Abstract: The invention provides antibodies, and antigen-binding fragments thereof, that specifically bind to CXCR5. The antibodies can be afucosylated and exhibit increased ADCC compared with the otherwise identical fucosylated antibodies. The invention includes uses, and associated methods of using the antibodies.

Abstract: Disclosed are a method and system for propagating data changes in a hierarchy of dataset models in which each dataset model comprises an analytic and one or more parent datasets, including a primordial dataset. The analytic is executed to instantiate a first instance of the data model. After a change in a primordial dataset, each instance of a dataset model that descends from the primordial dataset is invalidated, and the analytic is re-executed to create a second instance of the data model. Analytical results may be displayed. The first dataset model may include a metric in which the definition of the metric comprises metadata of the dataset model. Metric values may be stored in a first cache, re-computed on a new instance of the dataset model, and stored in a second cache.

Abstract: A modular electrical connector with separately shielded signal conductor pairs. The connector may be assembled from modules, each containing a pair of signal conductors with surrounding partially or fully conductive material. Modules of different sizes may be assembled into wafers, which are then assembled into a connector. Wafers may include lossy material. In some embodiments, shielding members of two mating connectors may each have compliant members along their distal portions, such that, the shielding members engage at points of contact at multiple locations, some of which are adjacent the mating edge of each of the mating shielding members.

Abstract: An insertion instrument is configured to eject at least one anchor body into respective target locations, and subsequently apply a predetermined tensile force at least one actuation member of the at least one anchor member so as to actuate the at least one anchor body from a first configuration to a second expanded configuration. The insertion instrument can include a tension assembly that applies the predetermined tensile force to the at least one actuation member. The predetermined tensile force can be defined by a distance of travel, a predetermined failure force of a fuse, or a combination of distance of travel and a predetermined failure force of a fuse.

Abstract: Nerve cuff deployment apparatuses and methods of using them to deliver a nerve cuff electrode to a target nerve trunk.

Abstract: A food-product handling device includes a sifter unit having a housing defining an open upper side, a mount extending outwardly from the first housing along a first axis, and a lower side opposite the upper side. The sifter unit further has a sifter basket having an interior aligned with and inset within the open upper side. The device further includes a scale assembly having a body defining an upper opening and an opposite lower opening and having an annular weight-sensing unit surrounding the upper opening. The body is positionable on the housing of the sifter unit with the opening in communication with the open upper side of the housing. A hopper is positionable on the weight-sensing unit and defines a lower open end at least partially received within the body when the hopper is positioned on the weight-sensing unit.

Abstract: A modular electrical connector with separately shielded signal conductor pairs. The connector may be assembled from modules, each containing a pair of signal conductors with surrounding partially or fully conductive material. Modules of different sizes may be assembled into wafers, which are then assembled into a connector. Wafers may include lossy material. In some embodiments, shielding members of two mating connectors may each have compliant members along their distal portions, such that, the shielding members engage at points of contact at multiple locations, some of which are adjacent the mating edge of each of the mating shielding members.

Abstract: An electrical connector module with openings in an insulative support selectively positioned to limit dielectric loss in a signal. The connector may include a first and second conductor including first and second sides between first and second edges. An insulative support holds the first conductor adjacent the second conductor and may have at least five pedestal portions, wherein the first pedestal portion contacts the first side of the first conductor, the second pedestal portion contacts the second side of the first conductor, the third pedestal portion contacts the first side of the second conductor, the fourth pedestal portion contacts the second side of the second conductor, and at least a portion of the fifth pedestal portion is disposed between two edges of the first and second conductors. The pedestal portions may have widths less than the widths of the first and second sides of the first and second conductors.

Abstract: A food-product handling device includes a sifter unit having a housing defining an open upper side, a mount extending outwardly from the first housing along a first axis, and a lower side opposite the upper side. The sifter unit further has a sifter basket having an interior aligned with and inset within the open upper side. The device further includes a scale assembly having a body defining an upper opening and an opposite lower opening and having an annular weight-sensing unit surrounding the upper opening. The body is positionable on the housing of the sifter unit with the opening in communication with the open upper side of the housing. A hopper is positionable on the weight-sensing unit and defines a lower open end at least partially received within the body when the hopper is positioned on the weight-sensing unit.

Abstract: A mixing beater for a stand mixer includes a collar configured to removably couple the mixing beater with the stand mixer. A frame is coupled with the collar and includes a pair of opposing first and second arms. The first and second arms are coupled at their respective distal ends by a frame tip. A central axis of the mixing beater extends through the frame tip, between the opposing first and second arms. A plurality of ribs extends between the first and second arms. Each rib has a rib central axis that extends orthogonal to the central axis of the mixing beater and each of the plurality of ribs is spaced from an adjacent rib to define a space between adjacent ribs.

Abstract: A food-product handling device includes a sifter unit having a housing defining an open upper side, a mount extending outwardly from the first housing along a first axis, and a lower side opposite the upper side. The sifter unit further has a sifter basket having an interior aligned with and inset within the open upper side. The device further includes a scale assembly having a body defining an upper opening and an opposite lower opening and having an annular weight-sensing unit surrounding the upper opening. The body is positionable on the housing of the sifter unit with the opening in communication with the open upper side of the housing. A hopper is positionable on the weight-sensing unit and defines a lower open end at least partially received within the body when the hopper is positioned on the weight-sensing unit.

Abstract: A food processing container includes a food processing chamber and a cover assembly with a latch mechanism operable between latched and unlatched positions. The latch mechanism includes a first magnetic member disposed therein. An interlock assembly is disposed outside of and adjacent to the food processing chamber and includes a sealed cavity with a plunger member moveable disposed within the sealed cavity. The plunger is operable between at-rest and actuated positions within the sealed cavity and includes upper and lower magnetic members disposed at opposite ends of the plunger member. The plunger member moves to the actuated position as the latch mechanism moves to the latched position due to a repulsion force between the first magnetic member and the upper magnetic member, and further wherein the lower magnetic member moves into the lower portion of the sealed cavity as the latch mechanism moves to the latched position.

Abstract: Nerve cuff deployment apparatuses and methods of using them to deliver a nerve cuff electrode to a target nerve trunk.

Abstract: Nerve cuff deployment apparatuses and methods of using them to deliver a nerve cuff electrode to a target nerve trunk.

Abstract: An electrical connector module with openings in an insulative support selectively positioned to limit dielectric loss in a signal. The connector may include a first and second conductor including first and second sides between first and second edges. An insulative support holds the first conductor adjacent the second conductor and may have at least five pedestal portions, wherein the first pedestal portion contacts the first side of the first conductor, the second pedestal portion contacts the second side of the first conductor, the third pedestal portion contacts the first side of the second conductor, the fourth pedestal portion contacts the second side of the second conductor, and at least a portion of the fifth pedestal portion is disposed between two edges of the first and second conductors. The pedestal portions may have widths less than the widths of the first and second sides of the first and second conductors.

Abstract: A modular electrical connector with separately shielded signal conductor pairs. The connector may be assembled from modules, each containing a pair of signal conductors with surrounding partially or fully conductive material. Modules of different sizes may be assembled into wafers, which are then assembled into a connector. Wafers may include lossy material. In some embodiments, shielding members of two mating connectors may each have compliant members along their distal portions, such that, the shielding members engage at points of contact at multiple locations, some of which are adjacent the mating edge of each of the mating shielding members.