Patents by Inventor Joseph T. Trotter

Joseph T. Trotter has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230393048
    Abstract: Disclosed herein include systems, devices, and methods for determining a gating strategy. An acquisition system can cause a particle analyzer to collect parameter measurements of some particles of a sample. An analysis system can receive the parameter measurements and determine a gating strategy from the parameter measurements. The acquisition can collect measurements of some or all of the remaining particles of the sample using the gating strategy determined by the analysis system.
    Type: Application
    Filed: August 21, 2023
    Publication date: December 7, 2023
    Inventors: Joseph T. Trotter, Allison Irvine, Nikolay Samusik
  • Patent number: 11788946
    Abstract: Disclosed herein include systems, devices, and methods for determining a gating strategy. An acquisition system can cause a particle analyzer to collect parameter measurements of some particles of a sample. An analysis system can receive the parameter measurements and determine a gating strategy from the parameter measurements. The acquisition can collect measurements of some or all of the remaining particles of the sample using the gating strategy determined by the analysis system.
    Type: Grant
    Filed: October 21, 2022
    Date of Patent: October 17, 2023
    Assignee: BECTON, DICKINSON AND COMPANY
    Inventors: Joseph T. Trotter, Allison Irvine, Nikolay Samusik
  • Publication number: 20230243736
    Abstract: A cell sorting system that automatically generates a sorting strategy based on examples of target events provided by an operator. The target events can be selected using measurements ranging from traditional flow cytometry measurements to derived measurements that are computationally expensive to complex measurements such as images.
    Type: Application
    Filed: April 4, 2023
    Publication date: August 3, 2023
    Inventors: Jonathan Lin, Joseph T. Trotter, Keegan Owsley
  • Publication number: 20230043744
    Abstract: Disclosed herein include systems, devices, and methods for determining a gating strategy. An acquisition system can cause a particle analyzer to collect parameter measurements of some particles of a sample. An analysis system can receive the parameter measurements and determine a gating strategy from the parameter measurements. The acquisition can collect measurements of some or all of the remaining particles of the sample using the gating strategy determined by the analysis system.
    Type: Application
    Filed: October 21, 2022
    Publication date: February 9, 2023
    Inventors: Joseph T. Trotter, Allison Irvine, Nikolay Samusik
  • Patent number: 11513054
    Abstract: Disclosed herein include systems, devices, and methods for determining a gating strategy. An acquisition system can cause a particle analyzer to collect parameter measurements of some particles of a sample. An analysis system can receive the parameter measurements and determine a gating strategy from the parameter measurements. The acquisition can collect measurements of some or all of the remaining particles of the sample using the gating strategy determined by the analysis system.
    Type: Grant
    Filed: January 10, 2020
    Date of Patent: November 29, 2022
    Assignee: Becton, Dickinson and Company
    Inventors: Joseph T. Trotter, Allison Irvine, Nikolay Samusik
  • Publication number: 20220155209
    Abstract: Aspects of the present disclosure include methods for processing and scaling cytometric data. Methods according to certain embodiments include obtaining cytometric data for a sample, wherein the cytometric data comprises measurements of a plurality of parameters from particles irradiated in the sample flowing in a flow stream; identifying a parameter of interest; specifying positive and negative measurement intervals on the parameter of interest; scaling the cytometric data by transforming the parameter of interest based at least in part on the corresponding specified positive and negative intervals. Systems for practicing the subject methods are also provided. Non-transitory computer readable storage mediums are also described.
    Type: Application
    Filed: September 9, 2021
    Publication date: May 19, 2022
    Inventors: Nikolay Samusik, Joseph T. Trotter
  • Publication number: 20210278333
    Abstract: Methods for adjusting a training gate prepared from a first set of flow cytometer data to accommodate a second set of flow cytometer data are provided. In embodiments, methods include generating an image for each of the first and second sets of flow cytometer data. In some instances, generating an image includes organizing the data into two-dimensional bins, and assigning shades to each bin such that the bins are represented by pixels. In some instances, methods include warping with a computer implemented algorithm the generated image of the first set of flow cytometer data such that it maximizes resemblance to the second set of flow cytometer data, and applying the same transformation to the training gate. In some embodiments, methods include overlaying the adjusted training gate onto the generated image of the second set of flow cytometer data. Systems and computer-readable media for adjusting a training gate are also provided.
    Type: Application
    Filed: January 21, 2021
    Publication date: September 9, 2021
    Inventors: Allison Irvine, Nikolay Samusik, Joseph T. Trotter
  • Publication number: 20200225141
    Abstract: Disclosed herein include systems, devices, and methods for determining a gating strategy. An acquisition system can cause a particle analyzer to collect parameter measurements of some particles of a sample. An analysis system can receive the parameter measurements and determine a gating strategy from the parameter measurements. The acquisition can collect measurements of some or all of the remaining particles of the sample using the gating strategy determined by the analysis system.
    Type: Application
    Filed: January 10, 2020
    Publication date: July 16, 2020
    Inventors: Joseph T. Trotter, Allison Irvine, Nikolay Samusik
  • Patent number: 9835540
    Abstract: Devices for sorting components (e.g., cells) contained in a liquid sample are provided. In certain aspects, the devices include a magnetic separation device and an acoustic concentrator device fluidically coupled to magnetic separation device. Aspects of the invention further include methods for sorting cells in a liquid sample, and systems, and kits for practicing the subject methods.
    Type: Grant
    Filed: May 13, 2016
    Date of Patent: December 5, 2017
    Assignee: Becton, Dickinson and Company
    Inventors: Liping Yu, Brian David Warner, Joseph T. Trotter
  • Patent number: 9513205
    Abstract: Devices for sorting components (e.g., cells) contained in a liquid sample are provided. In certain aspects, the devices include a magnetic separation device and an acoustic concentrator device fluidically coupled to magnetic separation device. Aspects of the invention further include methods for sorting cells in a liquid sample, and systems, and kits for practicing the subject methods.
