Abstract: A system for the identification of micro-organisms includes an irradiation unit adapted to sequentially provide coherent electromagnetic radiation of one or more wavelengths along a common optical path. A holder is adapted to retain a substrate having a surface adapted for growth of a micro-organism colony. A beamsplitter is adapted to direct the coherent electromagnetic radiation from the common optical path towards the retained substrate. An imager is arranged opposite the beamsplitter from the retained substrate and is adapted to obtain images of backward-scattered light patterns from the micro-organism colony irradiated by the respective wavelengths of the directed coherent electromagnetic radiation. Some examples provide radiation of multiple wavelengths and include an imager arranged optically downstream of the retained substrate to obtain images of forward-scattered light patterns from the micro-organism colony irradiated by the wavelengths of radiation.

Abstract: The present invention provides formulations of 4-(7-hydroxy-2-isopropyl-4-oxo-4H-quinazolin-3-yl)-benzonitrile (compound I) and methods for treating ocular surface pain by administering such formulations. The present invention also provides methods for treating dry eye disease and ocular hyperemia by administering formulations of 4-(7-hydroxy-2-isopropyl-4-oxo-4H-quinazolin-3-yl)-benzonitrile.

Abstract: Image Signal Processing (ISP) optimization framework for computer vision applications is disclosed. The tuning of the ISP is performed automatically and presented as a nonlinear multi-objective optimization problem, followed by solving the problem using an evolutionary stochastic solver. An improved ISP of the embodiments of the invention includes at least features of search space reduction for reducing a number of ISP configurations, remapping the generated population to the reduced search space via mirroring, and global optimization function processing, which allow tuning all the blocks of the ISP at the same time instead of the prior art tuning of each ISP block separately. Also shown that an ISP tuned for image quality performs inferior compared with an ISP trained for a specific downstream image recognition task.

Abstract: A transmission includes an input shaft coupled to a prime mover, a countershaft, main shaft, and an output shaft, with gears between the countershaft and the main shaft. A shift actuator selectively couples the input shaft to the main shaft by rotatably coupling gears between the countershaft and the main shaft. The shift actuator is mounted on an exterior wall of a housing including the countershaft and the main shaft. A controller controls the shift actuator utilizing an actuating pulse and an opposing pulse.

Abstract: A transmission includes an input shaft coupled to a prime mover, a countershaft, main shaft, and an output shaft, with gears between the countershaft and the main shaft. A shift actuator selectively couples the input shaft to the main shaft by rotatably coupling gears between the countershaft and the main shaft. The shift actuator is mounted on an exterior wall of a housing including the countershaft and the main shaft. A controller controls the shift actuator utilizing an actuating pulse and an opposing pulse.

Abstract: A transmission includes an input shaft coupled to a prime mover, a countershaft, main shaft, and an output shaft, with gears between the countershaft and the main shaft. A shift actuator selectively couples the input shaft to the main shaft by rotatably coupling gears between the countershaft and the main shaft. The shift actuator is mounted on an exterior wall of a housing including the countershaft and the main shaft. A controller controls the shift actuator utilizing an actuating pulse and an opposing pulse.

Abstract: A removable stovetop cover, cut to fit the specific stove, that will cover the entire stovetop, except the burners. It will be sturdy enough to be left in place while cooking, and will contain all cooking splatters. It can then be removed in one piece or sections, to be cleaned in the sink or dishwasher. Once cleaned, it can be reinstalled on the stovetop, eliminating the need to clean the stovetop proper and protecting it's finish from damage. This removable stovetop protector is meant to last the lifetime of the stove.

Abstract: Antimicrobial compositions providing synergistic antimicrobial effects against a variety of bacterial, viral and fungal organisms are described. Methods for using the antimicrobial compositions and products containing the antimicrobial compositions are also described herein.

Abstract: A polymeric nanocarrier and method of treating a bone disease are provided. The polymeric nanocarrier includes an amphiphilic copolymer including a hydrophobic block and a hydrophilic block, where the hydrophilic block comprises a random copolymer. The method of treating a bone disease includes administering the polymeric nanocarrier to a subject in need thereof.

Abstract: A wheelchair assembly that enables an occupant to rotate their self from the seating position to the prone or kneeling prone position so that the occupant may use their arms to better reach and grasp without the aid of another person.

Abstract: Disclosed is a device which incorporates a process by which an absorptive material is used to absorb fluid, the weight of said fluid causes the device to move without any outside energy source. The fluid, by way of evaporation or by being absorbed into another absorptive material, substantially disappears, causing the device to return back to its starting position on its own, and repeat the process. The fluid, which is stocked in a holding area, remains stagnant, until the device in its starting position is made in contact with the fluid by use of a counterweight, and thereby absorbs the fluid, however, when the device is saturated, the greater volume of absorbent on one side causes the device to move to its activated position. In its activated position, the device is not exposed to the fluid and therefore remains until the fluid is evaporated or absorbed into another absorbent. In doing so, the device has converted the potential energy in an unsaturated absorbent into kinetic energy.

