Patents by Inventor Joseph Scibona
Joseph Scibona has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20200005479Abstract: Described are embodiments that include methods and devices for detecting disposables that may be used in medical devices. Embodiments involve the detection of disposables used in apheresis machines. The disposable are configured to fit into portions, or features, of the apheresis machines in predetermined ways and embodiments provide for detecting whether the disposable have been loaded correctly.Type: ApplicationFiled: April 14, 2017Publication date: January 2, 2020Inventors: Briden Ray STANTON, Brett Michael BAEVERSTAD, Joseph A. SCIBONA, Minh Anh Thi NGUYEN, Megan A. RIVES
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Patent number: 8241196Abstract: The invention relates to apparatus for controlling the processing of blood into blood components, particularly components for stroboscopic LED light sources for centrifuges. A digital control circuit controls a high amperage linear voltage regulator. The voltage regulator charges a capacitor bank, which in turn powers LED light sources. The digital control circuit comprises an N-channel switched mode FET. The switched mode FET receives a pulsed digital signal from the microprocessor controlling the blood processing apparatus. A by-pass resistor in parallel with the FET allows most of the current to flow past the FET, thus minimizes heating of the FET. The performance of the FET, therefore, remains stable despite extended use of the apparatus.Type: GrantFiled: December 4, 2009Date of Patent: August 14, 2012Assignee: Terumo BCT, Inc.Inventor: Joseph A. Scibona
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Patent number: 8057376Abstract: A centrifugal blood separation apparatus having an optical camera control system with a focused, stationary light source. A diffusion plate mounted on a rotor, rather than on or near the light source, allows an intense light beam to be transmitted from the light source to the rotor and then diffused at the rotor across an observation region. Different characteristics of a diffusion surface allow different lighting regions within the observation region. The diffusion plate has upper and lower plates with a diffusion surface sealed between the plates. This prevents degradation or contamination of the diffusion surface by abrasion, dirt, blood components or other materials that might incidentally contact the diffusion surface.Type: GrantFiled: September 30, 2008Date of Patent: November 15, 2011Assignee: CaridianBCT, Inc.Inventors: James R. Ladtkow, Joseph A. Scibona, Jeremy Kolenbrander
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Patent number: 7943916Abstract: The invention relates generally to methods of monitoring and controlling the processing of blood and blood samples, particularly the separation of blood and blood samples into its components with a two-dimensional optical measurement and control device. The method may comprise the steps of providing a blood processing system comprising a density centrifuge blood processing system and an elutriation blood processing system; filling the elutriation blood processing system with a desired component; measuring a cellular flux of cells entering the elutriation blood processing system with a two-dimensional optical control system; and flushing the elutriation blood processing system.Type: GrantFiled: September 17, 2009Date of Patent: May 17, 2011Assignee: CaridianBCT, Inc.Inventors: Lee F. Carter, Jeremy P. Kolenbrander, James R. Ladtkow, Joseph A. Scibona, Jeffrey A. Steward, Chris Fletcher
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Patent number: 7906771Abstract: The invention relates generally to methods of monitoring and controlling the processing of blood and blood samples, particularly the separation of blood and blood samples into its components. In one aspect, the invention relates to optical methods for measuring two-dimensional distributions of transmitted light intensities, scattered light intensities or both from a separation chamber of a density centrifuge. The method may include performing first and second measurements of an operating condition; analyzing the first and second measurements using a predictive data analysis algorithm; comparing the predicted operating condition to a desired operating condition; and adjusting at least one setting.Type: GrantFiled: September 17, 2009Date of Patent: March 15, 2011Assignee: CaridianBCT, Inc.Inventors: Lee F. Carter, Jeremy P. Kolenbrander, James R. Ladtkow, Joseph A. Scibona, Jeffrey A. Steward, Chris Fletcher
