Abstract: In one embodiment, a lidar system includes a light source configured to emit local-oscillator (LO) light and pulses of light, the emitted pulses of light including a first emitted pulse of light, where an optical frequency of the first emitted pulse of light is offset from an optical frequency of the LO light by a first frequency offset. The lidar system further includes a receiver configured to detect the LO light and a first received pulse of light, the first received pulse of light including light from the first emitted pulse of light scattered by a target located a distance from the lidar system. The receiver includes a detector, where: the LO light and the first received pulse of light are coherently mixed together at the detector, and the detector is configured to produce a photocurrent signal corresponding to the coherent mixing.

Abstract: The disclosure provides methods, including automated methods, to detect levels of polyanions such as polyvinyl sulfonates in fluids such as buffers by complexometric or titration-based techniques. Such polyanionic compounds have been shown to inhibit enzymes involved in PCR that confounds efforts to monitor the purity of proteins obtained from cell culture, such as biologies and biosimilars.

Abstract: Configurable handheld biological analyzers and related biological analytics methods are described for identification of biological products based on Raman spectroscopy. A biological classification model configuration is loaded into a computer memory of a configurable handheld biological analyzer having a processor and a scanner. The biological classification model configuration includes a biological classification model configured to receive a Raman-based spectra dataset defining a biological product sample as scanned by the scanner. A spectral preprocessing algorithm is executed to reduce a spectral variance of the Raman-based spectra dataset. The biological classification model identifies a biological product type based on the Raman-based spectra dataset and further based on a classification component selected to reduce at least one of (1) a Q-residual error or (2) a summary-of-fit value of the biological classification model.

Abstract: This invention discloses a design a capillary column for use with electrochemically modulated liquid chromatography (EMLC). The capillary design, which results in a marked reduction in the flow of current through the column, enables the use of a two-electrode column construction that overcomes the mechanical and electrical shortfalls of the conventional standard bore design.

Abstract: This invention discloses an approach regarding the use of solid-phase microextractions (SPMEs) in the analytical, bioanalytical, combinatorial sciences, and all other applicable areas of measurement science. The approach applies to the analysis of exceedingly small volumes of a liquid specimen (10s-100s of ?L), and how the concepts of negligible depletion (ND) can be used within the context of tradeoff between extractive (reaction) kinetics, extractive capacity, and sample flow rate as a means to obviate the need to deliver accurately a small volume sample for SPME analysis, improving the ease-of-use for a number of different SPME-based measurements including, for example, disease markers in immunoassays for health care.

Abstract: A remote control with locking mechanism comprising a housing, where the housing includes a front face and a back face; a plurality of buttons on the front face of the housing, where the plurality of buttons operate a plurality of functions on the remote control; and a remote control lock on the housing, where the remote control lock inactivates the plurality of buttons. The remote control lock is positioned on the back face of the housing to prevent accidental pressing. The remote control lock includes an LED light to indicate when the remote control lock is in operation.

Abstract: To prevent display screen burn-in of a picture having, for example, bright lines or other picture components remaining stationary for a long period of time, a video circuit is examined to detect how long the information has not been changed. If a predetermined time limit is exceeded, the picture brightness is limited to a sufficiently low average value or, if so desired, to zero brightness, by means of one or more protection switches.

Abstract: A dynamic audio-video interconnection system for connecting together at least one television receiver and a plurality of peripheral units in home audio-visual installations. By means of a remote-control keyboard, the user transmits interconnection orders which are processed by a microprocessor in order to actuate electronic switches which effect the desired interconnection.