Patents by Inventor Joseph Vockley

Joseph Vockley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190024172
    Abstract: Ancestry has a significant impact on the major and minor alleles found in each nucleotide position within the genome. Due to mechanisms of inheritance, ancestral-specific information contained within the genome is conserved within members of an ancestry. For this reason, individuals within a specific ancestry are more likely to share alleles in their genomes with other members of the same ancestry. Functionally, the combination of alleles at all positions within a group of individuals defines that group as having a common ancestry. Moreover, the aggregation of differences between alleles at all positions distinguishes one ancestry from another. The genomic similarities and differences between ancestries provides a mechanism to generate reference genomes that are specific for each ancestry.
    Type: Application
    Filed: March 9, 2018
    Publication date: January 24, 2019
    Applicant: INOVA HEALTH SYSTEM
    Inventors: Joseph Vockley, John Niederhuber
  • Patent number: 9639659
    Abstract: Ancestry has a significant impact on the major and minor alleles found in each nucleotide position within the genome. Due to mechanisms of inheritance, ancestral-specific information contained within the genome is conserved within members of an ancestry. For this reason, individuals within a specific ancestry are more likely to share alleles in their genomes with other members of the same ancestry. Functionally, the combination of alleles at all positions within a group of individuals defines that group as having a common ancestry. Moreover, the aggregation of differences between alleles at all positions distinguishes one ancestry from another. The genomic similarities and differences between ancestries provides a mechanism to generate reference genomes that are specific for each ancestry.
    Type: Grant
    Filed: August 27, 2016
    Date of Patent: May 2, 2017
    Assignee: INOVA HEALTH SYSTEM
    Inventors: Joseph Vockley, John Niederhuber
  • Patent number: 9639658
    Abstract: Ancestry has a significant impact on the major and minor alleles found in each nucleotide position within the genome. Due to mechanisms of inheritance, ancestral-specific information contained within the genome is conserved within members of an ancestry. For this reason, individuals within a specific ancestry are more likely to share alleles in their genomes with other members of the same ancestry. Functionally, the combination of alleles at all positions within a group of individuals defines that group as having a common ancestry. Moreover, the aggregation of differences between alleles at all positions distinguishes one ancestry from another. The genomic similarities and differences between ancestries provides a mechanism to generate reference genomes that are specific for each ancestry.
    Type: Grant
    Filed: August 27, 2016
    Date of Patent: May 2, 2017
    Assignee: INOVA HEALTH SYSTEM
    Inventors: Joseph Vockley, John Niederhuber
  • Publication number: 20170017756
    Abstract: Ancestry has a significant impact on the major and minor alleles found in each nucleotide position within the genome. Due to mechanisms of inheritance, ancestral-specific information contained within the genome is conserved within members of an ancestry. For this reason, individuals within a specific ancestry are more likely to share alleles in their genomes with other members of the same ancestry. Functionally, the combination of alleles at all positions within a group of individuals defines that group as having a common ancestry. Moreover, the aggregation of differences between alleles at all positions distinguishes one ancestry from another. The genomic similarities and differences between ancestries provides a mechanism to generate reference genomes that are specific for each ancestry.
    Type: Application
    Filed: August 27, 2016
    Publication date: January 19, 2017
    Inventors: Joseph Vockley, John Niederhuber
  • Publication number: 20170017751
    Abstract: Ancestry has a significant impact on the major and minor alleles found in each nucleotide position within the genome. Due to mechanisms of inheritance, ancestral-specific information contained within the genome is conserved within members of an ancestry. For this reason, individuals within a specific ancestry are more likely to share alleles in their genomes with other members of the same ancestry. Functionally, the combination of alleles at all positions within a group of individuals defines that group as having a common ancestry. Moreover, the aggregation of differences between alleles at all positions distinguishes one ancestry from another. The genomic similarities and differences between ancestries provides a mechanism to generate reference genomes that are specific for each ancestry.
