Patents by Inventor Joseph Pontillo

Joseph Pontillo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Gonadotropin-releasing hormone receptor antagonists and methods relating thereto
    Patent number: 6951858
    Abstract: GnRH receptor antagonists are disclosed which have utility in the treatment of a variety of sex-hormone related conditions in both men and women. The compounds of this invention have the structure: wherein R1, R2, R3a, R3b, R4, R5, and n are as defined herein, including stereoisomers, prodrugs and pharmaceutically acceptable salts thereof. Also disclosed are compositions containing a compound of this invention in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for antagonizing gonadotropin-releasing hormone in a subject in need thereof.
    Type: Grant
    Filed: November 10, 2003
    Date of Patent: October 4, 2005
    Assignee: Neurocrine Biosciences, Inc.
    Inventors: Joseph Pontillo, Zhiqiang Guo, Dongpei Wu
  • Gonadotropin-releasing hormone receptor antagonists and methods relating thereto
    Publication number: 20050075339
    Abstract: GnRH receptor antagonists are disclosed which have utility in the treatment of a variety of sex-hormone related conditions in both men and women. The compounds of this invention have the structure: wherein R1, R2, R3a, R3b, R4, R5, and n are as defined herein, including stereoisomers, prodrugs and pharmaceutically acceptable salts thereof. Also disclosed are compositions containing a compound of this invention in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for antagonizing gonadotropin-releasing hormone in a subject in need thereof.
    Type: Application
    Filed: November 10, 2003
    Publication date: April 7, 2005
    Applicant: Neurocrine Biosciences, Inc.
    Inventors: Joseph Pontillo, Zhiqiang Guo, Dongpei Wu
  • Gonadotropin-releasing hormone receptor antagonists and methods relating thereto
    Publication number: 20040266765
    Abstract: GnRH receptor antagonists are disclosed which have utility in the treatment of a variety of sex-hormone related conditions in both men and women.
    Type: Application
    Filed: April 13, 2004
    Publication date: December 30, 2004
    Applicant: Neurocrine Biosciences, Inc.
    Inventors: Joseph Pontillo, Chen Chen
  • Gonadotropin-releasing hormone receptor antagonists and methods relating thereto
    Patent number: 6740656
    Abstract: GnRH receptor antagonists are disclosed which have utility in the treatment of a variety of sex-hormone related conditions in both men and women. The compounds of this invention have the structure: wherein A, R1, R2, R3a, R3b, R4, R5, R6, and n are as defined herein, including stereoisomers, prodrugs and pharmaceutically acceptable salts thereof. Also disclosed are compositions containing a compound of this invention in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for antagonizing gonadotropin-releasing hormone in a subject in need thereof.
    Type: Grant
    Filed: August 2, 2002
    Date of Patent: May 25, 2004
    Assignee: Neurocrine Biosciences, Inc.
    Inventors: Joseph Pontillo, Chen Chen
  • Ligands of melanocortin receptors and compositions and methods related thereto
    Publication number: 20040053933
    Abstract: Compounds which function as melanocortin receptor ligands and having utility in the treatment of melanocortin receptor-based disorders.
    Type: Application
    Filed: May 9, 2003
    Publication date: March 18, 2004
    Applicant: Neurocrine Biosciences, Inc.
    Inventors: Joseph Pontillo, Dragan Marinkovic, Marion C. Lanier, Joe Anh Tran, Melissa Arellano, Jessica Parker, Jodie Nelson, Chen Chen, Fabio C. Tucci, Caroline Chen, Wanlong Jiang, Nicole White
  • Gonadotropin-releasing hormone receptor antagonists and methods relating thereto
    Patent number: 6673796
    Abstract: GnRH receptor antagonists are disclosed which have utility in the treatment of a variety of sex-hormone related conditions in both men and women. The compounds of this invention have the structure: wherein R1, R2, R3a, R3b, R4, R5, and n are as defined herein, including stereoisomers, prodrugs and pharmaceutically acceptable salts thereof. Also disclosed are compositions containing a compound of this invention in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for antagonizing gonadotropin-releasing hormone in a subject in need thereof.
    Type: Grant
    Filed: August 2, 2002
    Date of Patent: January 6, 2004
    Assignee: Neurocrine Biosciences, Inc.
    Inventors: Joseph Pontillo, Zhiqiang Guo, Dongpei Wu
  • Ligands of melanocortin receptors and compositions and methods related thereto
    Publication number: 20030158209
    Abstract: Compounds which function as melanocortin receptor ligands and having utility in the treatment of melanocortin receptor-based disorders.
    Type: Application
    Filed: October 9, 2002
    Publication date: August 21, 2003
    Applicant: Neurocrine Biosciences Inc.
    Inventors: Brian P. Dyck, Val Goodfellow, Teresa Phillips, Jessica Parker, Xiaohu Zhang, Chen Chen, Joe Anh Tran, Joseph Pontillo, Fabio C. Tucci
  • Gonadotropin-releasing hormone receptor antagonists and methods relating thereto
    Publication number: 20030114455
    Abstract: GnRH receptor antagonists are disclosed which have utility in the treatment of a variety of sex-hormone related conditions in both men and women.
    Type: Application
    Filed: August 2, 2002
    Publication date: June 19, 2003
    Applicant: Neurocrine Biosciences, Inc.
    Inventors: Joseph Pontillo, Zhiqiang Guo, Dongpei Wu
  • Gonadotropin-releasing hormone receptor antagonists and methods relating thereto
    Publication number: 20030109535
    Abstract: GnRH receptor antagonists are disclosed which have utility in the treatment of a variety of sex-hormone related conditions in both men and women.
    Type: Application
    Filed: August 2, 2002
    Publication date: June 12, 2003
    Applicant: Neurocrine Biosciences, Inc.
    Inventors: Joseph Pontillo, Chen Chen