Patents by Inventor Josh Friedman

Josh Friedman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Magnetic resonance imaging and spectroscopy of low concentration solutes with exchangeable protons using label transfer modules: frequency transfer, inversion transfer, and dephasing transfer
    Patent number: 9140769
    Abstract: An embodiment of the current invention provides a method for magnetic resonance (MR) imaging or spectroscopy, comprising: (a) selectively exciting exchangeable solute protons or protons of exchangeable solute-based water molecules within a frequency range in a subject using at least one frequency-selective radio frequency (RF) pulse, wherein the frequency range encompasses characteristic resonance frequencies of the exchangeable solute protons or protons of exchangeable solute-based water molecules, wherein the frequency range is substantially non-overlapping with a characteristic resonance frequency of bulk water protons in the subject, wherein the at least one frequency selective RF pulse performs a substantially minimal excitation on the bulk water protons, and wherein the at least one frequency-selective RF pulse, sometimes in combination with a time period that separates the at least one frequency-selective RF pulse, magnetically labels the exchangeable solute protons or the exchangeable solute-based wat
    Type: Grant
    Filed: August 10, 2010
    Date of Patent: September 22, 2015
    Assignee: The Johns Hopkins University
    Inventors: Peter van Zijl, Josh Friedman
  • MAGNETIC RESONANCE IMAGING AND SPECTROSCOPY OF LOW CONCENTRATION SOLUTES WITH EXCHANGEABLE PROTONS USING LABEL TRANSFER MODULES: FREQUENCY TRANSFER, INVERSION TRANSFER, AND DEPHASING TRANSFER
    Publication number: 20120289818
    Abstract: An embodiment of the current invention provides a method for magnetic resonance (MR) imaging or spectroscopy, comprising: (a) selectively exciting exchangeable solute protons or protons of exchangeable solute-based water molecules within a frequency range in a subject using at least one frequency-selective radio frequency (RF) pulse, wherein the frequency range encompasses characteristic resonance frequencies of the exchangeable solute protons or protons of exchangeable solute-based water molecules, wherein the frequency range is substantially non-overlapping with a characteristic resonance frequency of bulk water protons in the subject, wherein the at least one frequency selective RF pulse performs a substantially minimal excitation on the bulk water protons, and wherein the at least one frequency-selective RF pulse, sometimes in combination with a time period that separates the at least one frequency-selective RF pulse, magnetically labels the exchangeable solute protons or the exchangeable solute-based wat
    Type: Application
    Filed: August 10, 2010
    Publication date: November 15, 2012
    Applicant: THE JOHNS HOPKINS UNIVERSITY
    Inventors: Peter van Zijl, Josh Friedman