Patents by Inventor Joseph Traina
Joseph Traina has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 11571498Abstract: The present disclosure relates to medical devices, and methods for producing and using the devices. In embodiments, the medical device may be a buttress including a porous substrate possessing a therapeutic layer of a chemotherapeutic agent and optional excipient(s) thereon. By varying the form of chemotherapeutic agents and excipients, the medical devices may be used to treat both the area to which the medical device is attached as well as tissue at a distance therefrom.Type: GrantFiled: November 30, 2020Date of Patent: February 7, 2023Assignee: Covidien LPInventors: Terry Morgan, Beth Sersen, Daniel Schulz-Jander, Joseph Traina, Brian Graham, Carol Sullivan, Gerald Hodgkinson
-
Publication number: 20210085831Abstract: The present disclosure relates to medical devices, and methods for producing and using the devices. In embodiments, the medical device may be a buttress including a porous substrate possessing a therapeutic layer of a chemotherapeutic agent and optional excipient(s) thereon. By varying the form of chemotherapeutic agents and excipients, the medical devices may be used to treat both the area to which the medical device is attached as well as tissue at a distance therefrom.Type: ApplicationFiled: November 30, 2020Publication date: March 25, 2021Inventors: Terry Morgan, Beth Sersen, Daniel Schulz-Jander, Joseph Traina, Brian Graham, Carol Sullivan, Gerald Hodgkinson
-
Patent number: 10874768Abstract: The present disclosure relates to medical devices, and methods for producing and using the devices. In embodiments, the medical device may be a buttress including a porous substrate possessing a therapeutic layer of a chemotherapeutic agent and optional excipient(s) thereon. By varying the form of chemotherapeutic agents and excipients, the medical devices may be used to treat both the area to which the medical device is attached as well as tissue at a distance therefrom.Type: GrantFiled: December 11, 2017Date of Patent: December 29, 2020Assignee: COVIDIEN LPInventors: Terry Morgan, Beth Sersen, Daniel Schulz-Jander, Joseph Traina, Brian Graham, Carol Sullivan, Gerald Hodgkinson
-
Publication number: 20180207321Abstract: The present disclosure relates to medical devices, and methods for producing and using the devices. In embodiments, the medical device may be a buttress including a porous substrate possessing a therapeutic layer of a chemotherapeutic agent and optional excipient(s) thereon. By varying the form of chemotherapeutic agents and excipients, the medical devices may be used to treat both the area to which the medical device is attached as well as tissue at a distance therefrom.Type: ApplicationFiled: December 11, 2017Publication date: July 26, 2018Inventors: Terry Morgan, Beth Sersen, Daniel Schulz-Jander, Joseph Traina, Brian Graham, Carol Sullivan, Gerald Hodgkinson
-
Patent number: 9867722Abstract: Methods and apparatus are disclosed for filling a therapeutic substance or drug within a hollow wire that forms a stent. The stent is placed within a chamber housing a fluid drug formulation. During filling, the chamber is maintained at or near the vapor-liquid equilibrium of the solvent of the fluid drug formulation. To fill the stent, a portion of the stent is placed into contact with the fluid drug formulation until a lumenal space defined by the hollow wire is filled with the fluid drug formulation via capillary action. After filling is complete, the stent is retracted such that the stent is no longer in contact with the fluid drug formulation. The solvent vapor pressure within the chamber is reduced to evaporate a solvent of the fluid drug formulation. A wicking means may control transfer of the fluid drug formulation into the stent.Type: GrantFiled: October 29, 2015Date of Patent: January 16, 2018Assignee: Medtronic Vascular, Inc.Inventors: Justin Peterson, James Mitchell, Abby Schlichting, Nathanael Glucklich, Joseph Traina, Rajen Kumar
-
