Abstract: An implant comprises a unitary body including an intramedullary portion connected to an extramedullary portion. The unitary body is configured to attach a first bone section to a second bone section. The intramedullary portion has a first longitudinal axis, and is configured for insertion into the first bone section. The intramedullary portion includes at least one first fastener aperture having an aperture axis oriented obliquely relative to the first longitudinal axis. The extramedullary portion is configured to abut a surface of the second bone section and includes at least one second fastener aperture disposed to transversely receive a bone fastener inserted in the second bone section. The extramedullary portion has a second longitudinal axis offset from, the first longitudinal axis.

Abstract: Disclosed example radiographic source exposure devices include: a radiographic source capsule having a radionuclide; a radiographic shield; a channel within the radiographic shield, the channel having a first end and a second end; and a replaceable tube configured to guide a radiographic source capsule between a stored position and an exposed position in which at least a portion of the radiographic source capsule is exposed to an exterior of the radiographic shield.

Abstract: A congested network link is identified. Applications that are contributing to the congestion are also identified. The contribution of each of the identified applications to the congestion is then determined in order to determine whether the application's usage of the network should be throttled. A control signal is generated in order to indicate to the application that it is to perform an application-specific throttling operation to reduce the network bandwidth consumed by the application. If the application-specific throttling does not sufficiently reduce network congestion, a more aggressive throttling operation is performed.

Abstract: A targeting guide is disclosed includes a handle extending substantially along a longitudinal axis. The longitudinal handle defines one or more burr holes extending from a first side of the handle to a second side of the handle. A head is coupled to a distal end of the longitudinal handle. The head defines a plurality of guide holes sized and configured to receive a k-wire therethrough.

Abstract: An implant comprises a unitary body including an intramedullary portion connected to an extramedullary portion. The unitary body is configured to attach a first bone section to a second bone section. The intramedullary portion has a first longitudinal axis, and is configured for insertion into the first bone section. The intramedullary portion includes at least one first fastener aperture having an aperture axis oriented obliquely relative to the first longitudinal axis. The extramedullary portion is configured to abut a surface of the second bone section and includes at least one second fastener aperture disposed to transversely receive a bone fastener inserted in the second bone section. The extramedullary portion has a second longitudinal axis offset from, the first longitudinal axis.

Abstract: A targeting guide is disclosed includes a handle extending substantially along a longitudinal axis. The longitudinal handle defines one or more burr holes extending from a first side of the handle to a second side of the handle. A head is coupled to a distal end of the longitudinal handle. The head defines a plurality of guide holes sized and configured to receive a k-wire therethrough.

Abstract: An example radiographic source exposure device includes: a housing; a radiographic source capsule within the housing, the radiographic source capsule having a radionuclide; a shield within the housing and configured to shield the radiographic source capsule and to permit extension of the radiographic source capsule to expose the radiographic source capsule; one or more sensors coupled to the housing, the one or more sensors configured to detect sensor data comprising one or more of: a count of exposure cycles, a length between the radiographic source capsule position and a stored position, a surface dose, a source decay of the radiographic source, a locking device locking mode status, an unlocking key status, a radiographic source exposure device orientation, a particulate count within the shield, a shock event, or shield wear; a processing system within the housing and configured to store the sensor data and output the sensor data; and a power source within the housing and configured to provide power to the

Abstract: A targeting guide is disclosed includes a handle extending substantially along a longitudinal axis. The longitudinal handle defines one or more burr holes extending from a first side of the handle to a second side of the handle. A head is coupled to a distal end of the longitudinal handle. The head defines a plurality of guide holes sized and configured to receive a k-wire therethrough.

Abstract: Systems and methods are disclosed for applying neural networks in resource-constrained environments. A system may include a sensor located in a resource-constrained environment configured to generate sensor data of the resource-constrained environment. The system may also include a first computing device not located in the resource-constrained environment configured to produce a neural network structure based on the sensor data. The system may further include a second computing device located in the resource-constrained environment configured to provide the sensor data as input to the neural network structure. The second computing device may be further configured to determine a state of the resource-constrained environment based on the input of the sensor data to the neural network structure.

