Abstract: The generation of a web site preview based on client presentation state of the client that will render the web site preview. Upon a service receiving a request to provide preview data for a web site preview corresponding to a web site identifier, the service determines client presentation state of the client(s) that is or are to render a web site preview using preview data that is to be provided in response to the request. The service selects a preview template at least in part based on the determined client presentation state. The service also populates the selected preview template with content from the web site to thereby generate preview data representing a preview of the web site identified by the web site identifier. The preview data is thus tailored to the presentation state of the client.

Abstract: A device may include a metal contact between a first isolation region and a second isolation region on a first surface of an epitaxial layer. The device may include a first sidewall and a second sidewall on a second surface of the epitaxial layer distal to the first isolation region and the second isolation region. The device may include a wavelength converting layer on the epitaxial layer between the first sidewall and the second sidewall.

Abstract: Disclosed herein are methods and systems for generating a merged dataset, comprising: accessing data comprising a core dataset and an additional dataset; identifying a plurality of common attributes between the core dataset and the additional dataset; determining a plurality of similarity scores between an inquiring entity in the core dataset and a plurality of candidate entities in the additional dataset, including, for each candidate entity of the plurality of candidate entities: calculating a similarity score for the candidate entity based at least in part on a distance-based score and a weight influence score; selecting one or more matches for the inquiring entity in the core dataset from the plurality of candidate entities in the additional dataset based at least in part on the plurality of similarity scores; and generating the merged dataset by adding the one or more selected matches for the inquiring entity to the core dataset.

Abstract: The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit Respiratory Syncytial Virus (RSV). The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from RSV infection. The invention also relates to methods of treating an RSV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.

Abstract: Provided are hybrid tRNA/pre-miRNA molecules, e.g., comprising a single tRNA and one, two or more pre-miRNA molecules, useful for the production and therapeutic delivery of an inserted RNA sequence, e.g., one or more miRNAs. Also provided are liposomes and nanoparticles that include the hybrid tRNA/pre-miRNA molecules. Methods of treating cancer by administration of the hybrid tRNA/pre-miRNA molecules are also provided.

Abstract: Disclosed herein is a head fixture for adhesively bonding a part of a golf club head to a body of the golf club head. The head fixture includes a bottom portion, including a body retainer, and a top portion, selectively attachable to the bottom portion and including pressure applicators spaced apart about the top portion. Each one of the pressure applicators comprises a ratcheting mechanism and a ribbed shaft engaged with the ratcheting mechanism such that, when the top portion is selectively attached to the bottom portion, the ribbed shaft is movable away from the body retainer into a position, associated with a pressure applied to the part of the golf club head by the ribbed shaft, and the ribbed shaft is non-movably fixable, relative to the body retainer, in the position.

Abstract: An instrument device manipulator (IDM) is attached to a surgical arm of a robotic system and comprises a surgical tool holder and an outer housing. The surgical tool holder includes an attachment interface that can secure a surgical tool in a front-mount configuration (where the attachment interface is on a face opposite of a proximal extension of the surgical tool) or a back-mount configuration (where the attachment interface is on the same face as the proximal extension of the surgical tool). The surgical tool holder may rotate continuously within the outer housing. In a back-mount configuration, the surgical tool holder may have a passage that receives the proximal extension of the tool and allows free rotation of the proximal extension about the rotational axis. A surgical drape separates the IDM and robotic arm from a tool, while allowing electrical and/or optical signals to pass therebetween.

Abstract: Systems, methods, and apparatus for using a multimodal response in the dynamic generation of client device output that is tailored to a current modality of a client device is disclosed herein. Multimodal client devices can engage in a variety of interactions across the multimodal spectrum including voice only interactions, voice forward interactions, multimodal interactions, visual forward interactions, visual only interactions etc. A multimodal response can include a core message to be rendered for all interaction types as well as one or more modality dependent components to provide a user with additional information.

Abstract: The present invention provides compounds of the structural Formula (I), and pharmaceutically acceptable salts thereof, wherein, are as defined herein, pharmaceutical compositions comprising one or more such compounds (alone and in combination with one or more other therapeutically active agents), and methods for their preparation and use, alone and in combination with other therapeutic agents, as antagonists of A2a and/or A2b receptors, and in the treatment of a variety of diseases, conditions, or disorders that are mediated, at least in part, by the adenosine A2a receptor and/or the adenosine A2b receptor.

Abstract: Systems and methods for simulating subterranean regions having multi-scale, complex fracture geometries in a realistic simulation environment, which includes in the modeling process three-dimensional multi-scale rock discontinuities, hydraulic fractures, and heterogenous reservoir properties. Non-intrusive embedded discrete fracture modeling formulations are applied in conjunction with commercial or in-house simulators to efficiently and accurately model subsurface characteristics including three-dimensional geometries having combinations of complex hydraulic fractures and multi-scale rock discontinuities.

Abstract: Multi-mode personal transportation and delivery devices and methods of use are disclosed herein. A device can include a communications interface, the communications interface configured to provide vehicle-to-everything communications, a device controller comprising: a processor; and a memory for storing instructions, the processor executing the instructions to: receive a first message from a service provider that the transportation device is to relocate to a location based on user demand; and activate a redistribution mode to cause the transportation device to autonomously navigate to the location.