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Publication number: 20100160137Abstract: A centrifuge for separating blood and blood components having a blood processing vessel mounted on a rotor of a centrifuge. A sensor in the outflow race of a return peristaltic pump detects air bubbles in the fluid within a return loop. The sensor may be a sonic sensor, a sonic pulse echo sensor, or capacitive plates. A pre-determined minimum bubble size or sizes or a cumulative volume may be selected, and the device operator may be warned only of the existence of bubbles that exceed a certain size or of a cumulative volume of bubbles, or the blood donation procedure may be stopped if a bubble exceeds a certain critical size or if a pre-determined volume of bubbles over a certain period or volume of fluid is exceeded.Type: ApplicationFiled: December 9, 2009Publication date: June 24, 2010Applicant: CARIDIANBCT, INC.Inventors: Joseph A. SCIBONA, David GIBBONS, John R. LINDNER, William PALSULICH
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Publication number: 20100160134Abstract: The invention relates to apparatus for controlling the processing of blood into blood components, particularly components for stroboscopic LED light sources for centrifuges. A digital control circuit controls a high amperage linear voltage regulator. The voltage regulator charges a capacitor bank, which in turn powers LED light sources. The digital control circuit comprises an N-channel switched mode FET. The switched mode FET receives a pulsed digital signal from the microprocessor controlling the blood processing apparatus. A by-pass resistor in parallel with the FET allows most of the current to flow past the FET, thus minimizes heating of the FET. The performance of the FET, therefore, remains stable despite extended use of the apparatus.Type: ApplicationFiled: December 4, 2009Publication date: June 24, 2010Applicant: CARIDIANBCT, INC.Inventor: Joseph A. SCIBONA
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Publication number: 20100025336Abstract: The invention relates generally to methods of monitoring and controlling the processing of blood and blood samples, particularly the separation of blood and blood samples into its components. In one aspect, the invention relates to optical methods for measuring two-dimensional distributions of transmitted light intensities, scattered light intensities or both from a separation chamber of a density centrifuge. The method may include performing first and second measurements of an operating condition; analyzing the first and second measurements using a predictive data analysis algorithm; comparing the predicted operating condition to a desired operating condition; and adjusting at least one setting.Type: ApplicationFiled: September 17, 2009Publication date: February 4, 2010Applicant: CARIDIANBCT, INC.Inventors: Lee F. CARTER, Jeremy P. KOLENBRANDER, James R. LADTKOW, Joseph A. SCIBONA, Jeffrey A. STEWARD, Chris FLETCHER
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Publication number: 20100012592Abstract: The invention relates generally to methods of monitoring and controlling the processing of blood and blood samples, particularly the separation of blood and blood samples into its components with a two-dimensional optical measurement and control device. The method may comprise the steps of providing a blood processing system comprising a density centrifuge blood processing system and an elutriation blood processing system; filling the elutriation blood processing system with a desired component; measuring a cellular flux of cells entering the elutriation blood processing system with a two-dimensional optical control system; and flushing the elutriation blood processing system.Type: ApplicationFiled: September 17, 2009Publication date: January 21, 2010Applicant: CARIDIANBCT, INC.Inventors: Lee F. CARTER, Jeremy P. KOLENBRANDER, James R. LADTKOW, Joseph A. SCIBONA, Jeffrey A. STEWARD, Chris FLETCHER
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Patent number: 7605388Abstract: The invention relates to an optical cell for a separation chamber of a density centrifuge blood processing system for separating fluid components comprising an extraction chamber having a first external optical surface for transmitting at least a portion of an incident optical beam; and an extraction port having an axial bore for passing fluid components and a first external optical surface for transmitting at least a portion of the incident optical beam; wherein said first external optical surface of said extraction chamber and said first external optical surface of said extraction port are both positioned within the depth of field of a light collection element.Type: GrantFiled: July 7, 2008Date of Patent: October 20, 2009Assignee: CaridianBCT, Inc.Inventors: Lee F. Carter, Jeremy P. Kolenbrander, James R. Ladtkow, Joseph A. Scibona, Jeffrey A. Steward, Chris Fletcher
