Patents by Inventor Joseph T. Bruder

Joseph T. Bruder has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chimeric adenoviral fiber protein and methods of using same
    Patent number: 5770442
    Abstract: A recombinant adenovirus comprising a chimeric fiber protein and a therapeutic gene, a method of gene therapy involving the use of such an adenovirus, and an adenoviral transfer vector for the generation of such a recombinant adenovirus are provided.
    Type: Grant
    Filed: February 21, 1995
    Date of Patent: June 23, 1998
    Assignees: Cornell Research Foundation, Inc., GenVec, Inc.
    Inventors: Thomas J. Wickham, Erik Falck-Pedersen, Petrus W. Roelvink, Joseph T. Bruder, Jason Gall, Imre Kovesdi
  • Penton base protein and methods of using same
    Patent number: 5731190
    Abstract: A recombinant adenovirus comprising a chimeric penton base protein, which includes a nonpenton base sequence, and a therapeutic gene, a method of gene therapy involving the use of such adenovirus, and adenoviral transfer vectors for the generation of such recombinant adenovirus are provided.
    Type: Grant
    Filed: September 6, 1996
    Date of Patent: March 24, 1998
    Assignee: GenVec, Inc.
    Inventors: Thomas J. Wickham, Imre Kovesdi, Douglas E. Brough, Duncan L. McVey, Joseph T. Bruder
  • Adenoviral-mediated cell targeting commanded by the adenovirus penton base protein
    Patent number: 5712136
    Abstract: A method of introducing an adenovirus into a cell that comprises a particular cell surface binding site, as well as a chimeric adenovirus penton base protein and recombinant adenoviral vector comprising the chimeric adenovirus penton base protein for use in the method, are provided.
    Type: Grant
    Filed: April 17, 1996
    Date of Patent: January 27, 1998
    Assignee: GenVec, Inc.
    Inventors: Thomas J. Wickham, Imre Kovesdi, Petrus W. Roelvink, Douglas E. Brough, Duncan L. McVey, Joseph T. Bruder