    Type: Grant
    Filed: January 6, 2015
    Date of Patent: December 6, 2016
    Assignee: Becton, Dickinson and Company
    Inventors: Liping Yu, Brian David Warner, Joseph T. Trotter
  • Publication number: 20160252445
    Abstract: Devices for sorting components (e.g., cells) contained in a liquid sample are provided. In certain aspects, the devices include a magnetic separation device and an acoustic concentrator device fluidically coupled to magnetic separation device. Aspects of the invention further include methods for sorting cells in a liquid sample, and systems, and kits for practicing the subject methods.
    Type: Application
    Filed: May 13, 2016
    Publication date: September 1, 2016
    Inventors: Liping Yu, Brian David Warner, Joseph T. Trotter
  • Publication number: 20150160116
    Abstract: Devices for sorting components (e.g., cells) contained in a liquid sample are provided. In certain aspects, the devices include a magnetic separation device and an acoustic concentrator device fluidically coupled to magnetic separation device. Aspects of the invention further include methods for sorting cells in a liquid sample, and systems, and kits for practicing the subject methods.
    Type: Application
    Filed: January 6, 2015
    Publication date: June 11, 2015
    Inventors: Liping Yu, Brian David Warner, Joseph T. Trotter
  • Patent number: 8956536
    Abstract: Devices for sorting components (e.g., cells) contained in a liquid sample are provided. In certain aspects, the devices include a magnetic separation device and an acoustic concentrator device fluidically coupled to magnetic separation device. Aspects of the invention further include methods for sorting cells in a liquid sample, and systems, and kits for practicing the subject methods.
    Type: Grant
    Filed: October 23, 2013
    Date of Patent: February 17, 2015
    Assignee: Becton, Dickinson and Company
    Inventors: Liping Yu, Brian David Warner, Joseph T. Trotter
  • Patent number: 8865470
    Abstract: The present invention reagents and methods for setting up an instruments having a multiplicity of detector channels for analyzing a multiplicity of fluorescent dyes. The present invention is particularly applicable in the field of flow cytometry.
    Type: Grant
    Filed: March 6, 2013
    Date of Patent: October 21, 2014
    Assignee: Becton, Dickinson and Company
    Inventors: Ming Yan, Alan M. Stall, Joseph T. Trotter, Robert A. Hoffman
  • Publication number: 20140120570
    Abstract: Devices for sorting components (e.g., cells) contained in a liquid sample are provided. In certain aspects, the devices include a magnetic separation device and an acoustic concentrator device fluidically coupled to magnetic separation device. Aspects of the invention further include methods for sorting cells in a liquid sample, and systems, and kits for practicing the subject methods.
    Type: Application
    Filed: October 23, 2013
    Publication date: May 1, 2014
    Inventors: Liping Yu, Brian David Warner, Joseph T. Trotter
  • Publication number: 20140110297
    Abstract: This invention relates to methods for evaluating or inhibiting the aggregation of a protein in an aqueous suspension including organopolysiloxane and medical articles coated with organopolysiloxane containing a protein solution including sugar and non-ionic surfactant.
    Type: Application
    Filed: December 23, 2013
    Publication date: April 24, 2014
    Applicants: THE REGENTS OF THE UNIVERSITY OF COLORADO, BECTON, DICKINSON AND COMPANY
    Inventors: Joseph T. Trotter, Jean-Bernard Hamel, John Frank Carpenter, Theodore Randolph, John Paul Gabrielson
  • Publication number: 20140087394
    Abstract: The present invention reagents and methods for setting up an instruments having a multiplicity of detector channels for analyzing a multiplicity of fluorescent dyes. The present invention is particularly applicable in the field of flow cytometry.
    Type: Application
    Filed: March 6, 2013
    Publication date: March 27, 2014
    Inventors: Ming Yan, Alan M. Stall, Joseph T. Trotter, Robert A. Hoffman
  • Patent number: 8633034
    Abstract: This invention relates to methods for evaluating or inhibiting the aggregation of a protein in an aqueous suspension including organopolysiloxane and medical articles coated with organopolysiloxane containing a protein solution including sugar and a non-ionic surfactant.
    Type: Grant
    Filed: October 22, 2008
    Date of Patent: January 21, 2014
    Assignees: Becton, Dickinson and Company, The Regents of the University of Colorado
    Inventors: Joseph T. Trotter, Jean-Bernard Hamel, John Frank Carpenter, Theodore Randolph, John Paul Gabrielson
  • Patent number: 8415161
    Abstract: The present invention reagents and methods for setting up an instruments having a multiplicity of detector channels for analyzing a multiplicity of fluorescent dyes. The present invention is particularly applicable in the field of flow cytometry.
    Type: Grant
    Filed: November 10, 2009
    Date of Patent: April 9, 2013
    Assignee: Becton, Dickinson and Company
    Inventors: Ming Yan, Alan M. Stall, Joseph T. Trotter, Robert A. Hoffman
  • Publication number: 20110106044
    Abstract: This invention relates to methods for evaluating or inhibiting the aggregation of a protein in an aqueous suspension including organopolysiloxane and medical articles coated with organopolysiloxane containing a protein solution including sugar and a non-ionic surfactant.
    Type: Application
    Filed: October 22, 2008
    Publication date: May 5, 2011
    Applicants: BECTON, DICKINSON AND COMPANY, THE REGENTS OF THE UNIVERSITY OF COLORADO
    Inventors: Joseph T. Trotter, Jean-Bernard Hamel, John Frank Carpenter, Theodore Randolph, John Paul Gabrielson