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Publication number: 20090156383Abstract: A centrifugal blood separation apparatus having an optical camera control system with a focused, stationary light source. A diffusion plate mounted on a rotor, rather than on or near the light source, allows an intense light beam to be transmitted from the light source to the rotor and then diffused at the rotor across an observation region. Different characteristics of a diffusion surface allow different lighting regions within the observation region. The diffusion plate has upper and lower plates with a diffusion surface sealed between the plates. This prevents degradation or contamination of the diffusion surface by abrasion, dirt, blood components or other materials that might incidentally contact the diffusion surface.Type: ApplicationFiled: September 30, 2008Publication date: June 18, 2009Applicant: CARIDIANBCT, INC.Inventors: James R. LADTKOW, Joseph A. SCIBONA, Jeremy KOLENBRANDER
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Publication number: 20080283781Abstract: The invention relates to an optical cell for a separation chamber of a density centrifuge blood processing system for separating fluid components comprising an extraction chamber having a first external optical surface for transmitting at least a portion of an incident optical beam; and an extraction port having an axial bore for passing fluid components and a first external optical surface for transmitting at least a portion of the incident optical beam; wherein said first external optical surface of said extraction chamber and said first external optical surface of said extraction port are both positioned within the depth of field of a light collection element.Type: ApplicationFiled: July 7, 2008Publication date: November 20, 2008Applicant: GAMBRO BCT, INC.Inventors: Lee F. CARTER, Jeremy P. KOLENBRANDER, James R. LADTKOW, Joseph A. SCIBONA, Jeffrey A. STEWARD, Chris FLETCHER
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Patent number: 7422693Abstract: The invention relates generally to methods of monitoring and controlling the processing of blood and blood samples, particularly the separation of blood and blood samples into its components. In one aspect, the invention relates to optical methods, devices and device components for measuring two-dimensional distributions of transmitted light intensities, scattered light intensities or both from a separation chamber of a density centrifuge. In embodiment, two-dimensional distributions of transmitted light intensities, scattered light intensities or both measured by the methods of the present invention comprise images of a separation chamber or component thereof, such as an optical cell of a separation chamber. In another aspect, the present invention relates to multifunctional monitoring and control systems for blood processing, particularly blood processing via density centrifugation.Type: GrantFiled: July 1, 2004Date of Patent: September 9, 2008Assignee: Caridianbct, Inc.Inventors: Lee F. Carter, Jeremy P. Kolenbrander, James R. Ladtkow, Joseph A. Scibona, Jeffrey A. Steward, Chris Fletcher
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Patent number: 7355685Abstract: The invention relates to apparatus for controlling the processing of blood into blood components, particularly components for stroboscopic LED light sources for centrifuges. The stroboscopic apparatus comprises a first light source with reflective surfaces spaced around a central illumination axis, and light-emitting diodes spaced away from the axis radially outward from the reflective surfaces. An additional light source comprises a modified parabolic reflector surrounding a light emitting diode, the parabolic reflector having walls spaced outwardly from an axis of symmetry such that focal points fall radially outwardly from a center of the LED, forming a circular focal area. A controller that energizes the diodes for selected periods of time comprises a pair of switches connected in series, with an LED connected between the switches. One of the switches is connected to ground and is closed at the end of a period of illumination.Type: GrantFiled: October 5, 2007Date of Patent: April 8, 2008Assignee: Gambro BCT, Inc.Inventors: Joseph A. Scibona, Shannon Durkee
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Patent number: 7327443Abstract: The invention relates to apparatus for controlling the processing of blood into blood components, particularly components for stroboscopic LED light sources for centrifuges. The stroboscopic apparatus comprises a first light source with reflective surfaces spaced around a central illumination axis, and light-emitting diodes spaced away from the axis radially outward from the reflective surfaces. An additional light source comprises a modified parabolic reflector surrounding a light emitting diode, the parabolic reflector having walls spaced outwardly from an axis of symmetry such that focal points fall radially outwardly from a center of the LED, forming a circular focal area. A controller that energizes the diodes for selected periods of time comprises a pair of switches connected in series, with an LED connected between the switches. One of the switches is connected to ground and is closed at the end of a period of illumination.Type: GrantFiled: December 29, 2004Date of Patent: February 5, 2008Assignee: Gambro BCT, IncInventors: Joseph A. Scibona, Shannon Durkee