    Type: Application
    Filed: August 27, 2016
    Publication date: January 19, 2017
    Inventors: Joseph Vockley, John Niederhuber
  • Publication number: 20170017753
    Abstract: Ancestry has a significant impact on the major and minor alleles found in each nucleotide position within the genome. Due to mechanisms of inheritance, ancestral-specific information contained within the genome is conserved within members of an ancestry. For this reason, individuals within a specific ancestry are more likely to share alleles in their genomes with other members of the same ancestry. Functionally, the combination of alleles at all positions within a group of individuals defines that group as having a common ancestry. Moreover, the aggregation of differences between alleles at all positions distinguishes one ancestry from another. The genomic similarities and differences between ancestries provides a mechanism to generate reference genomes that are specific for each ancestry.
    Type: Application
    Filed: August 27, 2016
    Publication date: January 19, 2017
    Inventors: Joseph Vockley, John Niederhuber
  • Publication number: 20170017754
    Abstract: Ancestry has a significant impact on the major and minor alleles found in each nucleotide position within the genome. Due to mechanisms of inheritance, ancestral-specific information contained within the genome is conserved within members of an ancestry. For this reason, individuals within a specific ancestry are more likely to share alleles in their genomes with other members of the same ancestry. Functionally, the combination of alleles at all positions within a group of individuals defines that group as having a common ancestry. Moreover, the aggregation of differences between alleles at all positions distinguishes one ancestry from another. The genomic similarities and differences between ancestries provides a mechanism to generate reference genomes that are specific for each ancestry.
    Type: Application
    Filed: August 27, 2016
    Publication date: January 19, 2017
    Inventors: Joseph Vockley, John Niederhuber
  • Publication number: 20170017755
    Abstract: Ancestry has a significant impact on the major and minor alleles found in each nucleotide position within the genome. Due to mechanisms of inheritance, ancestral-specific information contained within the genome is conserved within members of an ancestry. For this reason, individuals within a specific ancestry are more likely to share alleles in their genomes with other members of the same ancestry. Functionally, the combination of alleles at all positions within a group of individuals defines that group as having a common ancestry. Moreover, the aggregation of differences between alleles at all positions distinguishes one ancestry from another. The genomic similarities and differences between ancestries provides a mechanism to generate reference genomes that are specific for each ancestry.
    Type: Application
    Filed: August 27, 2016
    Publication date: January 19, 2017
    Inventors: Joseph Vockley, John Niederhuber
  • Publication number: 20170017757
    Abstract: Ancestry has a significant impact on the major and minor alleles found in each nucleotide position within the genome. Due to mechanisms of inheritance, ancestral-specific information contained within the genome is conserved within members of an ancestry. For this reason, individuals within a specific ancestry are more likely to share alleles in their genomes with other members of the same ancestry. Functionally, the combination of alleles at all positions within a group of individuals defines that group as having a common ancestry. Moreover, the aggregation of differences between alleles at all positions distinguishes one ancestry from another. The genomic similarities and differences between ancestries provides a mechanism to generate reference genomes that are specific for each ancestry.
    Type: Application
    Filed: August 27, 2016
    Publication date: January 19, 2017
    Inventors: Joseph Vockley, John Niederhuber
  • Publication number: 20170011168
    Abstract: Ancestry has a significant impact on the major and minor alleles found in each nucleotide position within the genome. Due to mechanisms of inheritance, ancestral-specific information contained within the genome is conserved within members of an ancestry. For this reason, individuals within a specific ancestry are more likely to share alleles in their genomes with other members of the same ancestry. Functionally, the combination of alleles at all positions within a group of individuals defines that group as having a common ancestry. Moreover, the aggregation of differences between alleles at all positions distinguishes one ancestry from another. The genomic similarities and differences between ancestries provides a mechanism to generate reference genomes that are specific for each ancestry.
