Abstract: The invention relates to biocompatible polymer gel compositions useful in facilitating and maintaining hemostasis. The biocompatible polymeric gel composition is comprised of (a) one or more than one polyanionic polymer, (b) one or more than one polycationic polymer, and (c) a solvent. A preferred composition includes sodium alginate, chitosan, and water to produce an adhesive hemostatic device that is useful in facilitating and maintaining rapid hemostasis.

Abstract: A specimen holder includes a body, a sleeve, and a wireless transponder. The body has distal and proximal portions, the distal portion including a surface that carries a specimen upon engagement of the body with the specimen, and the proximal portion including a first pair of parallel surfaces. The sleeve has distal and proximal portions, a side wall, and an internal cavity at least partially enclosed by the side wall. The distal portion of the sleeve includes a second pair of parallel surfaces. The wireless transponder is sized to be positioned within the internal cavity of the sleeve. The sleeve is attachable to the body by capturing one of the first and second pairs of parallel surfaces between the other of the first and second pairs of parallel surfaces.

Abstract: A mechanical design for a braking system of a delivery device is described. The braking system includes one or more brake modules. Each brake module is configured to engage a different wheel of the delivery device to stop movement of the wheel when power to the brake module is less than a threshold. Each brake module includes: an electromagnet; a magnetic plate; a pawl configured to engage a wheel to stop movement of the wheel; a solenoid comprising a solenoid pin, the solenoid pin having a first end coupled to the magnetic plate and having a second end coupled to the pawl, and a manual override mechanism that is configured to allow movement of the wheel when the power to the brake module is less than the threshold. The brake module is configured to disable the manual override mechanism when the power to the brake module is greater than or equal to a threshold.

Abstract: Container system and method for freezing (and subsequently thawing) a liquid such as a drug substance, such that all containers in a set have a uniform width, hence uniform freeze-path length, in the widthwise direction and perpendicular to major walls of the containers, irrespective of the particular length, height, and volumetric capacity of the various containers in the set. This leads to uniform freezing performance and thereby reduces cryoconcentration. The system also eliminates or reduces ice-bridging, and the potential for containers rupturing during freezing and thawing operations.

Abstract: A vehicle for an infant having a vehicle body (10) having a front end (11) and a rear end (12), a front steering unit (20) mounted on the front end (11) and including a steering column (21) on which a front wheel (31) and a handlebar (22) are mounted, a seat (41) mounted between the front end (11) and the rear end (12), a first rear wheel (321) connected to the vehicle (10) body via a first wheel carrier (171) and a second rear wheel (322) connected to the vehicle body (10) via a second wheel carrier (172), the first and the second wheel carriers (171, 172) being rotatably mounted on the rear end (12) between a compact configuration and a deployed configuration, the first and the second wheel carriers (171, 172) being movable between the two configurations independently of each other.

Abstract: An irradiation device for additively manufacturing three-dimensional objects may include a beam generation device configured to generate an energy beam, an optical modulator including a micromirror array disposed downstream from the beam generation device, and a focusing lens assembly disposed downstream from the optical modulator. The micromirror array may include a plurality of micromirror elements configured to reflect a corresponding plurality of beam segment of the energy beam along a beam path incident upon the focusing lens assembly. The focusing lens assembly may include one or more lenses configured to focus the plurality of beam segments such that for respective ones of a plurality of modulation groups including a subset of micromirror elements, a corresponding subset of beam segments are focused to at least partially overlap with one another at a combination zone corresponding to the respective modulation group.

Abstract: An exercise machine includes a shaft configured to rotate about an axis; a spool configured to receive a strap and drive rotation of the shaft about the axis in response to movement of the strap; a flywheel configured to rotate about the axis; one or more conductive coils arranged to generate magnetic fields that induce eddy currents in the flywheel; a clutch configured to engage and disengage transmission of torque between the spool and the flywheel; and a spring arranged around the axis, the spring configured to exert a return torque on the spool about the axis in response to rotation of the shaft.

Abstract: The present disclosure provides systems, devices, and methods for abrasive articles and manufacturing the same.

Abstract: Belt-fed tube cleaning systems and methods may include a tube cleaning projectile belt loaded into a pneumatic firing apparatus employing a cam-activated indexing element and projectile belt separation objects that permit or cause removal of individual tube cleaning projectiles from the tube cleaning projectile belt for semi-automatic tube cleaning operation thereof.