Abstract: Disclosed herein is a casting cluster for casting a body of a golf club head made of titanium or a titanium alloy. The casting cluster comprises a receptor and a plurality of runners coupled to the receptor and configured to receive molten metal from the receptor. The casting cluster also includes at least twenty-eight main gates. At least two of the main gates are coupled to each of the runners and each main gate is configured to receive molten metal from a corresponding one of the plurality of runners. The casting cluster further comprises at least twenty-eight molds. Each mold of the at least twenty-eight molds is configured to receive molten metal from a corresponding one of the main gates and to cast a body of a golf club head that has a volume of at least 100 cm3.

Abstract: Disclosed herein is a casting cluster for casting a body of a golf club head made of titanium or a titanium alloy. The casting cluster comprises a receptor and a plurality of runners coupled to the receptor and configured to receive molten metal from the receptor. The casting cluster also includes at least forty main gates. At least two of the main gates are coupled to each of the runners and each main gate is configured to receive molten metal from a corresponding one of the plurality of runners. The casting cluster further comprises at least forty molds. Each mold of the at least forty molds is configured to receive molten metal from a corresponding one of the main gates and to cast a body of an iron-type golf club head.

Abstract: Golf club heads are described having a club head portion, a shaft portion connected to the club head portion, and a grip portion connected to the shaft portion. The club head portion has a heel portion, a sole portion, a toe portion, a crown portion, a hosel portion, and a striking face. The striking face can have a center face roll contour, a toe side roll contour, a heel side roll contour, a center face bulge contour, a crown side bulge contour, and a sole side bulge contour. The toe side roll contour can be more lofted than the center face roll contour. The heel side roll contour can be less lofted than the center face roll contour. The crown side bulge contour can be more open than the center face bulge contour, and the sole side bulge contour can be more closed than the center face bulge contour.

Abstract: Disclosed herein is a casting cluster for casting a body of a golf club head made of titanium or a titanium alloy. The casting cluster comprises a receptor and a plurality of runners coupled to the receptor and configured to receive molten metal from the receptor. The casting cluster also includes at least twenty-eight main gates. At least two of the main gates are coupled to each of the runners and each main gate is configured to receive molten metal from a corresponding one of the plurality of runners. The casting cluster further comprises at least twenty-eight molds. Each mold of the at least twenty-eight molds is configured to receive molten metal from a corresponding one of the main gates and to cast a body of a golf club head that has a volume of at least 100 cm3.

Abstract: Disclosed herein is a casting cluster for casting a body of a golf club head made of titanium or a titanium alloy. The casting cluster comprises a receptor and a plurality of runners coupled to the receptor and configured to receive molten metal from the receptor. The casting cluster also includes at least forty main gates. At least two of the main gates are coupled to each of the runners and each main gate is configured to receive molten metal from a corresponding one of the plurality of runners. The casting cluster further comprises at least forty molds. Each mold of the at least forty molds is configured to receive molten metal from a corresponding one of the main gates and to cast a body of an iron-type golf club head.

Abstract: Golf club heads are described having a club head portion, a shaft portion connected to the club head portion, and a grip portion connected to the shaft portion. The club head portion has a heel portion, a sole portion, a toe portion, a crown portion, a hosel portion, and a striking face. The striking face can have a center face roll contour, a toe side roll contour, a heel side roll contour, a center face bulge contour, a crown side bulge contour, and a sole side bulge contour. The toe side roll contour can be more lofted than the center face roll contour. The heel side roll contour can be less lofted than the center face roll contour. The crown side bulge contour can be more open than the center face bulge contour, and the sole side bulge contour can be more closed than the center face bulge contour.

Abstract: Disclosed herein is a casting cluster for casting a body of a golf club head made of titanium or a titanium alloy. The casting cluster comprises a receptor and a plurality of runners coupled to the receptor and configured to receive molten metal from the receptor. The casting cluster also includes at least forty main gates. At least two of the main gates are coupled to each of the runners and each main gate is configured to receive molten metal from a corresponding one of the plurality of runners. The casting cluster further comprises at least forty molds. Each mold of the at least forty molds is configured to receive molten metal from a corresponding one of the main gates and to cast a body of an iron-type golf club head.

Abstract: Disclosed herein is a casting cluster for casting a body of a golf club head made of titanium or a titanium alloy. The casting cluster comprises a receptor and a plurality of runners coupled to the receptor and configured to receive molten metal from the receptor. The casting cluster also includes at least twenty-eight main gates. At least two of the main gates are coupled to each of the runners and each main gate is configured to receive molten metal from a corresponding one of the plurality of runners. The casting cluster further comprises at least twenty-eight molds. Each mold of the at least twenty-eight molds is configured to receive molten metal from a corresponding one of the main gates and to cast a body of a golf club head that has a volume of at least 100 cm3.

Abstract: Disclosed herein is a casting cluster for casting a body of a golf club head made of titanium or a titanium alloy. The casting cluster comprises a receptor and a plurality of runners coupled to the receptor and configured to receive molten metal from the receptor. The casting cluster also includes at least twenty-eight main gates. At least two of the main gates are coupled to each of the runners and each main gate is configured to receive molten metal from a corresponding one of the plurality of runners. The casting cluster further comprises at least twenty-eight molds. Each mold of the at least twenty-eight molds is configured to receive molten metal from a corresponding one of the main gates and to cast a body of a golf club head that has a volume of at least 100 cm3.