    Type: Application
    Filed: August 27, 2016
    Publication date: January 12, 2017
    Inventors: Joseph Vockley, John Niederhuber
  • Publication number: 20170009292
    Abstract: Ancestry has a significant impact on the major and minor alleles found in each nucleotide position within the genome. Due to mechanisms of inheritance, ancestral-specific information contained within the genome is conserved within members of an ancestry. For this reason, individuals within a specific ancestry are more likely to share alleles in their genomes with other members of the same ancestry. Functionally, the combination of alleles at all positions within a group of individuals defines that group as having a common ancestry. Moreover, the aggregation of differences between alleles at all positions distinguishes one ancestry from another. The genomic similarities and differences between ancestries provides a mechanism to generate reference genomes that are specific for each ancestry.
    Type: Application
    Filed: September 23, 2016
    Publication date: January 12, 2017
    Inventors: Joseph Vockley, John Niederhuber
  • Patent number: 9449143
    Abstract: Ancestry has a significant impact on the major and minor alleles found in each nucleotide position within the genome. Due to mechanisms of inheritance, ancestral-specific information contained within the genome is conserved within members of an ancestry. For this reason, individuals within a specific ancestry are more likely to share alleles in their genomes with other members of the same ancestry. Functionally, the combination of alleles at all positions within a group of individuals defines that group as having a common ancestry. Moreover, the aggregation of differences between alleles at all positions distinguishes one ancestry from another. The genomic similarities and differences between ancestries provides a mechanism to generate reference genomes that are specific for each ancestry.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: September 20, 2016
    Assignee: INOVA HEALTH SYSTEM
    Inventors: Joseph Vockley, John Niederhuber
  • Publication number: 20140067280
    Abstract: Ancestry has a significant impact on the major and minor alleles found in each nucleotide position within the genome. Due to mechanisms of inheritance, ancestral-specific information contained within the genome is conserved within members of an ancestry. For this reason, individuals within a specific ancestry are more likely to share alleles in their genomes with other members of the same ancestry. Functionally, the combination of alleles at all positions within a group of individuals defines that group as having a common ancestry. Moreover, the aggregation of differences between alleles at all positions distinguishes one ancestry from another. The genomic similarities and differences between ancestries provides a mechanism to generate reference genomes that are specific for each ancestry.
    Type: Application
    Filed: March 15, 2013
    Publication date: March 6, 2014
    Inventors: Joseph Vockley, John Niederhuber
  • Patent number: 6974667
    Abstract: The present invention identifies the global changes in gene expression associated with liver cancer by examining gene expression in tissue from normal liver, metastatic malignant liver and hepatocellular carcinoma. The present invention also identifies expression profiles which serve as useful diagnostic markers as well as markers that can be used to monitor disease states, disease progression, drug toxicity, drug efficacy and drug metabolism.
    Type: Grant
    Filed: June 14, 2001
    Date of Patent: December 13, 2005
    Assignee: Gene Logic, Inc.
    Inventors: Darci T. Horne, Uwe Scherf, Joseph Vockley
  • Publication number: 20050050101
    Abstract: Identifying genomic sequences and oligonucleotide sequences unique to a set of organisms. Methods include obtaining genomic data characteristic of the set; formatting the data into at least one query-length sequence, each query-length sequence being of a format compatible with a similarity search engine. Searching a selected genomic database using the query and the similarity search engine. Then parsing the results of the search for those sequences showing uniqueness to the set.
    Type: Application
    Filed: January 23, 2004
    Publication date: March 3, 2005
    Inventors: Joseph Vockley, Gregory Eley
  • Publication number: 20020142981
    Abstract: The present invention identifies the global changes in gene expression associated with liver cancer by examining gene expression in tissue from normal liver, metastatic malignant liver and hepatocellular carcinoma. The present invention also identifies expression profiles which serve as useful diagnostic markers as well as markers that can be used to monitor disease states, disease progression, drug toxicity, drug efficacy and drug metabolism.
    Type: Application
    Filed: June 14, 2001
    Publication date: October 3, 2002
    Inventors: Darci T. Horne, Uwe Scherf, Joseph Vockley