Abstract: A vent system for use during respiratory therapy with a flow of pressurized gas may provide a continuous vent flow of gas. The vent system may include a vent housing having an outer wall; an inner wall, the inner wall defining an inlet for the flow of gas; and a base positioned between the outer wall and the inner wall, the base having at least one first orifice and at least one second orifice. The vent system may include a membrane, the membrane being shaped and dimensioned such that the membrane does not cover the at least one first orifice to allow the vent flow through the at least one first orifice, and the membrane being shaped and dimensioned such that in a first position the membrane is positioned over the at least one second orifice to allow the vent flow through the at least one second orifice.

Abstract: A flat catamaran watercraft construction is provided having a bow that defines a “split V” configuration in which the bottom surface of each of the two asymmetrical catamaran hull portions at the forward section of each hull portion slope upward from the inboard side of the hull portion to the outboard side of the hull portion. Such upward slope of the bottom of each hull portion sheds water and waves to the outboard sides of the vessel as it travels through the water in order to minimize the amount of water and spray that is directed upward between the individual hull portions towards the passengers. The rear portions of each such hull portion define an angled slope along both inboard and outboard sides, which angled slopes allow the rear portion of the watercraft to slide and drift sideways along the surface of the water as the watercraft turns. The flat catamaran hull portions and deck of the watercraft are preferably of unibody construction, such that they are formed (e.g.

Abstract: A non-shortening catheter balloon having a longitudinal axis and an inflatable balloon able to be affixed to a catheter shaft is provided. The balloon has an uninflated length which remains relatively unchanged upon inflation and is formed of least two helically oriented wrapped passes of balloon materials at a balanced force angle. Methods of making this balloon are also provided.

Abstract: An assembly is provided for a structure. This assembly includes a composite skin and a thermal anti-icing system. The composite skin extends between an exterior surface and an interior surface. The thermal anti-icing system includes a susceptor and a waveguide. The susceptor and the waveguide are integrated into the composite skin between the exterior surface and the interior surface. The waveguide is configured to direct microwaves to the susceptor for melting and/or preventing ice accumulation on the exterior surface.

Abstract: This disclosure relates to blood flow reversal valves and related systems and methods. In certain aspects of the invention, a blood flow reversal valve includes a first member having a first passage and a second passage, and a second member having a first passage and a second passage. The first and second members are rotatably fixed relative to one another such that the first passage of the first member is aligned with the first passage of the second member and the second passage of the first member is aligned with the second passage of the second member. A flow directing element is disposed in the cavity and is moveable relative to the first and second members between a first position in which the first passage of the first member and the first passage of the second member are fluidly connected and a second position in which the first passage of the first member and the second passage of the second member are fluidly connected.

Abstract: The invention relates to compounds of Formula I: or a pharmaceutically acceptable salt, tautomer, or stereoisomer, thereof, wherein the variables are as defined herein. The present invention further provides pharmaceutical compositions comprising such compounds and methods of using such compounds for method for treating, preventing, inhibiting, ameliorating, or eradicating the pathology and/or symptomology of cryptosporidiosis by administering such a compound.

Abstract: Disclosed are nano/micromotor devices, systems, and methods for providing payloads in the gastrointestinal system. In one aspect, a micromotor for a gastrointestinal tract includes a micromotor body including a one or more material layers to provide a structure that surrounds a hollow interior region and has an opening to an exterior of the micromotor body; one or more particles including a biocompatible metal element, the one or more particles contained in the interior region of the micromotor body; a coating coupled to the structure of the micromotor body; and a payload material, in which the micromotor is structured to move in a fluid of a gastrointestinal system based on a reaction between the one or more particles and a constituent or a condition of the fluid, such that the reaction generates bubbles that accelerate out of the opening of the micromotor body to propel the micromotor in the fluid.

Abstract: A mounting apparatus for exercise equipment includes a first elongate support member having a first end, a second end, and a connector positioned along a first portion of the first elongate support member and arranged to detachably connect to a portion of the exercise equipment. The mounting apparatus further includes a second elongate support member having a first end and a second end meeting the first end of the first elongate support member at a first vertex. The mounting apparatus further includes a third elongate support member having a first end and a second end meeting the first end of the first elongate support member at a second vertex.