Abstract: Multiple full channel quality indication (CQI) reports indicative of received signal quality for multiple carriers in wireless communication are transmitted in multiple time intervals of a CQI channel.

Abstract: A multi-user display collaboration system includes a plurality of source devices that each include a respective source device display screen, a display device, and a sink device coupled to each of the plurality of source devices and the display device. The sink device receives first collaboration information that is stored on the first source device and displayed on a first source device display screen of the first source device, and displays the first collaboration information on the display device. The sink device then receives a first input instruction from a second source device that is directed to the first collaboration information displayed on the display device; and causes the first input instruction to be executed on the first collaboration information that is displayed on the display device.

Abstract: A computer method for correlating depictions of colonies of microorganisms includes receiving an image of a substrate associated with a first time and showing a colony of microorganisms. A second image of the same substrate and associated with a second time shows a candidate colony of microorganisms. A region of the second image that shows the candidate colony of microorganisms is located. The first region of the first image is compared to the second region of the second image. Based on the comparison of the images, the candidate colony of microorganism is determined to be the same colony as the first colony of microorganisms. Systems for moving substrates having colonies of microorganisms and maintaining orientation of the substrates before and after movement are also described.

Abstract: The present invention provides formulations of 4-(7-hydroxy-2-isopropyl-4-oxo-4H-quinazolin-3-yl)-benzonitrile (compound I) and methods for treating ocular surface pain by administering such formulations. The present invention also provides methods for treating dry eye disease and ocular hyperemia by administering formulations of 4-(7-hydroxy-2-isopropyl-4-oxo-4H-quinazolin-3-yl)-benzonitrile.

Abstract: Provided herein are methods of treating a subject with triple negative breast cancer or colorectal cancer. In exemplary embodiments, the method comprises administering to the subject a combination of an oncolytic virus, such as talimogene laherparepvec, and an anti-PD-L1 antibody, such as atezolizumab. In exemplary aspects, the oncolytic virus is administered to the subject at an initial dose followed by a second dose, wherein the initial dose is lower than the second dose. In exemplary aspects, the oncolytic virus is intrahepatically administered to the subject.

Abstract: A grappling dummy having a generally human shape includes a trunk with a head, arms, and legs extending from the trunk. The legs can be connected together by a connecting leg segment forming a leg enclosure. The grappling dummy also includes padding disposed about the trunk, the head, the arms, and the legs. The trunk defines a midline, and the head can extend longitudinally from the trunk angled in a forward direction from the midline at about forty-five degrees. Each of the arms can extend from the trunk at about forty-five degrees. Each of the arms can lie in a generally transverse plane with respect to the midline. Each of the legs can extend from the trunk at about forty-five degrees. Each of the legs can lie in a second plane angled in a forward direction from the midline of the trunk at about forty-five degrees.

Abstract: A transmission includes an input shaft coupled to a prime mover, a countershaft, main shaft, and an output shaft, with gears between the countershaft and the main shaft. A shift actuator selectively couples the input shaft to the main shaft by rotatably coupling gears between the countershaft and the main shaft. The shift actuator is mounted on an exterior wall of a housing including the countershaft and the main shaft. An integrated actuator housing includes a single external power access for the shift actuator. A controller interprets controls the shift actuator with actuating and opposing pulses, and interprets a shaft displacement angle, determines if the transmission is in an imminent zero or zero torque region, and performs a transmission operation in response to the transmission in the imminent zero or zero torque region.

Abstract: A system of spectroscopic devices deployed amongst the fluid infrastructure of hydrocarbon fluids are described herein. The devices provide early visibility into the characteristics of those fluids which inform and educate downstream parties of the potential value of the fluid, or the opportunity to reblend or redirect the fluid to optimize the formulization. By allowing downstream parties to determine the quality and quantity of refined products at an early stage, they are better able to determine the true value of the fluid. The data from the distributed network of spectroscopic analyzers provides valuation information that can be used to make more informed purchasing decisions or allow processors to create blends that optimize the efficiency of refining operations.

Abstract: A system for the characterization of a colony of microorganisms includes a coherent light source configured to provide coherent light of one or more wavelengths along a common optical path. A holder is configured to operationally arrange a substrate so that the colony of microorganisms on a surface of the substrate is positioned to receive the coherent light. Scattered light is generated from the colony of microorganisms receiving coherent light. A first image capture device is configured to receive the scattered light and generate a scatter image from the microorganism colony irradiated by the coherent light. The system also includes a magnifying lens configured to magnify the colony of microorganisms. A second image capture device is configured to capture a light image of the colony of microorganisms magnified by the magnifying lens. Methods of assigning organisms to categories with like organisms without necessarily identifying the organisms are also described.