Publication number: 20160120666Abstract: Methods and apparatus are disclosed for filling a therapeutic substance or drug within a hollow wire that forms a stent. The stent is placed within a chamber housing a fluid drug formulation. During filling, the chamber is maintained at or near the vapor-liquid equilibrium of the solvent of the fluid drug formulation. To fill the stent, a portion of the stent is placed into contact with the fluid drug formulation until a lumenal space defined by the hollow wire is filled with the fluid drug formulation via capillary action. After filling is complete, the stent is retracted such that the stent is no longer in contact with the fluid drug formulation. The solvent vapor pressure within the chamber is reduced to evaporate a solvent of the fluid drug formulation. A wicking means may control transfer of the fluid drug formulation into the stent.Type: ApplicationFiled: October 29, 2015Publication date: May 5, 2016Inventors: Justin Peterson, James Mitchell, Abby Schlichting, Nathanael Glucklich, Joseph Traina, Rajen Kumar
-
Patent number: 8828474Abstract: Methods and apparatus are disclosed for loading a therapeutic substance or drug within a lumenal space of a hollow wire having a plurality of side openings along a length thereof that forms a hollow drug-eluting stent with a plurality of side drug delivery openings. Loading a drug within the lumenal space of the hollow stent includes a drug filling step, in which the drug is mixed with a solvent or dispersion medium. The lumenal space may be filled with the drug solution or suspension in a reverse fill process and/or a forward fill process. After the drug filling step, a solvent or dispersion medium extracting step is performed to extract the solvent or dispersion medium from within the lumenal space such that only the drug remains within the hollow stent. A stent cleaning step may be performed to an exterior surface of the hollow stent.Type: GrantFiled: September 17, 2010Date of Patent: September 9, 2014Assignee: Medtronic Vascular, Inc.Inventors: James E. Mitchell, William Heaton, Dishuan Chu, Terry Morgan, Justin Peterson, Joseph Traina
-
Patent number: 8460745Abstract: Methods and apparatus are disclosed for loading a therapeutic substance or drug within a lumenal space of a hollow wire having a plurality of side openings along a length thereof that forms a hollow drug-eluting stent with a plurality of side drug delivery openings. Loading a drug within the lumenal space of the hollow stent includes a drug filling step, in which the drug is mixed with a solvent or dispersion medium. The lumenal space may be filled with the drug solution or suspension in a reverse fill process and/or a forward fill process. After the drug filling step, a solvent or dispersion medium extracting step is performed to extract the solvent or dispersion medium from within the lumenal space such that only the drug remains within the hollow stent. A stent cleaning step may be performed to an exterior surface of the hollow stent.Type: GrantFiled: September 17, 2010Date of Patent: June 11, 2013Assignee: Medtronic Vascular, Inc.Inventors: James Mitchell, Justin Peterson, Dishuan Chu, Joseph Traina, Salvador Avelar, Michele Silver
-
Patent number: 8381774Abstract: Methods and apparatus are disclosed for loading a therapeutic substance or drug within a lumenal space of a hollow wire having a plurality of side openings along a length thereof that forms a hollow drug-eluting stent with a plurality of side drug delivery openings. Loading a drug within the lumenal space of the hollow stent includes a drug filling step, in which the drug is mixed with a solvent or dispersion medium. The lumenal space may be filled with the drug solution or suspension in a reverse fill process and/or a forward fill process. After the drug filling step, a solvent or dispersion medium extracting step is performed to extract the solvent or dispersion medium from within the lumenal space such that only the drug remains within the hollow stent. A stent cleaning step may be performed to an exterior surface of the hollow stent.Type: GrantFiled: September 17, 2010Date of Patent: February 26, 2013Assignee: Medtronic Vascular, Inc.Inventors: James Mitchell, Dishuan Chu, Justin Peterson, Joseph Traina
-
Publication number: 20120259314Abstract: A method of recanalizing a chronic total occlusion (CTO) is disclosed. A catheter with a guidewire slidingly received therein is positioned proximally adjacent to the CTO. An occlusion weakening therapy effective to quickly soften and/or loosen the CTO is delivered to the CTO via the catheter. The occlusion weakening therapy includes at least one enzyme and a chelating agent which are selectively deliverable either together or separately depending on the type of material encountered by the guidewire. According to various methods, the enzyme(s) may be delivered if tissue is encountered, the chelating agent may be delivered if calcification is encountered, and both enzyme(s) and chelating agent(s) may be delivered if a fibrous cap is encountered. The distal end of the guidewire may be advanced into the CTO shortly after delivery of the occlusion weakening therapy and is manipulated through the CTO until the guidewire successfully crosses the CTO.Type: ApplicationFiled: April 11, 2011Publication date: October 11, 2012Applicant: Medtronic Vascular, Inc.Inventors: Ya Guo, Stefan Tunev, Joseph Traina
