Patents by Inventor Joseph Walter ARNDT

Joseph Walter ARNDT has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HUMAN-DERIVED ANTI-(POLY-GA) DIPEPTIDE REPEAT (DPR) ANTIBODY
    Publication number: 20220153874
    Abstract: Provided are novel dipeptide repeat (DPR) specific antibodies (e.g., human-derived antibodies) as well as synthetic variants and biotechnological derivatives thereof, capable of binding C9orf72 poly-glycine-alanine DPRs, as well as methods and uses related thereto. The antibody of the present invention can be used in pharmaceutical and diagnostic compositions for DPR protein-targeted immunotherapy and diagnostics.
    Type: Application
    Filed: April 25, 2019
    Publication date: May 19, 2022
    Inventors: Jan Grimm, Fabio Montrasio, Isin Dalkilic-Liddle, Mia Marie Rushe, Joseph Walter Arndt
  • ANTI-VLA-4 ANTIBODIES HAVING REDUCED EFFECTOR FUNCTION
    Publication number: 20210238289
    Abstract: The invention relates to anti-VLA-4 antibodies and binding fragments thereof. The invention further includes polynucleotides encoding said antibodies and binding fragments thereof and methods of manufacturing said antibodies and binding fragments thereof. The invention further includes methods of treating patients suffering from multiple sclerosis and/or epilepsy by administration of said antibodies and binding fragments thereof. The invention further includes methods of reducing the susceptibility to scrambling of a recombinant anti-alpha 4 antibody or a binding fragment thereof.
    Type: Application
    Filed: May 31, 2019
    Publication date: August 5, 2021
    Applicant: BIOGEN MA INC.
    Inventors: Janine Lisa FERRANT-ORGETTAS, Robert Blake PEPINSKY, Ellen Duggan CAHIR-MCFARLAND, Nadia Giselle D'LIMA, Joseph Walter ARNDT, Karl John Mortley HANF, Thomas Owen CAMERON, Ellen Garber STARK