisera against HIV-1, methods of making broadly neutralizing antisera against HIV-1, broadly neutralizing vaccines against HIV-1, as well as methods of treating subjects infected with HIV, preventing HIV infection, and inhibiting HIV-mediated activities are also provided.
    Type: Grant
    Filed: April 27, 2020
    Date of Patent: January 25, 2022
    Assignees: Beth Israel Deaconess Medical Center, Inc., Children's Medical Center Corporation
    Inventors: Stephen C. Harrison, Bing Chen, Dan Barouch, Joseph P. Nkolola, Michael Scott Seaman
  • BIOCHEMICALLY STABILIZED HIV-1 ENV TRIMER VACCINE
    Publication number: 20200323976
    Abstract: Stabilized trimers of a clade A strain and a clade C strain of HIV-1 are provided. Broadly neutralizing antisera against HIV-1, methods of making broadly neutralizing antisera against HIV-1, broadly neutralizing vaccines against HIV-1, as well as methods of treating subjects infected with HIV, preventing HIV infection, and inhibiting HIV-mediated activities are also provided.
    Type: Application
    Filed: April 27, 2020
    Publication date: October 15, 2020
    Inventors: Stephen C. HARRISON, Bing CHEN, Dan BAROUCH, Joseph P. NKOLOLA, Michael Scott SEAMAN
  • Biochemically stabilized HIV-1 Env trimer vaccine
    Patent number: 10653770
    Abstract: Stabilized trimers of a clade A strain and a clade C strain of HIV-1 are provided. Broadly neutralizing antisera against HIV-1, methods of making broadly neutralizing antisera against HIV-1, broadly neutralizing vaccines against HIV-1, as well as methods of treating subjects infected with HIV, preventing HIV infection, and inhibiting HIV-mediated activities are also provided.
    Type: Grant
    Filed: September 23, 2019
    Date of Patent: May 19, 2020
    Assignees: Beth Israel Deaconess Medical Center, Inc., Children's Medical Center Corporation
    Inventors: Stephen C. Harrison, Bing Chen, Dan Barouch, Joseph P. Nkolola, Michael Scott Seaman
  • BIOCHEMICALLY STABILIZED HIV-1 ENV TRIMER VACCINE
    Publication number: 20200023056
    Abstract: Stabilized trimers of a clade A strain and a clade C strain of HIV-1 are provided. Broadly neutralizing antisera against HIV-1, methods of making broadly neutralizing antisera against HIV-1, broadly neutralizing vaccines against HIV-1, as well as methods of treating subjects infected with HIV, preventing HIV infection, and inhibiting HIV-mediated activities are also provided.
    Type: Application
    Filed: September 23, 2019
    Publication date: January 23, 2020
    Inventors: Stephen C. HARRISON, Bing CHEN, Dan BAROUCH, Joseph P. NKOLOLA, Michael Scott SEAMAN
  • Biochemically stabilized HIV-1 env trimer vaccine
    Patent number: 10463729
    Abstract: Stabilized trimers of a clade A strain and a clade C strain of HIV-1 are provided. Broadly neutralizing antisera against HIV-1, methods of making broadly neutralizing antisera against HIV-1, broadly neutralizing vaccines against HIV-1, as well as methods of treating subjects infected with HIV, preventing HIV infection, and inhibiting HIV-mediated activities are also provided.
    Type: Grant
    Filed: April 16, 2019
    Date of Patent: November 5, 2019
    Assignees: Beth Israel Deaconess Medical Center, Inc., Children's Medical Center Corporation
    Inventors: Stephen C. Harrison, Bing Chen, Dan H. Barouch, Joseph P. Nkolola, Michael Scott Seaman
  • BIOCHEMICALLY STABILIZED HIV-1 ENV TRIMER VACCINE
    Publication number: 20190240319
    Abstract: Stabilized trimers of a clade A strain and a clade C strain of HIV-1 are provided. Broadly neutralizing antisera against HIV-1, methods of making broadly neutralizing antisera against HIV-1, broadly neutralizing vaccines against HIV-1, as well as methods of treating subjects infected with HIV, preventing HIV infection, and inhibiting HIV-mediated activities are also provided.
    Type: Application
    Filed: April 16, 2019
    Publication date: August 8, 2019
    Inventors: Stephen C. HARRISON, Bing CHEN, Dan H. BAROUCH, Joseph P. NKOLOLA, Michael Scott SEAMAN
  • Biochemically stabilized HIV-1 Env trimer vaccine
    Patent number: 10307478
    Abstract: Stabilized trimers of a clade A strain and a clade C strain of HIV-1 are provided. Broadly neutralizing antisera against HIV-1, methods of making broadly neutralizing antisera against HIV-1, broadly neutralizing vaccines against HIV-1, as well as methods of treating subjects infected with HIV, preventing HIV infection, and inhibiting HIV-mediated activities are also provided.
    Type: Grant
    Filed: March 13, 2018
    Date of Patent: June 4, 2019
    Assignees: Beth Israel Deaconess Medical Center, Inc., Children's Medical Center Corporation
    Inventors: Stephen C. Harrison, Bing Chen, Dan H. Barouch, Joseph P. Nkolola, Michael Scott Seaman
  • BIOCHEMICALLY STABILIZED HIV-1 ENV TRIMER VACCINE
    Publication number: 20180207259
    Abstract: Stabilized trimers of a clade A strain and a clade C strain of HIV-1 are provided. Broadly neutralizing antisera against HIV-1, methods of making broadly neutralizing antisera against HIV-1, broadly neutralizing vaccines against HIV-1, as well as methods of treating subjects infected with HIV, preventing HIV infection, and inhibiting HIV-mediated activities are also provided.
    Type: Application
    Filed: March 13, 2018
    Publication date: July 26, 2018
    Inventors: Stephen C. HARRISON, Bing CHEN, Dan H. BAROUCH, Joseph P. NKOLOLA, Michael Scott SEAMAN
  • Biochemically stabilized HIV-1 ENV trimer vaccine
    Patent number: 9707289
    Abstract: Stabilized trimers of a clade A strain and a clade C strain of HIV-1 are provided. Broadly neutralizing antisera against HIV-1, methods of making broadly neutralizing antisera against HIV-1, broadly neutralizing vaccines against HIV-1, as well as methods of treating subjects infected with HIV, preventing HIV infection, and inhibiting HIV-mediated activities are also provided.
    Type: Grant
    Filed: April 8, 2011
    Date of Patent: July 18, 2017
    Assignees: CHILDREN'S MEDICAL CENTER CORPORATION, NATIONAL INSTITUTES OF HEALTH (NIH), THE UNITED STATES OF AMERICA DEPT. OF HEALTH AND HUMAN SERVICES (DHHS).
    Inventors: Stephen C. Harrison, Bing Chen, Dan C. Barouch, Joseph P. Nkolola, Michael Scott Seaman
  • Biochemically Stabilized HIV-1 ENV Trimer Vaccine
    Publication number: 20120045472
    Abstract: Stabilized trimers of a clade A strain and a clade C strain of HIV-1 are provided. Broadly neutralizing antisera against HIV-1, methods of making broadly neutralizing antisera against HIV-1, broadly neutralizing vaccines against HIV-1, as well as methods of treating subjects infected with HIV, preventing HIV infection, and inhibiting HIV-mediated activities are also provided.
    Type: Application
    Filed: April 8, 2011
    Publication date: February 23, 2012
    Applicants: Beth Israel Deaconess Medical Center, Children's Medical Center Corporation
    Inventors: Stephen C. Harrison, Bing Chen, Dan C. Barouch, Joseph P. Nkolola, Michael Scott Seaman