Abstract: An example portable radiography scanning system includes: a radiation detector configured to generate digital radiography images based on incident radiation; a radiation emitter configured to output the radiation; and a computing device configured to: receive the digital radiography images from the radiation detector; compensate one or more of the digital radiography images for variations in magnification of the digital radiography images; and store one or more compensated radiography images based on the magnification compensation and associated with physical location information.

Abstract: A system and method for performing a percutaneous bunionectomy. The system including a jig, which subsequent to attachment and performance of an osteotomy on the bone, uses a rack and pinion mechanism to translate the separated portion of the bone to a surgeon determined displacement ?. A locking mechanism maintains the desired displacement of the bone portions and allows the surgeon, with use of an attached visual guide, to insert a k-wire through the bone portions to serve as a guide wire for the internal fixation that maintains the displacement during the healing. The system removes the requirement that the surgeon manually maintain the desired displacement while inserting the guide wire.

Abstract: An alignment device includes a first member, a second member, and a guide. The first member has an elongated body and is configured to be at least partially inserted into a canal in a first bone portion. The second member includes a body attachable to the first member and an arm extending from the body. The arm defines a track. The guide is configured to translate along the track defined by the arm. The guide includes an aperture configured to receive an alignment member therethrough. The guide is configured to be positioned at a desired position along the track to allow insertion of the at least one alignment member through the aperture and into the first bone portion at a desired trajectory.

Abstract: In some examples, a simulator system may simulate one or more minimally invasive surgery (MIS) procedures associated with bone removal. The simulator system comprises an input device configured to detect a position of a portion of a user tool relative to an operation envelope, a simulation device defining one or more surfaces that define one or more boundaries for a movement of the user tool relative to the operation envelope during a simulated surgical procedure, and processing circuitry. The processing circuitry is configured to receive, from the input device, information indicative of the position of at least the portion of the user tool relative to the operational envelope, generate a performance metric based on the position of at least the portion of the user tool relative to the operational envelope over a period of time, and output, for display to a user, the performance metric.

Abstract: A planter includes a wall and a rim formed at an open end portion of the wall. A set of holes is formed through the wall and is disposed on a surface beneath the rim. The surface beneath the rim includes a shape to obscure a view of the hole below the rim.

Abstract: Provided are compositions and methods for reducing off-target toxicity of antibody-drug conjugates (ADCs). The compositions comprise an ADC, and an agent targeted to the drug (payload) that is delivered by or derived from the ADC. The ADC and the agent targeted to the payload may be delivered together or separately in the treatment of various conditions (such as tumors) by ADCs. Examples of agents targeted to payload include antibodies, fragments, or modifications thereof.

Abstract: Systems and methods are disclosed for applying neural networks in resource-constrained environments. A system may include a sensor located in a resource-constrained environment configured to generate sensor data of the resource-constrained environment. The system may also include a first computing device not located in the resource-constrained environment configured to produce a neural network structure based on the sensor data. The system may further include a second computing device located in the resource-constrained environment configured to provide the sensor data as input to the neural network structure. The second computing device may be further configured to determine a state of the resource-constrained environment based on the input of the sensor data to the neural network structure.

Abstract: A targeting guide is disclosed includes a handle extending substantially along a longitudinal axis. The longitudinal handle defines one or more burr holes extending from a first side of the handle to a second side of the handle. A head is coupled to a distal end of the longitudinal handle. The head defines a plurality of guide holes sized and configured to receive a k-wire therethrough.

Abstract: Surgical instruments, such as distractors and methods of manufacture are provided for maintaining a displacement of bone determined to be necessary by a surgeon. For instance, a surgical distractor may include a first holder section, a second holder section, a first displacement element, a second displacement element, a positioning element, and a rotatable component having an opening. The second holder section may be coupled to the first holder section using one or more coupling elements coupled to both the first holder section and the second holder section. The first displacement element and the positioning element may be positioned on the first holder section and the second displacement element and the rotatable opening may be positioned on the second holder section configured to engage the first displacement element.

Abstract: The disclosure is directed to methods for transmitting vibrations via an electronic and/or transducer assembly through a user or wearer's tooth, teeth, jaw, and/or other bones. The disclosure is further directed to a system for transmitting vibrations via an electronic and/or transducer assembly through a user or wearer's tooth, teeth, jaw and/or other bones. The disclosure is further directed to an oral apparatus for implementation of methods and systems described herein.