Abstract: The present invention discloses methods, primer, probes, and kits for genotyping various mutations or disease-causing agent. In one embodiment, the present invention is applied to detecting the presence of multidrug-resistant Mycobacterium tuberculosis, HBV, beta-globin mutations, mutations related to thrombophilia, or the presence of sexually transmitted diseases in a subject.

Abstract: The present invention describes methods of performing rapid nucleic acid detection using a flow through process. The methods comprise single-step signal amplification and/or a one-step hybridization protocol. Using the flow through hybridization process, the present invention provides a more efficient, faster and less expensive genotyping method. This invention further provides a Single Nucleotide Polymorphism (SNP)-based DNA fingerprinting method for rapid and accurate genotyping, identification as well as DNA analyses of genetic materials from human beings and other different organisms. In addition this invention also discloses devices for rapid and sensitive analysis of target analysts.

Abstract: The present invention describes methods of performing rapid nucleic acid detection using a flow through process. The methods comprise single-step signal amplification and/or a one-step hybridization protocol. Using the flow through hybridization process, the present invention provides a more efficient, faster and less expensive genotyping method. This invention further provides a Single Nucleotide Polymorphism (SNP)-based DNA fingerprinting method for rapid and accurate genotyping, identification as well as DNA analyses of genetic materials from human beings and other different organisms. In addition this invention also discloses devices for rapid and sensitive analysis of target analysts.

Abstract: The present invention discloses methods and devices for rapid genotyping. In one embodiment, the present invention is applied to human papillomavirus (HPV) genotyping, comprising the use of viral genotype-specific-oligonucleotide probes, reversed-dot-blotting genotype array format and flow through hybridization process, thereby providing a more efficient, faster and less expensive method for HPV genotyping. The genotyping method further comprises the use of generic probes to expand the detection of HPV genotypes.

Abstract: The present invention describes methods of performing rapid nucleic acid detection using a flow through process. The methods comprise single-step signal amplification and/or a one-step hybridization protocol. Using the flow through hybridization process, the present invention provides a more efficient, faster and less expensive genotyping method. This invention further provides a Single Nucleotide Polymorphism (SNP)-based DNA fingerprinting method for rapid and accurate genotyping, identification as well as DNA analyses of genetic materials from human beings and other different organisms. In addition this invention also discloses devices for rapid and sensitive analysis of target analysts.

Abstract: The present invention discloses the use of Allele-Specific-Oligonucleotide (ASO) as a detection assay for human HLA classification. Using Reversed-Dot-Blotting format and flow through hybridization process, more efficient, faster and less expensive HLA classification can be achieved. A simplified procedure for HLA genotyping is also described. This invention further provides a Single Nucleotide Polymorphism (SNP)-based DNA fingerprining method for rapid and accurate genotyping, identification as well as DNA analyses of genetic data from human beings and different organisms. In addition this invention also discloses a new device for rapid and sensitive analyses of nucleic acids, proteins and other analysts for diagnosis.

Abstract: The present invention disclosed the use of single nucleotide polymorphism (SNP) as the detection assay for human identification. Using the reversed dot-blot format and the flow through hybridization process, the process can be more efficient, less expensive and with similar or better power of exclusion in definitive identification. The present method can be applied to any other organisms.

Abstract: A method for making a secured personal identity card and procedures for validation and obtaining secure personal information includes the steps of (a) collecting a set of personal information from a user into an identity file wherein the identity file includes at least one section; (b) receiving an inputting personal identification number (“PIN”); and (c) comparing the inputting PIN with a master PIN preset in the identity file. Therefore, the user selectively and securely releases only specific information based upon the inputting PIN as compared to the biographical information guarded by the master PIN.

Abstract: The present invention disclosed the use of Allele-Specific-Oligonucleotide (ASO) as the detection assay for human HLA classification. Using the Reversed-Dot-Blotting format and the Flow Through Hybridization process, more efficient, fast and less expensive HLA classification can be achieved. The simple procedures for the process were described. This invention can also provides the method for genotyping as well as DNA analyses in general for different genes and different organisms.

Abstract: A method of embodying personal items with DNA fingerprints includes the steps of producing a DNA fingerprint from a raw biological sample provided by a consumer by a service producer, purchasing a personal item by a user, and embodying the DNA fingerprint with the personal item, so that the expensive treasured ornaments can be provided with an unmistakable signature, i.e. the DNA fingerprints, to mark these ornaments for security purpose.

Abstract: A method for making a secured personal identity card and procedures for validation and obtaining secure personal information includes the steps of (a) collecting a set of personal information from a user into an identity file wherein the identity file includes at least one section; (b) receiving an inputting personal identification number (“PIN”); and (c) comparing the inputting PIN with a master PIN preset in the identity file. Therefore, the user selectively and securely releases only specific information based upon the inputting PIN as compared to the biographical information guarded by the master PIN.

Abstract: This invention provides different methods for determining whether a target nucleic acid sequence is present in a sample and different methods for determining the amount of a target nucleic acid sequence present in a sample. This invention also provides various uses of these methods. Finally, this invention also provides devices where these methods are carried out.

Abstract: This invention provides methods for determining whether a target nucleic acid sequence is present in a sample and methods for determining the amount of a target nucleic acid sequence present in a sample using flow-through hybridisation technology. This invention also provides different embodiments of these methods. Finally, this invention also provides devices where these methods are carried out.