Patents by Inventor Joseph P. Sypek

Joseph P. Sypek has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TRICYCLIC COMPOUNDS AS MATRIX METALLOPROTEINASE INHIBITORS
    Publication number: 20100227859
    Abstract: The present teachings relate to compounds of formula I: and pharmaceutically acceptable salts and esters thereof, wherein R1, R2, R3, R4, X, and Y are as defined herein. The present teachings also provide methods of making the compounds of formula I and methods of inhibiting matrix metalloproteinases, in particular, MMP-12, that may be involved in pathological disorders found in mammals, including a human.
    Type: Application
    Filed: May 5, 2008
    Publication date: September 9, 2010
    Inventors: Wei LI, Jianchang Li, Yuchuan Wu, Junjun Wu, Rajeev Hotchandani, Steve Yikkai Tam, Tarek Suhayl, Joseph P. Sypek, Iain McFadyen
  • Soluble CLCA-1 and antagonists to CLCA-1
    Publication number: 20090214520
    Abstract: The invention relates to methods of treating a disease or condition, wherein expression or activity of soluble CLCA1 is up-regulated, by administering inhibitors of soluble CLCA1. The invention also relates to methods of isolating soluble CLCA1 from a bodily fluid.
    Type: Application
    Filed: August 21, 2008
    Publication date: August 27, 2009
    Inventors: Andrew J. Long, Clive R. Wood, Michael Bowman, Samuel J. Goldman, Joseph P. Sypek
  • Method of treatment using antibody to CLCA-1
    Patent number: 7419664
    Abstract: The invention relates to methods of treating a disease or condition, wherein expression or activity of soluble CLCA1 is up-regulated, by administering inhibitors of soluble CLCA1. The invention also relates to methods of isolating soluble CLCA1 from a bodily fluid.
    Type: Grant
    Filed: May 27, 2004
    Date of Patent: September 2, 2008
    Assignee: Wyeth
    Inventors: Andrew J. Long, Clive R. Wood, Michael Bowman, Samuel J. Goldman, Joseph P. Sypek
  • Soluble CLCA-1 and antagonists to CLCA-1
    Publication number: 20040265314
    Abstract: The invention relates to methods of treating a disease or condition, wherein expression or activity of soluble CLCA1 is up-regulated, by administering inhibitors of soluble CLCA1. The invention also relates to methods of isolating soluble CLCA1 from a bodily fluid.
    Type: Application
    Filed: May 27, 2004
    Publication date: December 30, 2004
    Inventors: Andrew J. Long, Clive R. Wood, Michael Bowman, Samuel J. Goldman, Joseph P. Sypek