Patents by Inventor Joseph R. Day

Joseph R. Day has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Phospholipid transfer proteins and DNA encoding them
    Patent number: 5622843
    Abstract: Isolated polynucleotide molecules encoding mammalian phospholipid transfer proteins (PLTP) and phospholipid transfer protein polypeptides are disclosed. The DNA molecules are transformed or transfected into host cells and the cells cultured to produce recombinant PLTP and PLTP polypeptides. PLTP and PLTP polypeptides may be combined with a pharmaceutically acceptable vehicle and administered to patients to regulate phospholipid transfer activity and thereby obtain a more favorable lipoprotein profile in the blood. The proteins and polypeptides may also be used within methods to measure phospholipid transfer activity or identify inhibitors of phospholipid transfer activity.
    Type: Grant
    Filed: December 30, 1993
    Date of Patent: April 22, 1997
    Assignees: Zymogenetics, Inc., University of Washington
    Inventors: Joseph R. Day, John J. Albers, Catherine E. Lofton-Day, Janet L. Adolphson
  • Methods of detecting phospholipid transfer activity and kits therefor
    Patent number: 5610019
    Abstract: Isolated polynucleotide molecules encoding mammalian phospholipid transfer proteins (PLTP) and phospholipid transfer protein polypeptides are disclosed. The DNA molecules are transformed or transfected into host cells and the cells cultured to produce recombinant PLTP and PLTP polypeptides. PLTP and PLTP polypeptides may be combined with a pharmaceutically acceptable vehicle and administered to patients to regulate phospholipid transfer activity and thereby obtain a more favorable lipoprotein profile in the blood. The proteins and polypeptides may also be used within methods to measure phospholipid transfer activity or identify inhibitors of phospholipid transfer activity.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: March 11, 1997
    Assignee: ZymoGenetics, Inc.
    Inventors: Joseph R. Day, John J. Albers, Catherine E. Lofton-Day, Janet L. Adolphson