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Publication number: 20080024757Abstract: The invention relates to apparatus for controlling the processing of blood into blood components, particularly components for stroboscopic LED light sources for centrifuges. The stroboscopic apparatus comprises a first light source with reflective surfaces spaced around a central illumination axis, and light-emitting diodes spaced away from the axis radially outward from the reflective surfaces. An additional light source comprises a modified parabolic reflector surrounding a light emitting diode, the parabolic reflector having walls spaced outwardly from an axis of symmetry such that focal points fall radially outwardly from a center of the LED, forming a circular focal area. A controller that energizes the diodes for selected periods of time comprises a pair of switches connected in series, with an LED connected between the switches. One of the switches is connected to ground and is closed at the end of a period of illumination.Type: ApplicationFiled: October 5, 2007Publication date: January 31, 2008Applicant: GAMBRO BCT, INC.Inventors: Joseph SCIBONA, Shannon DURKEE
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Publication number: 20060001860Abstract: The invention relates to apparatus for controlling the processing of blood into blood components, particularly components for stroboscopic LED light sources for centrifuges. The stroboscopic apparatus comprises a first light source with reflective surfaces spaced around a central illumination axis, and light-emitting diodes spaced away from the axis radially outward from the reflective surfaces. An additional light source comprises a modified parabolic reflector surrounding a light emitting diode, the parabolic reflector having walls spaced outwardly from an axis of symmetry such that focal points fall radially outwardly from a center of the LED, forming a circular focal area. A controller that energizes the diodes for selected periods of time comprises a pair of switches connected in series, with an LED connected between the switches. One of the switches is connected to ground and is closed at the end of a period of illumination.Type: ApplicationFiled: December 29, 2004Publication date: January 5, 2006Applicant: GAMBRO, INC.Inventors: Joseph Scibona, Shannon Durkee
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Publication number: 20050051466Abstract: The invention relates generally to methods of monitoring and controlling the processing of blood and blood samples, particularly the separation of blood and blood samples into its components. In one aspect, the invention relates to optical methods, devices and device components for measuring two-dimensional distributions of transmitted light intensities, scattered light intensities or both from a separation chamber of a density centrifuge. In embodiment, two-dimensional distributions of transmitted light intensities, scattered light intensities or both measured by the methods of the present invention comprise images of a separation chamber or component thereof, such as an optical cell of a separation chamber. In another aspect, the present invention relates to multifunctional monitoring and control systems for blood processing, particularly blood processing via density centrifugation.Type: ApplicationFiled: July 1, 2004Publication date: March 10, 2005Inventors: Lee Carter, Jeremy Kolenbrander, James Ladtkow, Joseph Scibona, Jeffrey Steward, Chris Fletcher
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Patent number: 5720741Abstract: A venous reservoir bag subassembly is provided which is adapted to cooperate with a mounting assembly having a bracket frame and a front plate reproducibly relatively movable to enable constant accurate blood volume readout, cooperating means between the subassembly and the mounting assembly to provide against unduly low blood volume, and angled conduit means cooperating with the bag and recesses in the subassembly and assembly to provide further failsafe against passage of the undesirable gas.Type: GrantFiled: June 7, 1995Date of Patent: February 24, 1998Assignee: Cobe Laboratories, Inc.Inventors: Rodger L. Stewart, William D. Dalke, Joseph A. Scibona, Barry D. Reed, John T. Buckley
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Patent number: 5693039Abstract: A venous reservoir bag subassembly which is adapted to cooperate with a mounting assembly having a bracket frame and a front plate reproducibly relatively movable to enable constant accurate blood volume readout, a cooperating mechanism between the subassembly and the mounting assembly to provide against unduly low blood volume, and an angled conduit cooperating with the bag and recesses in the subassembly and assembly to provide further failsafe against passage of the undesirable gas.Type: GrantFiled: February 2, 1994Date of Patent: December 2, 1997Assignee: Cobe Laboratories, Inc.Inventors: Rodger L. Stewart, John T. Buckley, William D. Dalke, Barry D. Reed, Joseph A. Scibona