Patents by Inventor Joseph P. Porcelli

Joseph P. Porcelli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bioreactor for culturing and propagating cells with a woven motionless mixing element
    Patent number: 5565361
    Abstract: A bioreactor, motionless mixing element with attached cells, and method for the enhanced cultivation and propagation of cells in a bioreactor method, and which bioreactor comprises a housing and contains within the housing a motionless mixing element, the attachment of cells to the mixing element and a nutrient composition permitting the cell growth and division of the attached cells, and which motionless mixing element and the method and bioreactor comprise a porous, fibrous sheet material; for example, of a corrugated or knitted, woven wire material, such as stainless steel or titanium, and of selected dimensions as to the fiber diameter and height, to provide a maximum surface area for the attachment of the cells to be cultivated, with the ratio of the fibrous, geometric surface area of the porous, fibrous sheet material to that of a sheet material of the same shape being greater than about 1.0; for example, 1.5, and typically, for example, having a surface area for cell growth of about 2000 to 3000 M.sup.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: October 15, 1996
    Assignee: Koch Engineering Company, Inc.
    Inventors: Michael Mutsakis, Joseph P. Porcelli
  • Bioreactor method of culturing and propagating cells with a woven motionless mixing element
    Patent number: 5476783
    Abstract: A bioreactor, motionless mixing element with attached cells, and method for the enhanced cultivation and propagation of cells in a bioreactor method, and which bioreactor comprises a housing and contains within the housing a motionless mixing element, the attachment of cells to the mixing element and a nutrient composition permitting the cell growth and division of the attached cells, and which motionless mixing element and the method and bioreactor comprise a porous, fibrous sheet material; for example, of a corrugated or knitted, woven wire material, such as stainless steel or titanium, and of selected dimensions as to the fiber diameter and height, to provide a maximum surface area for the attachment of the cells to be cultivated, with the ratio of the fibrous, geometric surface area of the porous, fibrous sheet material to that of a sheet material of the same shape being greater than about 1.0; for example, 1.5, and typically, for example, having a surface area for cell growth of about 2000 to 3000 M.sup.
    Type: Grant
    Filed: August 31, 1993
    Date of Patent: December 19, 1995
    Assignee: Koch Engineering Company, Inc.
    Inventors: Michael Mutsakis, Joseph P. Porcelli