-
Publication number: 20120070563Abstract: Methods and apparatus are disclosed for loading a therapeutic substance or drug within a lumenal space of a hollow wire having a plurality of side openings along a length thereof that forms a hollow drug-eluting stent with a plurality of side drug delivery openings. Loading a drug within the lumenal space of the hollow stent includes a drug filling step, in which the drug is mixed with a solvent or dispersion medium. The lumenal space may be filled with the drug solution or suspension in a reverse fill process and/or a forward fill process. After the drug filling step, a solvent or dispersion medium extracting step is performed to extract the solvent or dispersion medium from within the lumenal space such that only the drug remains within the hollow stent. A stent cleaning step may be performed to an exterior surface of the hollow stent.Type: ApplicationFiled: September 17, 2010Publication date: March 22, 2012Applicant: Medtronic Vascular, Inc.Inventors: James E. Mitchell, William Heaton, Dishuan Chu, Terry Morgan, Justin Peterson, Joseph Traina
-
Publication number: 20110067778Abstract: Methods and apparatus are disclosed for loading a therapeutic substance or drug within a lumenal space of a hollow wire having a plurality of side openings along a length thereof that forms a hollow drug-eluting stent with a plurality of side drug delivery openings. Loading a drug within the lumenal space of the hollow stent includes a drug filling step, in which the drug is mixed with a solvent or dispersion medium. The lumenal space may be filled with the drug solution or suspension in a reverse fill process and/or a forward fill process. After the drug filling step, a solvent or dispersion medium extracting step is performed to extract the solvent or dispersion medium from within the lumenal space such that only the drug remains within the hollow stent. A stent cleaning step may be performed to an exterior surface of the hollow stent.Type: ApplicationFiled: September 17, 2010Publication date: March 24, 2011Applicant: Medtronic Vascular, Inc.Inventors: James E. Mitchell, Dishuan Chu, Justin Peterson, Joseph Traina
-
Publication number: 20110070357Abstract: Methods and apparatus are disclosed for loading a therapeutic substance or drug within a lumenal space of a hollow wire having a plurality of side openings along a length thereof that forms a hollow drug-eluting stent with a plurality of side drug delivery openings. Loading a drug within the lumenal space of the hollow stent includes a drug filling step, in which the drug is mixed with a solvent or dispersion medium. The lumenal space may be filled with the drug solution or suspension in a reverse fill process and/or a forward fill process. After the drug filling step, a solvent or dispersion medium extracting step is performed to extract the solvent or dispersion medium from within the lumenal space such that only the drug remains within the hollow stent. A stent cleaning step may be performed to an exterior surface of the hollow stent.Type: ApplicationFiled: September 17, 2010Publication date: March 24, 2011Applicant: Medtronic Vascular, Inc.Inventors: James E. Mitchell, Justin Peterson, Dishuan Chu, Joseph Traina, Salvador Avelar, Michele Silver
-
Patent number: 4087049Abstract: An aboveground sprinkling device for a spinkling system for lawns and gardens. The device has a sprinkler head at the center of its upper surface and has four sockets spaced at ninety-degree intervals around its side edge, all leading in to a central chamber immediately below the sprinkler head. An integral holding spike extends down from the bottom of the sprinkler head, preferably at the center, for holding the sprinkling device in a selected location. The spike is shaped to resist rotation. A set of plugs is provided to close the sockets that are not to be used. A hose or hoses can be secured to any one of the sockets or to several of them or to all of them to incorporate the device in a continuous sprinkler system employing a plurality of these sprinkling devices. The sockets not connected to hoses are plugged.Type: GrantFiled: September 23, 1976Date of Patent: May 2, 1978Inventor: Vincent Joseph Traina