Abstract: An electrical system comprises a flexible circuit (FC) comprising at least one conductive circuit trace disposed within or between one or more dielectric layers and defining at least one exposed conductive circuit trace portion, an electrical device system comprising an electrical device disposed within a housing and at least one conductive terminal electrically connected to the electrical device and that extend substantially to an end of the housing, and an electrical connector configured to physically secure and electrically connect the at least one exposed conductive circuit trace portion to the at least one conductive terminal of the electrical device system, wherein the electrical connector and the housing of the electrical device system define at least one connection feature for physically securing to each other.

Abstract: A system for ultrasound interrogation of a lung including a memory, an electromagnetic (EM) board, an extended working channel (EWC), an EM sensor, a US transducer, and a processor. The memory stores a three dimensional (3D) model and pathway plan for navigating a luminal network. The EM board generates an EM field. The EWC is configured to navigate the luminal network toward a target following the pathway plan. The EM sensor extends distally from a distal end of the EWC and is configured to sense the EM field. The US transducer extends distally from a distal end of the EWC, generates US waves, and receives US waves reflected from the luminal network. The processor processes the sensed EM field to synchronize a location of the EM sensor in the 3D model, to process the reflected US waves to generate images, or to integrate the generated images with the 3D model.

Abstract: A system for ultrasound interrogation of a lung includes a memory, an electromagnetic (EM) board, an extended working channel (EWC), an EM sensor, a US transducer, and a processor. The memory stores a three dimensional (3D) model, a pathway plan for navigating a luminal network. An EM board generates an EM field. The EWC is configured to navigate the luminal network of a patient toward a target following the pathway plan and the EM sensor extends distally from the EWC and senses the EM field. The US transducer extends distally from a distal end of the EWC and generates US waves and receives US waves reflected from the luminal network and the processor processes the sensed EM field to synchronize a location of the EM sensor in the 3D model, to process the reflected US waves to generate images, or to integrate the generated images with the 3D model.

Abstract: Three-dimensional modeling of patient-specific tumors. In an embodiment, patient-specific data, representing a tumor microenvironment and one or more metrics, are received. A patient-specific spatial model, representing the tumor microenvironment as a lattice comprising a plurality of elastic material points, is generated from the patient-specific data. Patient-specific drug interaction and metabolism models are also determined. The tumor microenvironment is then simulated, for one or more drug interventions, through a plurality of iterations in which each elastic material point is updated in each iteration based on computations of chemical diffusion, biochemical reactions, metabolism, drug interactions, growth and death, and mechanical forces. A report, comprising a three-dimensional representation of the patient-specific spatial model after one or more iterations, is generated for the drug intervention(s).

Abstract: Three-dimensional modeling of patient-specific tumors. In an embodiment, patient-specific data, representing a tumor microenvironment and one or more metrics, are received. A patient-specific spatial model, representing the tumor microenvironment as a lattice comprising a plurality of elastic material points, is generated from the patient-specific data. Patient-specific drug interaction and metabolism models are also determined. The tumor microenvironment is then simulated, for one or more drug interventions, through a plurality of iterations in which each elastic material point is updated in each iteration based on computations of chemical diffusion, biochemical reactions, metabolism, drug interactions, growth and death, and mechanical forces. A report, comprising a three-dimensional representation of the patient-specific spatial model after one or more iterations, is generated for the drug intervention(s).

Abstract: Three-dimensional modeling of patient-specific tumors. In an embodiment, patient-specific data, representing a tumor microenvironment and one or more metrics, are received. A patient-specific spatial model, representing the tumor microenvironment as a lattice comprising a plurality of elastic material points, is generated from the patient-specific data. Patient-specific drug interaction and metabolism models are also determined. The tumor microenvironment is then simulated, for one or more drug interventions, through a plurality of iterations in which each elastic material point is updated in each iteration based on computations of chemical diffusion, biochemical reactions, metabolism, drug interactions, growth and death, and mechanical forces. A report, comprising a three-dimensional representation of the patient-specific spatial model after one or more iterations, is generated for the drug intervention(s).

Abstract: Three-dimensional modeling of patient-specific tumors. In an embodiment, patient-specific data, representing a tumor microenvironment and one or more metrics, are received. A patient-specific spatial model, representing the tumor microenvironment as a lattice comprising a plurality of elastic material points, is generated from the patient-specific data. Patient-specific drug interaction and metabolism models are also determined. The tumor microenvironment is then simulated, for one or more drug interventions, through a plurality of iterations in which each elastic material point is updated in each iteration based on computations of chemical diffusion, biochemical reactions, metabolism, drug interactions, growth and death, and mechanical forces. A report, comprising a three-dimensional representation of the patient-specific spatial model after one or more iterations, is generated for the drug intervention(s).

Abstract: Three-dimensional modeling of patient-specific tumors. In an embodiment, patient-specific data, representing a tumor microenvironment and one or more metrics, are received. A patient-specific spatial model, representing the tumor microenvironment as a lattice comprising a plurality of elastic material points, is generated from the patient-specific data. Patient-specific drug interaction and metabolism models are also determined. The tumor microenvironment is then simulated, for one or more drug interventions, through a plurality of iterations in which each elastic material point is updated in each iteration based on computations of chemical diffusion, biochemical reactions, metabolism, drug interactions, growth and death, and mechanical forces. A report, comprising a three-dimensional representation of the patient-specific spatial model after one or more iterations, is generated for the drug intervention(s).

Abstract: A process is provided for removing vapor phase selenium species produced by the combustion of selenium and sulfur-containing fuel of the kind used to generate electric power in conjunction with a flue gas desulfurization process. In one process embodiment the flue gas leaving the combustion system is humidified by the injection of atomized water or a dilute alkaline slurry at a selected location upstream of the flue gas desulfurization system to cool the flue gas from a temperature of about 300.degree. F. to a temperature of about 280.degree. F. so as to enhance the selenium removal efficiency. In another process embodiment the flue gas leaving the combustion system is first humidified to cool the flue gas from a temperature of about 300.degree. F. to a temperature of about 200.degree. F. so as to enhance the selenium removal efficiency, and then an alkaline sorbent material is injected into the humidified flue gas.