Patents by Inventor Joshua Adam LERMAN

Joshua Adam LERMAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12098407
    Abstract: Provided herein are compositions and methods for uncoupling the yield and productivity of an isoprenoid compound produced in a host cell. In some embodiments, the yield and productivity are uncoupled by genetically modifying the host cell to reduce flux through the citric acid cycle (TCA). In other embodiments, the yield and productivity are uncoupled by reducing the levels of ATP in the host cell.
    Type: Grant
    Filed: June 5, 2020
    Date of Patent: September 24, 2024
    Assignee: Amyris Inc.
    Inventors: Penelope R. Chua, Joshua Adam Lerman, Thomas Jon Scherbart, Chandresh Thakker, Annie Ening Tsong, Hanxiao Jiang
  • Publication number: 20220307059
    Abstract: Provided herein are compositions and methods for uncoupling the yield and productivity of an isoprenoid compound produced in a host cell. In some embodiments, the yield and productivity are uncoupled by genetically modifying the host cell to reduce flux through the citric acid cycle (TCA). In other embodiments, the yield and productivity are uncoupled by reducing the levels of ATP in the host cell.
    Type: Application
    Filed: June 5, 2020
    Publication date: September 29, 2022
    Inventors: Penelope R. CHUA, Joshua Adam LERMAN, Thomas Jon SCHERBART, Chandresh THAKKER, Annie Ening TSONG, Hanxiao JIANG