Patents by Inventor Joseph P. Yevich

Joseph P. Yevich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Benzisothiazole and benzisoxazole piperazine derivatives
    Patent number: 4411901
    Abstract: Disubstituted N,N-piperazinyl derivatives are disclosed wherein one substituent is benzisothiazol-3-yl or benzisoxazol-3-yl and the other is alkylene attached to heterocycles such as azaspiro[4.5]decanedione, dialkylglutarimide, thiazolidinedione and spirocyclopentylthiazolidinedione or butyrophenone-like groups. The compounds have psychotropic properties and 8-[4-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]butyl]-8-azaspior[4.5]deca ne-7,9-dione is a typical embodiment having selective antipsychotic activity.
    Type: Grant
    Filed: December 23, 1981
    Date of Patent: October 25, 1983
    Assignee: Mead Johnson & Company
    Inventors: Davis L. Temple, Jr., Joseph P. Yevich
  • 2-[4-[(4,4-Dialkyl-2,6-piperidinedion-1-yl)butyl]-1-piperazinyl]pyridines
    Patent number: 4361565
    Abstract: 1-[4-(4,4-Dialkyl-2,6-piperidinedion-1-yl)butyl]piperazines with 2-2-(3-cyano)pyridyl substituents in the 4- position have been synthesized and demonstrate useful psychotropic properties.
    Type: Grant
    Filed: December 28, 1981
    Date of Patent: November 30, 1982
    Assignee: Mead Johnson & Company
    Inventors: Davis L. Temple, Jr., Joseph P. Yevich, Walter G. Lobeck, Jr.
  • N-[(4-Phenyl-1,2,3,6-tetrahydropyridin-1-yl)alkylene]azaspiro alkanediones and N-[(4-hydroxy-4-phenylpiperidin-1-yl)alkylene]azaspiroalkanediones
    Patent number: 4320131
    Abstract: N-[(4-Phenyl-1,2,3,6-tetrahydropyridin-1-yl)alkylene]azaspiroalkanediones having substituents in the phenyl ring have been synthesized and demonstrate useful tranquilizing properties. N-[(4-Hydroxy-4-phenylpiperidin-1-yl)alkylene]azaspiroalkanediones are intermediates in their synthesis.
    Type: Grant
    Filed: March 16, 1981
    Date of Patent: March 16, 1982
    Assignee: Mead Johnson & Company
    Inventors: Davis L. Temple, Jr., Joseph P. Yevich, Walter G. Lobeck, Jr.
  • N-[(4-[3-cyano substituted pyridyl]piperazino)alkyl]-azaspirodecanediones
    Patent number: 4305944
    Abstract: 2-[4-[4-(7,9-Dioxo-8-azaspiro[4.5]decan-8-yl)butyl]-1-piperazinyl]pyridine- 3-carbonitrile, 2-[4-[4-(7,9-dioxo-8-azaspiro-[4.5]decan-8-yl)butyl]-3-methyl-1-piperaziny l]pyridine-3-carbonitrile and 8-[4-[4-(3-methoxy-2-pyridinyl)-1-piperazinyl]butyl]-8-azaspiro-[4.5]decan e-7,9-dione are psychotropic compounds.
    Type: Grant
    Filed: September 8, 1980
    Date of Patent: December 15, 1981
    Assignee: Mead Johnson & Company
    Inventors: Davis L. Temple, Jr., Joseph P. Yevich, Walter G. Lobeck, Jr.
  • Azolopyrimidinones
    Patent number: 4223031
    Abstract: 6-(1H-Tetrazol-5-yl)thiozolo[3,2-a]pyrimidin-5-ones, 3-(1H-tetrazol-5-yl)-4H-pyrimido[2,1-b]benzothiazol-4-ones, and the corresponding imidazo- and triazolo-pyrimidines, thiones, and imines are useful as antiallergy and antiasthmatic compounds by virtue of their inhibitory action on the immediate hypersensitivity reaction in mammals and relaxant action on the tracheal muscle. Intermediates in the synthesis of these substances from 2-aminoazoles and ethoxy-methylene malononitrile also have smooth muscle relaxant and immediate hypersensitivity reaction inhibitory activity.
    Type: Grant
    Filed: May 5, 1978
    Date of Patent: September 16, 1980
    Assignee: Mead Johnson & Company
    Inventors: Robert R. Covington, Davis L. Temple, Jr., Joseph P. Yevich