Patents by Inventor Joseph T. Roland

Joseph T. Roland has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR TARGETING THE INTERACTION OF HOST MYO5B+D AND CORONAVIRUS M PROTEINS
    Publication number: 20240000885
    Abstract: Disclosed herein is a method for treating or preventing a coronavirus infection in a subject that involves administering to the subject an effective amount of a composition comprising an agent that disrupts the binding of coronavirus membrane glycoprotein (M protein) and Myosin Vb protein (MYO5B). Also disclosed herein is a method for identifying an agent for treating or preventing a coronavirus infection that involves providing a system comprising coronavirus membrane glycoprotein (M protein) and human Myosin Vb protein (MYO5B) with conditions suitable for binding of the M protein and MYO5B; contacting the system with a candidate agent; and assaying the system for binding of M protein and MYO5B.
    Type: Application
    Filed: November 3, 2021
    Publication date: January 4, 2024
    Inventors: Frédéric TANGY, Pierre-Olivier VIDALAIN, James R. GOLDENRING, Joseph T. Roland, Lynne A. LAPIERRE, Elizabeth MANNING, Cornelis Alexander Maria DE HAAN